Array heritability estimates derived from genotyped SNPs based on PC-Relate kinship estimates29, to account for population stratification in the kinship estimate, using GEAR30 in the non-Hispanic whites was 15.5% (95% CI=13.9%-17.1%) for SBP, 15.1% (95% CI=13.5%-16.7%) for DBP, and 14.5% (95% CI=12.7%-16.2%) for PP, increasing only modestly when adding imputed SNPs to 16.1% (95% CI=14.5-17.7%) for SBP, 17.0% (95% CI=15.6%-18.4%) for DBP, and 15.6% (95%CI=14.0%-17.2%) for PP. These estimates were similar to estimates not accounting for population stratification in the kinship estimates but adjusting for it in the phenotype model instead using GCTA31 (SBP h2=16.8%, 95% CI=15.1%-18.6%); this may be because the ancestry effect in non-Hispanic whites is modest. Sample sizes were too small to evaluate other GERA groups.
