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Chunk #26 — 2. Inhibitory Response Control — 2.3. Relationship to Substance Use Disorders — 2.3.2. Tests of Waiting

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Dissecting impulsivity and its relationships to drug addictions.
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Though 5CSRTT and DRL are viewed from the perspective that they both measure waiting, it is clear that their individual relationships to addiction-like behaviors are different. Waiting in the 5CSRTT predicts self-administration behaviors (much like tests of action inhibition do), but drug experience does not impair waiting in this task at the group level (and, indeed, reduces it in rats with baseline high impulsivity). Waiting in the DRL, on the other hand, is highly sensitive to drug experience. This suggests that, even within one domain of inhibitory response control, different tests exhibit unique relationships to addiction.