prospective cohort study of the Taiwanese population. Participants were 30 to 70 years old at recruitment. Among the 33 quantitative traits examined in UKBB, we identified 21 traits that were also available in TWB. We used 14,232 samples genotyped on the TWBv2 custom array and imputed against the 1KG samples, the same dataset used in the PRS analysis of our recent TWB quantitative trait GWAS study32, to evaluate the predictive performance of different polygenic prediction methods. Following the same sample-level and variant-level QC procedures used in the UKBB analysis, the final analytic sample included 10,149 unrelated individuals of EAS ancestry that had complete data across the 21 traits. Detailed information on the sample characteristics and collection of phenotypes can be found in Chen et al.32,33
