The collection of genes that influence alcohol-related behavior in flies and worms (Tables 1 and 2) correspond to 293 unique orthologous genes in humans (hereafter iMO–human genes or orthologs; Table 3). Twenty-two of the iMO–human genes are derived from studies in both flies and worms, while 182 and 89 of the iMO–human genes are exclusively from studies in flies and worms, respectively. The identification of orthologs in some cases can be somewhat challenging (cf. Hu et al., 2011), and therefore, the list of genes in Table 3 should be viewed as highly representative of the current sum of iMO–human orthologs as opposed to being definitive for the inclusion or exclusion of any single potential iMO–human gene.
