Heritability of each trait in UKBB, BBJ and PAGE was estimated using LD score regression49 with ancestry-matched LD reference panels. We calculated the cross-population genetic correlation between UKBB, BBJ and PAGE using POPCORN16 with default parameters. POPCORN requires the LD score49 and cross-covariance score as the input. We used the pre-computed EUR-EAS scores (available from the POPCORN website), and computed EUR-AFR and EAS-AFR scores on 1KG Phase 3 samples using the ‘compute’ function provided by POPOCORN.
