In summary, here we have briefly reviewed the growing, but still relatively small, literature on transcriptomics with regard to pertinent issue of life-span development in general and child development in particular. The ever-changing technology has made studies of transcriptomes affordable to a large community of scientists; the existing public and private databases have provided/will provide wonderful sources of reference to the typical development of the brain during different stages of human life. The accumulation of data on the spatial and temporal structures of the transcriptome in the brain tissue—notably the data obtained using methods of transcriptome profiling with high-resolution RNA-Seq—and the organization of the data into the resources described above, provide a needed spring board for the development of new types of studies of the transcriptome—studies that correlate its structure and dynamics with behavioral development across different stages of human life, in its variable environments, and in its typical and atypical manifestations.
