Although the addition of large volumes of interaction data for drugs, both with food and other drugs (see section and Table 1), is highly beneficial, the average user may find these large datasets difficult to navigate. The most common reason for accessing DrugBank's drug interaction data is to cross-reference foods/drugs that are known to interact with a given drug. It is with this use case in mind that we developed and implemented a web-based interaction checker. While there was a drug interaction checker available in DrugBank 5.0, this has been greatly enhanced in both form and functionality for DrugBank 6.0. This tool can be accessed under ‘Interaction Checker’ or by navigating to the URL (https://go.drugbank.com/drug-interaction-checker).