While ADH1B*3 is thought to result in faster metabolism of alcohol and higher levels of acetaldehyde, participants in the present study with ADH1B*3 alleles did not differ in BrAC from those with ADH1B*1. This is consistent with prior studies using oral alcohol administration (Taylor et al., 2008). Studies using intravenous alcohol administration and a BrAC clamping method are better able to detect differences in alcohol elimination rate as a function of ADH polymorphisms (Neumark et al., 2004). In addition, more research is needed to determine if ADH1B*3 results in faster production of acetaldehyde.
