(d) We compared the GWAS association results to a meta-analysis of gene expression data from 12 studies of post-mortem brain tissue in MDD cases compared with controls (10 frontal cortex and 2 cerebellum studies). These data are available via the Stanley Foundation (http://www.stanleygenomic.org). There were five genes with GWAS p<0.05 (all had gene expression changes significant at p 0.0004 – 0.007). The genes were: SGCG (sarcoglycan), CALD1 (caldesmon 1), EEF1A1 (eukaryotic translation elongation factor 1 alpha 1), CFLAR (CASP8 and FADD-like apoptosis regulator), and TP73L (tumor protein p73-like). There is no overlap of this list with the PCLO interactors or MDD candidate genes from the literature.
