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Chunk #17 — Results — Differences in SBP, DBP, and PP effects

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Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
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We tested whether the normalized effect size of each SNP was greater in SBP or DBP (Online Methods, Supplementary Table 9); 26.2% of the SNPs had significantly different normalized effect sizes for between SBP and DBP (P<0.00013, Bonferroni correction for 386 SNPs); of these, for 57.4% the normalized effect was greater for SBP than DBP.