All individuals participated in the following assessments: 1) psychiatric diagnoses and symptom counts were gathered using the c-DIS (Robins, Cottler et al. 1998), 2) participants were interviewed on their lifetime drug and alcohol use using the timeline follow-back methodology (Skinner and Allen 1982; Skinner and Sheu 1982; Sobell, Sobell et al. 1988; Sobell and Sobell 1990), 3) medical histories were reviewed in an interview by a trained research associate, and 4) blood was drawn to test liver functions. Approval for the study was obtained from a free-standing independent human subjects research review committee [Independent Review Consulting, Corte Madera, CA], and written informed consent was obtained from all research participants.