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Chunk #1 — RESULTS — GWAS of algorithmically defined case-control PTSD.

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Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program.
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was performed using METAL25. Combat exposure information was available for only a subset (51.2%) of the sample (Supplementary Table 1), and GWAS of that subset yielded no genome-wide significant (GWS) findings (Supplementary Table 2 shows findings at P < 10−6). However, genetic correlation (rg) between the categorical trait (i.e., diagnosis of) PTSD in those combat-exposed and in all subjects irrespective of combat exposure status was 0.969 (s.e. 0.049, P = 7.64 × 10−89), and therefore results for the latter larger, more informative, sample are presented here.