We constructed PRSs for 3,642 Hispanic/Latina women from the WHI based on combinations of results from EA and HCHS/SOL GWASs. Figure 3 demonstrates the highest variance explained obtained by the highest performing EA-based PRS (SNP selection and weight estimation by EA GWAS), and the highest variance explained by any of the approaches. Table 3 provides information about the best performing EA-based PRS, and the overall best performing PRS.
