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Chunk #2 — 2. Neurodevelopmental disorders — the potential of hiPSCs

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Human induced pluripotent stem cells for modelling neurodevelopmental disorders.
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Neurodevelopmental disorders are a broad group of disorders in which development of the CNS is altered so that the way sensory, motor and cognitive information is acquired and processed in postnatal development is disturbed. In turn, these disturbances affect how neural networks are modified by ongoing neuronal activity, resulting in a wide spectrum of emotional, cognitive, and motor deficits – including, for example, impaired language and/or non-verbal communication, impaired memory and learning, and motor dysfunction.