paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #17 — Results

Source
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
Embedded
yes

Text

Table 3 summarises results of the eQTL enrichment analysis for SNPs selected at varying p-value cutoffs from the primary cross-disorder meta-analysis. We noted a significantly greater proportion of brain eQTL markers in cross-disorder-selected SNPs than expected in view of their distribution of frequencies for minor alleles. We consistently noted this enrichment for two of the three studies of post-mortem brain eQTL for various p-value cutoffs (table 3) and when analyses included all SNPs or were restricted to retain only one SNP tagging (r2>0·8) an associated region. No consistent enrichment was noted in the three non-brain-tissue datasets (table 3).