been reproducibly associated with both alcoholism (Agrawal et al., 2006, Bauer et al., 2007, Covault et al., 2004, Edenberg et al., 2004, Enoch et al., 2006, Fehr et al., 2006, Lappalainen et al., 2005, Lind et al., 2008a, Lind et al., 2008b, Pierucci-Lagha et al., 2005, Soyka et al., 2008) and an electroencephalography (EEG) measure, the β frequency band (Edenberg et al., 2004). Alcoholics (Rangaswamy et al., 2002) and their at-risk offspring (Rangaswamy et al., 2004) have increased power in the β frequency band (13–28 Hz). Furthermore, GABRA2 has been associated with childhood conduct disorder symptoms (Dick et al., 2006) and trajectories of externalizing behavior (Dick et al., 2009). The SNPs reported in these studies expand a region with two haplotype blocks in high linkage disequilibrium (LD) facilitating allele comparison across studies. The majority of studies on alcohol dependence or abuse (Agrawal et al., 2006, Bauer et al., 2007, Covault et al., 2004, Edenberg et al., 2004, Enoch et al., 2006, Fehr et al., 2006, Lappalainen et al., 2005, Lind et al., 2008a, Lind et al., 2008b, Pierucci-Lagha et al., 2005, Soyka et al., 2008) reported the minor allele associated with the disorder.
