Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

paper Cited Public

Authors: Cross-Disorder Group of the Psychiatric Genomics Consortium
Year: 2013
Journal: Lancet (London, England)
PMID: 23453885
DOI: 10.1016/S0140-6736(12)62129-1
PMCID: PMC3714010

BACKGROUND: Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying genetic effects shared between the five disorders in the Psychiatric Genomics Consortium: autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia. METHODS: We analysed genome-wide single-nucleotide polymorphism (SNP) data for the five disorders in 33,332 cases and 27,888 controls of European ancestory. To characterise allelic effects on each disorder, we applied a multinomial logistic regression procedure with model selection to identify the best-fitting model of relations between genotype and phenotype. We examined cross-disorder effects of genome-wide significant loci previously identified for bipolar disorder and schizophrenia, and used polygenic risk-score analysis to examine such effects from a broader set of common variants. We undertook pathway analyses to establish the biological associations underlying genetic overlap for the five disorders. We used enrichment analysis of expression quantitative trait loci (eQTL) data to assess whether SNPs with cross-disorder association were enriched for regulatory SNPs in post-mortem brain-tissue samples. FINDINGS: SNPs at four loci surpassed the cutoff for genome-wide significance (p<5×10(-8)) in the primary analysis: regions on chromosomes 3p21 and 10q24, and SNPs within two L-type voltage-gated calcium channel subunits, CACNA1C and CACNB2. Model selection analysis supported effects of these loci for several disorders. Loci previously associated with bipolar disorder or schizophrenia had variable diagnostic specificity. Polygenic risk scores showed cross-disorder associations, notably between adult-onset disorders. Pathway analysis supported a role for calcium channel signalling genes for all five disorders. Finally, SNPs with evidence of cross-disorder association were enriched for brain eQTL markers. INTERPRETATION: Our findings show that specific SNPs are associated with a range of psychiatric disorders of childhood onset or adult onset. In particular, variation in calcium-channel activity genes seems to have pleiotropic effects on psychopathology. These results provide evidence relevant to the goal of moving beyond descriptive syndromes in psychiatry, and towards a nosology informed by disease cause. FUNDING: National Institute of Mental Health.

Figure 1

Manhattan plot of primary fixed-effects meta-analysisHorizontal line shows threshold for genome-wide significance (p<5×10−8).

LLM interpretation

This is a Manhattan plot showing the results of a primary fixed-effects meta-analysis across 22 chromosomes. The y-axis represents the $-\log_{10}(p\text{-value})$, with a red horizontal line indicating the genome-wide significance threshold of $p < 5 \times 10^{-8}$. Several genomic loci, including *ITIH3*, *MHC*, and *CACNB2*, are labeled as they exceed or approach this significance threshold.

Figure 2

Association results and forest plots showing effect size for genome-wide significant loci by disorderData in parentheses are numbers of cases or controls. Het_p=p value for the heterogeneity test. Het_I=heterogeneity test statistic. IQS=imputation quality score (INFO). ln(OR)=log of the odds ratio (OR). F=frequency. SE=standard error of the log OR. ADHD=attention deficit-hyperactivity disorder. ASD=autism spectrum disorders. BPD=bipolar disorder. MDD=major depressive disorder. *Number of studies in which the variant was directly genotyped.

LLM interpretation

This figure consists of four forest plots (labeled A-D) showing the association of specific genetic variants (rs2535629, rs1191454, rs1024582, and rs2799573) with five psychiatric disorders (ADHD, ASD, BPD, MDD, and Schizophrenia). Each panel displays a table of statistics—including p-values, case/control frequencies, and log odds ratios (ln(OR))—alongside a plot of effect sizes and 95% confidence intervals. The "All" row at the bottom of each panel provides a pooled effect size represented by a diamond, indicating the overall association across the studied groups.

Figure 3

Pair-wise cross-disorder polygene analysisWe derived polygene risk scores for each disorder (discovery sets) and applied them sequentially to the remaining disorders (target sets). Results are grouped by each discovery set. Each pair is shown on the x-axis and the proportion of variance explained for the target disorder (estimated via Nagelkerke’s pseudo R2) on the y-axis. For purposes of illustration, three pT cutoffs are shown, but appendix p 62 shows the proportion of variance results for a broader range of cutoffs. pT=training-set p value (used to select training set SNPs). Significance of results: a=p<0·05; b=p<10−4; c=p<10−8; d=p<1012; e=p<10−16; f=p<10−50. ADHD=attention deficit-hyperactivity disorder. ASD=autism spectrum disorders. BPD=bipolar disorder. MDD=major depressive disorder.

LLM interpretation

This grouped bar chart shows the proportion of variance explained ($R^2$) for target psychiatric disorders using polygene risk scores derived from different discovery sets. The x-axis lists pairs of disorders grouped by discovery set (ADHD, ASD, BPD, MDD, and Schizophrenia), while the y-axis measures $R^2$. The highest variance is explained when Schizophrenia is the discovery set for BPD and when BPD is the discovery set for Schizophrenia, with significance markers (a-f) indicating varying p-value thresholds.

#	Section	Preview
0	Introduction	Psychiatric nosology arose in central Europe towards the end of the 19th century, in particular with…
1	Introduction	The pathogenic mechanisms of psychiatric disorders are largely unknown, so diagnostic boundaries are…
2	Introduction	We formed the Psychiatric Genomics Consortium (PGC) in 2007, to undertake meta-analyses of…
3	Introduction	In this first report from the PGC Cross-Disorder Group, we analyse data on genome-wide…
4	Methods — Samples and genotypes	The sample for these analyses consisted of cases, controls, and family-based samples assembled for…
5	Methods — Samples and genotypes	To ensure comparability between samples, raw genotype and phenotype data for each study were…
6	Methods — Statistical analysis	In the primary analysis, we combined effects of each disease analysis by a meta-analytic approach…
7	Methods — Statistical analysis	To characterise the specificity of the allelic effects for our main findings, we examined the…
8	Methods — Statistical analysis	To examine shared polygenic risk at an aggregate level between pairs of diagnoses, we used…
9	Methods — Statistical analysis	biologically related genes (appendix pp 14–16). We did eQTL enrichment analysis20 to assess…
10	Methods — Role of the funding source	The sponsor of the study had no role in study design, data collection, data analysis, data…
11	Results	The final dataset consisted of 33 332 cases and 27 888 controls (including pseudocontrols formed…
12	Results	Figure 1 shows the Manhattan plot of the primary results. Four independent regions contained SNPs…
13	Results	1·5 Mb of the peak SNP with association p values less than 10−4 and r2 less than 0·2 with the…
14	Results	Forest plots for genome-wide significant SNPs showed the same direction of effect for most or all of…
15	Results	Figure 3 shows the proportion of variance explained in target sets (Nagelkerke’s pseudo R2 from…
16	Results	After correction for multiple testing (appendix pp 14–16), we noted significant enrichment for a…
17	Results	Table 3 summarises results of the eQTL enrichment analysis for SNPs selected at varying p-value…
18	Discussion	This study is the largest genome-wide analysis of psychiatric illness so far and the first to…
19	Discussion	In view of extensive linkage disequilibrium in the 3p21.1 region, encompassing more than 30 genes,…

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Paternal valproate use and impact of shared genetic susceptibility on child neurodevelopment.	Olstad EW et al.	—	2025	→
Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children.	Joo YY et al.	—	2025	→
Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety.	Bäckman J et al.	—	2025	→
Polymorphisms in <i>CACNA1A</i>, <i>CACNA1C</i>, and <i>CACNA1H</i> Genes in Korean Pediatric Patients with Developmental Delay and Intellectual Disability: A Focus on Epilepsy Comorbidity.	Han JY	—	2025	→
Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course.	Noble AJ et al.	—	2025	→
Prevalence, Socio-Demographic Characteristics, and Co-Morbidities of Autism Spectrum Disorder in US Children: Insights from the 2020-2021 National Survey of Children's Health.	Salehi M et al.	—	2025	→
Psychiatric disorders: teasing apart genetic similarities and differences.	Xu J et al.	—	2025	→
Sociodemographic Characteristics, Dementia, and Familial Risk in Patients With Paraphrenia: A Danish Register-Based Cohort Study.	Wium-Andersen IK et al.	—	2025	→
Structure of a polymorphic repeat at the <i>CACNA1C</i> schizophrenia locus.	Moya R et al.	—	2025	→
Synapse-to-Nucleus ERK→CREB Transcriptional Signaling Requires Dendrite-to-Soma Ca<sup>2+</sup> Propagation Mediated by L-Type Voltage-Gated Ca<sup>2+</sup> Channels.	Zent KH et al.	—	2025	→
Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases.	Ma Y et al.	—	2025	→
The effect of fampridine on working memory: a randomized controlled trial based on a genome-guided repurposing approach.	Papassotiropoulos A et al.	—	2025	→
The trait-specific timing of accelerated genomic change in the human lineage.	Kun E et al.	—	2025	→
Translating Molecular Psychiatry: From Biomarkers to Personalized Therapies-A Narrative Review.	Capatina TF et al.	—	2025	→
Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records.	Þorsteinsson H et al.	—	2025	→
A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings.	Del Rivero Morfin PJ et al.	—	2024	→
A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome.	Liu X et al.	—	2024	→
Ahnak in the prefrontal cortex mediates behavioral correlates of stress resilience and rapid antidepressant action in mice.	Bhatti DL et al.	—	2024	→
Analysis of clinical studies on clozapine from 2012-2022.	Freibüchler A et al.	—	2024	→
Asian-European differentiation of schizophrenia-associated genes driven by admixture and natural selection.	Chen S et al.	—	2024	→
A splice acceptor variant in RGS6 associated with intellectual disability, microcephaly, and cataracts disproportionately promotes expression of a subset of RGS6 isoforms.	Ahlers-Dannen KE et al.	—	2024	→
Association of 11 variants of the dopaminergic and cognitive pathways genes with major depression, schizophrenia and bipolar disorder in the Pakistani population.	Nasir Hashmi A et al.	—	2024	→
Association of CACNA1C polymorphisms (rs1006737, rs4765905, rs2007044) with schizophrenia: A meta-analysis and trial sequential analysis.	Sarangi S et al.	—	2024	→
Association of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging.	Wu CS et al.	—	2024	→
Associations between ADHD and risk of six psychiatric disorders: a Mendelian randomization study.	Guo Y et al.	—	2024	→
Associations between polygenic liability to psychopathology and non-suicidal versus suicidal self-injury.	Edwards AC et al.	—	2024	→
Association Study of Serotonin 1A Receptor Gene, Personality, and Anxiety in Women with Alcohol Use Disorder.	Boroń A et al.	—	2024	→
Behaviour-correlated profiles of cerebellar-cerebral functional connectivity observed in independent neurodevelopmental disorder cohorts.	Morgado F et al.	—	2024	→
Bipolar disorder and Lewy body dementia: case report and literature review.	Nakamura S et al.	—	2024	→
Cacna1c deficiency in forebrain glutamatergic neurons alters behavior and hippocampal plasticity in female mice.	Loganathan S et al.	—	2024	→
Causal relationships between neuropsychiatric disorders and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study.	Wang S et al.	—	2024	→
Clinical and personal predictors of functioning in affective disorders: Exploratory results from baseline and 6-month follow-up of a randomised controlled trial.	Schwarz R et al.	—	2024	→
Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation.	van der Meer D et al.	—	2024	→
Comprehensive immunoprofiling of neurodevelopmental disorders suggests three distinct classes based on increased neurogenesis, Th-1 polarization or IL-1 signaling.	Sreenivas N et al.	—	2024	→
Cortical gradient perturbation in attention deficit hyperactivity disorder correlates with neurotransmitter-, cell type-specific and chromosome- transcriptomic signatures.	Chen Z et al.	—	2024	→
Developmental psychopathology as a meta-paradigm: From zero-sum science to epistemological pluralism in theory and research.	Beauchaine TP	—	2024	→
Development of the psychopathological vulnerability index for screening at-risk youths: a Rasch model approach.	Liao Y et al.	—	2024	→
Discrimination between healthy participants and people with panic disorder based on polygenic scores for psychiatric disorders and for intermediate phenotypes using machine learning.	Ohi K et al.	—	2024	→
Disease burden of mental disorders among children and adolescents considering both co-morbidities and suicide in Northeastern China.	Li Y et al.	—	2024	→
Diverse Roles of the LINC Complex in Cellular Function and Disease in the Nervous System.	Kuwako KI et al.	—	2024	→
Dynamic structure-function coupling across three major psychiatric disorders.	Zhang Z et al.	—	2024	→
Effects of CACNA1C and ANK3 on cognitive function in patients with bipolar disorder.	Yang Y et al.	—	2024	→
Elucidating multifinal and equifinal pathways to developmental disorders by constructing real-world neurorobotic models.	Idei H et al.	—	2024	→
Epidemiological and Genetic Analyses of Schizophrenia and Breast Cancer.	Tang M et al.	—	2024	→
Epilepsy and psychiatric comorbidities: A bidirectional mendelian randomization study.	Chu H et al.	—	2024	→
Exploring functional dysconnectivity in schizophrenia: alterations in eigenvector centrality mapping and insights into related genes from transcriptional profiles.	Ji Y et al.	—	2024	→
Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of qualitative evidence.	McCartan CJ et al.	—	2024	→
Gene-environment interactions in the influence of maternal education on adolescent neurodevelopment using ABCD study.	Shi R et al.	—	2024	→
Generation and transcriptomic characterization of MIR137 knockout miniature pig model for neurodevelopmental disorders.	Xu S et al.	—	2024	→
Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci.	Lori A et al.	—	2024	→
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture.	Morey RA et al.	—	2024	→
Higher Blood-brain barrier permeability in patients with major depressive disorder identified by DCE-MRI imaging.	Shang B et al.	—	2024	→
Identification of a Predictive Model for Schizophrenia Based on SNPs in a Chinese Population.	Yang Z et al.	—	2024	→
Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation.	Park J et al.	—	2024	→
Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale.	Hoang N et al.	—	2024	→
Interleukin-23 levels in umbilical cord blood are associated with neurodevelopmental trajectories in infancy.	Asaka MK et al.	—	2024	→
Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 Analogs.	Modestino EJ et al.	—	2024	→
Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder.	Song J et al.	—	2024	→
Mapping the structure of biomarkers in autism spectrum disorder: a review of the most influential studies.	Jin F et al.	—	2024	→
Massively parallel characterization of regulatory elements in the developing human cortex.	Deng C et al.	—	2024	→
Meta-analysis of 46,000 germline de novo mutations linked to human inherited disease.	Lopes-Marques M et al.	—	2024	→
Metabolic Insights into Neuropsychiatric Illnesses and Ketogenic Therapies: A Transcriptomic View.	Sahay S et al.	—	2024	→
Multi-polygenic scores in psychiatry: From disorder specific to transdiagnostic perspectives.	Shi Y et al.	—	2024	→
Neurophysiological profiles of patients with bipolar disorders as probed with transcranial magnetic stimulation: A systematic review.	Taniguchi K et al.	—	2024	→
Neuropsychiatric disorders, chronotype and sleep: A narrative review of GWAS findings and the application of Mendelian randomization to investigate causal relationships.	Crinion S et al.	—	2024	→
Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function.	Li Z et al.	—	2024	→
Opto-chemogenetic inhibition of L-type Ca<sub>V</sub>1 channels in neurons through a membrane-assisted molecular linkage.	Geng J et al.	—	2024	→
Parental mental disorders and ages of onset of severe mental disorders in offspring: A nationwide family-link study.	Ching PY et al.	—	2024	→
Pathophysiological Mechanisms of Psychosis-Induced Atrial Fibrillation: The Links between Mental Disorder and Arrhythmia.	Chen PH et al.	—	2024	→
Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.	Nuñez NA et al.	—	2024	→
Pleiotropy, epistasis and the genetic architecture of quantitative traits.	Mackay TFC et al.	—	2024	→
Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder.	LaBianca S et al.	—	2024	→
Post-transcriptional dysregulation in autism, schizophrenia, and bipolar disorder.	Wang Y et al.	—	2024	→
Progress and trends of research on mineral elements for depression.	Gao B et al.	—	2024	→
Psychotic symptoms associated increased CpG methylation of metabotropic glutamate receptor 8 gene in Chinese Han males with schizophrenia and methamphetamine induced psychotic disorder: a longitudinal study.	Dong H et al.	—	2024	→
Rare and common variants associated with alcohol consumption identify a conserved molecular network.	Leger BS et al.	—	2024	→
Resolving heterogeneity in schizophrenia, bipolar I disorder, and attention-deficit/hyperactivity disorder through individualized structural covariance network analysis.	Niu L et al.	—	2024	→
Schizophrenia risk proteins ZNF804A and NT5C2 interact in cortical neurons.	Aabdien A et al.	—	2024	→
Shared and distinct electroencephalogram microstate abnormalities across schizophrenia, bipolar disorder, and depression.	Xue R et al.	—	2024	→
Shared and Distinct White Matter Alterations in Major Depression and Bipolar Disorder: A Systematic Review and Meta-Analysis.	Xu Y et al.	—	2024	→
Single-cell genomics and regulatory networks for 388 human brains.	Emani PS et al.	—	2024	→
Susceptibility to Treatment-Resistant Depression Within Families.	Cheng CM et al.	—	2024	→
Temperament Traits in Pediatric Obsessive-Compulsive Disorder in Relation to Tourette Syndrome and Attention-Deficit Hyperactivity Disorder.	Cheng JS et al.	—	2024	→
The detect consensus report on Attention Deficit/Hyperactivity Disorder and its management among Turkish children and adolescents (Detect: consensus report on ADHD among Turkish youth).	Öğütlü H et al.	—	2024	→
The function of <i>Mef2c</i> toward the development of excitatory and inhibitory cortical neurons.	Ward C et al.	—	2024	→
The structure of psychiatric comorbidity without selection and assortative mating.	Ayorech Z et al.	—	2024	→
Transcriptional patterns of the cortical Morphometric Inverse Divergence in first-episode, treatment-naïve early-onset schizophrenia.	Yao G et al.	—	2024	→
Transcription factor 4 expression in the developing non-human primate brain: a comparative analysis with the mouse brain.	Burette AC et al.	—	2024	→
Transcriptome analysis to explore the mechanism of downregulated TNIK influencing the effect of risperidone.	Yuan R et al.	—	2024	→
Understanding copy number variations through their genes: a molecular view on 16p11.2 deletion and duplication syndromes.	Leone R et al.	—	2024	→
Understanding psychotic-like experiences in children in the context of dimensions of psychological problems.	Jeong HJ et al.	—	2024	→
Understanding the link between different types of maternal diabetes and the onset of autism spectrum disorders.	Shao W et al.	—	2024	→
Unique transcriptional signatures correlate with behavioral and psychological symptom domains in Alzheimer's disease.	Fisher DW et al.	—	2024	→
Using Dispositions to Understand Otherwise Intractable Causal Pathways to Psychological Problems During Childhood and Adolescence.	Lahey BB	—	2024	→
Validation of Wistar-Kyoto rats kept in solitary housing as an animal model for depression using voxel-based morphometry.	Yoshii T et al.	—	2024	→
A Cross-Sectional Study of the Neuropsychiatric Phenotype of CACNA1C-Related Disorder.	Levy RJ et al.	—	2023	→
A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders.	Lombardi L et al.	—	2023	→
Animal Models of Childhood Exposure to Lead or Manganese: Evidence for Impaired Attention, Impulse Control, and Affect Regulation and Assessment of Potential Therapies.	Smith DR et al.	—	2023	→
Antihypertensive drugs and brain function: mechanisms underlying therapeutically beneficial and harmful neuropsychiatric effects.	Carnovale C et al.	—	2023	→
A pilot pharmacogenetic study of calcium channel blocker treatment of bipolar mania.	Li M et al.	—	2023	→
Applications of Polygenic Risk Scores in Psychiatric Genetics.	Mao Q et al.	—	2023	→
A Sex-Dependent Association Between Doxycycline Use and Development of Schizophrenia.	de Witte LD et al.	—	2023	→
A sex-specific genome-wide association study of depression phenotypes in UK Biobank.	Silveira PP et al.	—	2023	→
Associated Genetics and Connectomic Circuitry in Schizophrenia and Bipolar Disorder.	Wei Y et al.	—	2023	→
A transdiagnostic network for psychiatric illness derived from atrophy and lesions.	Taylor JJ et al.	—	2023	→
BDNF Levels According to Variations in the CACNA1C Gene: Sex-Based Disparity.	Bastos CR et al.	—	2023	→
Brain-derived neurotrophic factor (BDNF) epigenomic modifications and brain-related phenotypes in humans: A systematic review.	Treble-Barna A et al.	—	2023	→
CACNA1C-Related Channelopathies.	Herold KG et al.	—	2023	→
Children and adolescents with attention deficit hyperactivity disorder and autism spectrum disorder share distinct microbiota compositions.	Bundgaard-Nielsen C et al.	—	2023	→
Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits.	Vysotskiy M et al.	—	2023	→
Common and Distinct Functional Connectivity of the Orbitofrontal Cortex in Depression and Schizophrenia.	Huang H et al.	—	2023	→
Connecting Dots between Mitochondrial Dysfunction and Depression.	Khan M et al.	—	2023	→
Cortical profiles of numerous psychiatric disorders and normal development share a common pattern.	Cao Z et al.	—	2023	→
Cortical structural changes of morphometric similarity network in early-onset schizophrenia correlate with specific transcriptional expression patterns.	Yao G et al.	—	2023	→
Cross-disorder GWAS meta-analysis of endocannabinoid DNA variations in major depressive disorder, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorder, and schizophrenia.	Kim HK et al.	—	2023	→
Current status, challenges and future prospects in computational psychiatry: a narrative review.	Vasilchenko KF et al.	—	2023	→
Delineation of complex gene expression patterns in single cell RNA-seq data with ICARUS v2.0.	Jiang A et al.	—	2023	→
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood.	Askeland RB et al.	—	2023	→
Differences in intracellular protein levels in monocytes and CD4<sup>+</sup> lymphocytes between bipolar depressed patients and healthy controls: A pilot study with tyramine-based signal-amplified flow cytometry.	Gao K et al.	—	2023	→
Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and bipolar disorder.	Kathuria A et al.	—	2023	→
Dynamic functional connectivity in schizophrenia and bipolar disorder: A review of the evidence and associations with psychopathological features.	Cattarinussi G et al.	—	2023	→
Environmental Factors in the Etiology of Mental Disorders in the Czech Republic.	Hosak L et al.	—	2023	→
Epigenetics in Neurological and Psychiatric Disorders: A Comprehensive Review of Current Understanding and Future Perspectives.	Grezenko H et al.	—	2023	→
Examining the shared etiology of psychopathology with genome-wide association studies.	Mallard TT et al.	—	2023	→
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure.	Hollestein V et al.	—	2023	→
Exploring the Hypothesis of a Schizophrenia and Bipolar Disorder Continuum: Biological, Genetic and Pharmacologic Data.	de Sousa TR et al.	—	2023	→
Fetal inflammatory response and risk for psychiatric disorders.	Gibson B et al.	—	2023	→
Formulating treatment of major psychiatric disorders: algorithm targets the dominantly affected brain cell-types.	Fessel J	—	2023	→
Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes.	Ribasés M et al.	—	2023	→
Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration.	Austin-Zimmerman I et al.	—	2023	→
Genome-Wide Association Study of Age-Related Macular Degeneration Reveals 2 New Loci Implying Shared Genetic Components with Central Serous Chorioretinopathy.	Akiyama M et al.	—	2023	→
graph-GPA 2.0: improving multi-disease genetic analysis with integration of functional annotation data.	Deng Q et al.	—	2023	→
Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images.	Zhao B et al.	—	2023	→
How can childhood maltreatment affect post-traumatic stress disorder in adult: Results from a composite null hypothesis perspective of mediation analysis.	Xu H et al.	—	2023	→
How can the DSM-5 alternative model of personality disorders advance understanding of depression?	Vittengl JR et al.	—	2023	→
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders.	Karadag N et al.	—	2023	→
Immune synaptopathies: how maternal immune activation impacts synaptic function during development.	Matteoli M et al.	—	2023	→
Inborn Errors of Purine Salvage and Catabolism.	Camici M et al.	—	2023	→
Is adjustment disorder genetically correlated with depression, anxiety, or risk-tolerant personality trait?	Ohi K et al.	—	2023	→
Longitudinal Factor Structure of the Brief Psychiatric Rating Scale Among Incident Cases of Schizophrenia Attending a Nigerian Hospital.	Onu JU et al.	—	2023	→
L-type calcium channels and neuropsychiatric diseases: Insights into genetic risk variant-associated genomic regulation and impact on brain development.	Baker MR et al.	—	2023	→
Mapping autism's research landscape: trends in autism screening and its alignment with sustainable development goals.	Nedungadi P et al.	—	2023	→
Maternal prenatal depression is associated with dysregulation over the first five years of life moderated by child polygenic risk for comorbid psychiatric problems.	Babineau V et al.	—	2023	→
Mediation Effects of Social Cognition on the Relationship between Neurocognition and Social Functioning in Major Depressive Disorder and Schizophrenia Spectrum Disorders.	Uchino T et al.	—	2023	→
Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study.	Senner F et al.	—	2023	→
Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression.	Sokolov AV et al.	—	2023	→
Multi-omics data integration methods and their applications in psychiatric disorders.	Sathyanarayanan A et al.	—	2023	→
New insights into the structure and function of CNNM proteins.	Chen YS et al.	—	2023	→
Noncoding transcripts are linked to brain resting-state activity in non-human primates.	Wang W et al.	—	2023	→
Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD.	Sveinsdóttir HS et al.	—	2023	→
Oral Health Status of Outpatients with Schizophrenia in Ankara, Türkiye: A Descriptive Study.	Karaman E et al.	—	2023	→
Peripheral S100B Protein Levels in Five Major Psychiatric Disorders: A Systematic Review.	Kozlowski T et al.	—	2023	→
"P factor" could open an important window on core attributes of mental health maladies.	Adam D	—	2023	→
Phase-and disorder-specific differences in peripheral metabolites of the kynurenine pathway in major depression, bipolar affective disorder and schizophrenia.	Brum M et al.	—	2023	→
Pleiotropic Association of CACNA1C Variants With Neuropsychiatric Disorders.	Wang Z et al.	—	2023	→
Polygenic risk scores of lithium response and treatment resistance in major depressive disorder.	Xiong Y et al.	—	2023	→
Potential application of elastic nets for shared polygenicity detection with adapted threshold selection.	John M et al.	—	2023	→
Predicting eating disorder and anxiety symptoms using disorder-specific and transdiagnostic polygenic scores for anorexia nervosa and obsessive-compulsive disorder.	Yilmaz Z et al.	—	2023	→
Probing the overarching continuum theory: data-driven phenotypic clustering of children with ASD or ADHD.	Deserno MK et al.	—	2023	→
Research hotspots and trends in the relationship between genetics and major depressive disorder: A scientometric analysis from 2003 to 2023.	Zhao Z et al.	—	2023	→
Resting-state brain functional alterations and their genetic mechanisms in drug-naive first-episode psychosis.	Li Q et al.	—	2023	→
Sex Significantly Impacts the Function of Major Depression-Linked Variants In Vivo.	Mulvey B et al.	—	2023	→
Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank.	Roelfs D et al.	—	2023	→
Shared genetics of psychiatric disorders and type 2 diabetes:a large-scale genome-wide cross-trait analysis.	Ding H et al.	—	2023	→
Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage composite likelihood.	Ting BW et al.	—	2023	→
Social-Emotional and Behavioural Difficulties in Children with Neurodevelopmental Disorders: Emotion Perception in Daily Life and in a Formal Assessment Context.	Löytömäki J et al.	—	2023	→
The Cerebellum Gets Social: Evidence from an Exploratory Study of Cerebellar, Neurodevelopmental, and Psychiatric Disorders.	Olivito G et al.	—	2023	→
The developmental interplay between the p-factor of psychopathology and the g-factor of intelligence from age 7 through 16 years.	von Stumm S et al.	—	2023	→
The genetic relationships between brain structure and schizophrenia.	Stauffer EM et al.	—	2023	→
The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder.	Namkung H et al.	—	2023	→
The moderation of the genetic risk for alcohol and drug use disorders in a Swedish national sample by the genetic aptitude for educational attainment.	Kendler KS et al.	—	2023	→
Transcriptional signatures of the cortical morphometric similarity network gradient in first-episode, treatment-naive major depressive disorder.	Xue K et al.	—	2023	→
Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing.	Grotzinger AD et al.	—	2023	→
Understanding the relationship between asthma and autism spectrum disorder: a population-based family and twin study.	Gong T et al.	—	2023	→
Use of big data and machine learning algorithms to extract possible treatment targets in neurodevelopmental disorders.	Malik MA et al.	—	2023	→
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.	Hsu YH et al.	—	2023	→
Wildtype peers rescue social play and 50-kHz ultrasonic vocalization deficits in juvenile female <i>Cacna1c</i> heterozygous rats.	Bogdan R et al.	—	2023	→
Abnormal RasGRP1 Expression in the Post-Mortem Brain and Blood Serum of Schizophrenia Patients.	De Rosa A et al.	—	2022	→
A comprehensive comparison of multilocus association methods with summary statistics in genome-wide association studies.	Shao Z et al.	—	2022	→
Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences.	Gall-Duncan T et al.	—	2022	→
A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions.	Nudel R et al.	—	2022	→
A family study of symbolic learning and synaptic plasticity in autism spectrum disorder.	Granerud G et al.	—	2022	→
A matter of space and time: Emerging roles of disease-associated proteins in neural development.	Panagiotakos G et al.	—	2022	→
An opportunity for primary prevention research in psychotic disorders.	Gershon ES et al.	—	2022	→
A novel longitudinal clustering approach to psychopathology across diagnostic entities in the hospital-based PsyCourse study.	Schulte EC et al.	—	2022	→
A psychiatric disorder risk polymorphism of ITIH3 is associated with multiple neuroimaging phenotypes in young healthy adults.	Takeuchi H et al.	—	2022	→
Association between type 1 diabetes and neurodevelopmental disorders in children and adolescents: A systematic review and meta-analysis.	Xie XN et al.	—	2022	→
Association of <i>PPP1R1B</i> polymorphisms with working memory in healthy Han Chinese adults.	Ma H et al.	—	2022	→
Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown.	Ahrens KF et al.	—	2022	→
A Systematic Review of Genetic Polymorphisms Associated with Bipolar Disorder Comorbid to Substance Abuse.	de Marco A et al.	—	2022	→
A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia.	McGuinness AJ et al.	—	2022	→
Back to the Future: The Role of Infections in Psychopathology. Focus on OCD.	Della Vecchia A et al.	—	2022	→
Birth Weight and Childhood Psychopathology in the ABCD Cohort: Association is Strongest for Attention Problems and is Moderated by Sex.	Dooley N et al.	—	2022	→
Brain transcriptomic profiling reveals common alterations across neurodegenerative and psychiatric disorders.	Sadeghi I et al.	—	2022	→
CACNA1C (Ca<sub>V</sub>1.2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics and pharmacoepidemiology.	Harrison PJ et al.	—	2022	→
Calcium and activity-dependent signaling in the developing cerebral cortex.	Arjun McKinney A et al.	—	2022	→
Cancer risk in patients with bipolar disorder and unaffected siblings of such patients: A nationwide population-based study.	Chen MH et al.	—	2022	→
Cell-type-specific genes associated with cortical structural abnormalities in pediatric bipolar disorder.	Lei W et al.	—	2022	→
Characterization of Hemodynamic Alterations in Schizophrenia and Bipolar Disorder and Their Effect on Resting-State fMRI Functional Connectivity.	Yan W et al.	—	2022	→
Characterizing the polygenic overlaps of bipolar disorder subtypes with schizophrenia and major depressive disorder.	Li Z et al.	—	2022	→
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation.	Hindley G et al.	—	2022	→
Childhood Trauma May Increase Risk of Psychosis and Mood Disorder in Genetically High-risk Children and Adolescents by Enhancing the Accumulation of Risk Indicators.	Berthelot N et al.	—	2022	→
Circulating microRNA miR-137 as a stable biomarker for methamphetamine abstinence.	Kim B et al.	—	2022	→
Classifying major mental disorders genetically.	Cao H et al.	—	2022	→
Common effects of bipolar disorder medications on expression quantitative trait loci genes.	Truong TT et al.	—	2022	→
Common variants contribute to intrinsic human brain functional networks.	Zhao B et al.	—	2022	→
Consensus on potential biomarkers developed for use in clinical tests for schizophrenia.	Lin P et al.	—	2022	→
Contribution of <i>CACNA1H</i> Variants in Autism Spectrum Disorder Susceptibility.	Viggiano M et al.	—	2022	→
Cross-Disorder Analysis of De Novo Mutations in Neuropsychiatric Disorders.	Li K et al.	—	2022	→
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings.	Cheon EJ et al.	—	2022	→
Culture and psychopathology: An attempt at reconsidering the role of social learning.	Fonagy P et al.	—	2022	→
Cytosolic peptides encoding Ca<sub>V</sub>1 C-termini downregulate the calcium channel activity-neuritogenesis coupling.	Yang Y et al.	—	2022	→
Deletion of the voltage-gated calcium channel, Ca<sub>V</sub> 1.3, causes deficits in motor performance and associative learning.	Lauffer M et al.	—	2022	→
Disentangling the associations between past childhood adversity and psychopathology during the COVID-19 pandemic: The mediating roles of specific pandemic stressors and coping strategies.	Jernslett M et al.	—	2022	→
Disrupted <i>Cacna1c</i> gene expression perturbs spontaneous Ca<sup>2+</sup> activity causing abnormal brain development and increased anxiety.	Smedler E et al.	—	2022	→
Editorial: Brain cells' compensatory mechanisms in response to disease risk factors.	Kim Y et al.	—	2022	→
Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity.	Schmitt S et al.	—	2022	→
Effects of prenatal nutrient supplementation and early life exposures on neurodevelopment at age 10: a randomised controlled trial - the COPSYCH study protocol.	Mohammadzadeh P et al.	—	2022	→
Effects of psychosis-associated genetic markers on brain volumetry: a systematic review of replicated findings and an independent validation.	Vouga Ribeiro N et al.	—	2022	→
Encore: Behavioural animal models of stress, depression and mood disorders.	Petković A et al.	—	2022	→
ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.	Kochunov P et al.	—	2022	→
Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism.	Schendel D et al.	—	2022	→
Evidence of genetic overlap and causal relationships between blood-based biochemical traits and human cortical anatomy.	Kiltschewskij DJ et al.	—	2022	→
Eye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjects.	St Clair D et al.	—	2022	→
Familial coaggregation of major psychiatric disorders in first-degree relatives of individuals with autism spectrum disorder: a nationwide population-based study.	Wang HE et al.	—	2022	→
Further validation of the Cognitive Biases Questionnaire for psychosis.	Samson C et al.	—	2022	→
Genetic Predisposition to Schizophrenia and Depressive Disorder Comorbidity.	Shnayder NA et al.	—	2022	→
Genetics of age-at-onset in major depression.	Harder A et al.	—	2022	→
Genetic Variants Associated With Resilience in Human and Animal Studies.	Cahill S et al.	—	2022	→
Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders.	Gunturkun MH et al.	—	2022	→
Genomics, convergent neuroscience and progress in understanding autism spectrum disorder.	Willsey HR et al.	—	2022	→
Gut dysbiosis in severe mental illness and chronic fatigue: a novel trans-diagnostic construct? A systematic review and meta-analysis.	Safadi JM et al.	—	2022	→
Half a century of research on Attention-Deficit/Hyperactivity Disorder: A scientometric study.	Cortese S et al.	—	2022	→
Higher scores on autonomic symptom scales in pediatric patients with neurodevelopmental disorders of known genetic etiology.	DiCriscio AS et al.	—	2022	→
High polygenic predisposition for ADHD and a greater risk of all-cause mortality: a large population-based longitudinal study.	Ajnakina O et al.	—	2022	→
How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID).	Kennedy HL et al.	—	2022	→
Identification of ultra-rare disruptive variants in voltage-gated calcium channel-encoding genes in Japanese samples of schizophrenia and autism spectrum disorder.	Wang C et al.	—	2022	→
Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing.	Wang T et al.	—	2022	→
Identifying pleiotropic genes for major psychiatric disorders with GWAS summary statistics using multivariate adaptive association tests.	Wang Y et al.	—	2022	→
Identifying transdiagnostic biological subtypes across schizophrenia, bipolar disorder, and major depressive disorder based on lipidomics profiles.	Tao S et al.	—	2022	→
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis.	Werner MCF et al.	—	2022	→
Integrated co-expression network analysis uncovers novel tissue-specific genes in major depressive disorder and bipolar disorder.	Han M et al.	—	2022	→
Integrative Functional Genomic Analysis in Multiplex Autism Families from Kazakhstan.	Perfilyeva A et al.	—	2022	→
Investigating the molecular genetic, genomic, brain structural, and brain functional correlates of latent transdiagnostic dimensions of psychopathology across the lifespan: Protocol for a systematic review and meta-analysis of cross-sectional and longitudinal studies in the general population.	Hoy N et al.	—	2022	→
Leveraging pleiotropy for joint analysis of genome-wide association studies with per trait interpretations.	Taraszka K et al.	—	2022	→
L-Type Calcium Channels Contribute to Ethanol-Induced Aberrant Tangential Migration of Primordial Cortical GABAergic Interneurons in the Embryonic Medial Prefrontal Cortex.	Lee SM et al.	—	2022	→
Maternal Depressive Symptoms Predict General Liability in Child Psychopathology.	Swales DA et al.	—	2022	→
Maternal Schizophrenia and the Risk of a Childhood Chronic Condition.	Vigod SN et al.	—	2022	→
Mendelian Randomization Research on the Relationship Between Rheumatoid Arthritis and Systemic Lupus Erythematosus and the Risk of Autistic Spectrum Disorder.	Lee YH et al.	—	2022	→
Meta-analytical transdiagnostic neural correlates in common pediatric psychiatric disorders.	Dugré JR et al.	—	2022	→
Molecular and Cellular Adaptations in Hippocampal Parvalbumin Neurons Mediate Behavioral Responses to Chronic Social Stress.	Bhatti DL et al.	—	2022	→
Neural Correlates of the Risk for Schizophrenia and Bipolar Disorder: A Meta-analysis of Structural and Functional Neuroimaging Studies.	Cattarinussi G et al.	—	2022	→
Neuronal deletion of Ca<sub>V</sub>1.2 is associated with sex-specific behavioral phenotypes in mice.	Klomp AJ et al.	—	2022	→
Niacin mitigates blood-brain barrier tight junctional proteins dysregulation and cerebral inflammation in ketamine rat model of psychosis: Role of GPR109A receptor.	Ibrahim WW et al.	—	2022	→
Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants.	Zhang R et al.	—	2022	→
Patterns of Convergence and Divergence Between Bipolar Disorder Type I and Type II: Evidence From Integrative Genomic Analyses.	Huang Y et al.	—	2022	→
Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives.	Jiao S et al.	—	2022	→
Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging.	Wang C et al.	—	2022	→
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study.	Engh JA et al.	—	2022	→
Plasma proteomic signature of major depressive episode in the elderly.	Silva-Costa LC et al.	—	2022	→
Polygenic risk scores for schizophrenia and major depression are associated with socio-economic indicators of adversity in two British community samples.	Machlitt-Northen S et al.	—	2022	→
Predicting adolescent alcohol and other drug problems using electronic health records data.	Chi FW et al.	—	2022	→
Protein Profiling of RGS6, a Pleiotropic Gene Implicated in Numerous Neuropsychiatric Disorders, Reveals Multi-Isoformic Expression and a Novel Brain-Specific Isoform.	Ahlers-Dannen KE et al.	—	2022	→
Psychiatric manifestations of rare variation in medically actionable genes: a PheWAS approach.	Feng YA et al.	—	2022	→
Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders.	Truong TTT et al.	—	2022	→
Resting-state functional connectivity of salience network in schizophrenia and depression.	Huang H et al.	—	2022	→
S100A10 and its binding partners in depression and antidepressant actions.	Chen MX et al.	—	2022	→
Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume.	de Zwarte SMC et al.	—	2022	→
Shank promotes action potential repolarization by recruiting BK channels to calcium microdomains.	Gao L et al.	—	2022	→
Shared components of heritability across genetically correlated traits.	Ballard JL et al.	—	2022	→
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets.	Aoki R et al.	—	2022	→
Shared genetics between autism spectrum disorder and attention-deficit/hyperactivity disorder and their association with extraversion.	Baranova A et al.	—	2022	→
Shared Transdiagnostic Neuroanatomical Signatures Across First-episode Patients with Major Psychiatric Diseases and Individuals at Familial Risk.	Jia L et al.	—	2022	→
Small Molecules as Modulators of Voltage-Gated Calcium Channels in Neurological Disorders: State of the Art and Perspectives.	Lanzetti S et al.	—	2022	→
Structural magnetic resonance imaging findings in severe mental disorders adult inpatients: A systematic review.	Brenner AM et al.	—	2022	→
SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence.	Kim B et al.	—	2022	→
Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders.	Akingbuwa WA et al.	—	2022	→
The ANC-1 (Nesprin-1/2) organelle-anchoring protein functions through mitochondria to polarize axon growth in response to SLT-1.	Fischer NC et al.	—	2022	→
The Ca<sub>V</sub>1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca<sup>2+</sup> channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome.	Sanderson JL et al.	—	2022	→
The Current Progress of Psychiatric Genomics.	Nishioka M	—	2022	→
The hallmarks of autism.	Crespi BJ	—	2022	→
The Involvement of Long Non-coding RNA and Messenger RNA Based Molecular Networks and Pathways in the Subacute Phase of Traumatic Brain Injury in Adult Mice.	Yang Z et al.	—	2022	→
The next 10 years of behavioural genomic research.	Plomin R	—	2022	→
The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores.	Page ML et al.	—	2022	→
The SFT2D2 gene is associated with the autoimmune pathology of schizophrenia in a Chinese population.	Liu D et al.	—	2022	→
The voltage-gated Ca2+ channel subunit α2δ-4 regulates locomotor behavior and sensorimotor gating in mice.	Klomp A et al.	—	2022	→
Towards the understanding of state-independent neural traits underlying psychiatric disorders.	Cao H	—	2022	→
Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content.	Papes F et al.	—	2022	→
Type 1 diabetes mellitus and risks of major psychiatric disorders: A nationwide population-based cohort study.	Chen MH et al.	—	2022	→
Understanding psychiatric illness through natural language processing (UNDERPIN): Rationale, design, and methodology.	Kishimoto T et al.	—	2022	→
Using animal models for the studies of schizophrenia and depression: The value of translational models for treatment and prevention.	Uliana DL et al.	—	2022	→
Using big data of genetics, health claims, and brain imaging to challenge the categorical classification in mental illness.	Su TP et al.	—	2022	→
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group.	Ching CRK et al.	—	2022	→
White Matter Alterations in Depressive Disorder.	He E et al.	—	2022	→
Working memory and reaction time variability mediate the relationship between polygenic risk and ADHD traits in a general population sample.	Moses M et al.	—	2022	→
A Biased Perspective on Brain Imaging of ADHD.	Castellanos FX	—	2021	→
A biomarker-based study of prenatal smoking exposure and autism in a Finnish national birth cohort.	Cheslack-Postava K et al.	—	2021	→
A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics.	Lu H et al.	—	2021	→
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A fundamental distinction in early neural processing of implicit social interpretation in schizophrenia and bipolar disorder.	Madeira N et al.	—	2021	→
A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MTd2d3 and Mushroom Dendritic Spine Density.	Cai X et al.	—	2021	→
A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21.	Toma C et al.	—	2021	→
A longitudinal study of gene expression in first-episode schizophrenia; exploring relapse mechanisms by co-expression analysis in peripheral blood.	Gassó P et al.	—	2021	→
A meta-study on transcription factor networks in the suicidal brain.	Cabrera-Mendoza B et al.	—	2021	→
Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygenic scores.	Rao S et al.	—	2021	→
A Neurodevelopment Approach for a Transitional Model of Early Onset Schizophrenia.	De Berardis D et al.	—	2021	→
Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration.	Sasabayashi D et al.	—	2021	→
A polygenic resilience score moderates the genetic risk for schizophrenia.	Hess JL et al.	—	2021	→
"Apples and pears are similar, but still different things." Bipolar disorder and schizophrenia- discrete disorders or just dimensions ?	Grunze H et al.	—	2021	→
Assessing the validity of administrative health data for the identification of children and youth with autism spectrum disorder in Ontario.	Brooks JD et al.	—	2021	→
Association and Gene-Gene Interactions Study of Late-Onset Alzheimer's Disease in the Russian Population.	Bocharova A et al.	—	2021	→
A structural brain network of genetic vulnerability to psychiatric illness.	Taquet M et al.	—	2021	→
Autism and mood disorders.	Oakley B et al.	—	2021	→
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.	Andlauer TFM et al.	—	2021	→
Brain Organoids: Filling the Need for a Human Model of Neurological Disorder.	Jalink P et al.	—	2021	→
Characterization of six CaMKIIα variants found in patients with schizophrenia.	Brown CN et al.	—	2021	→
Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility.	Hartl CL et al.	—	2021	→
Common and Distinct Alterations of Cognitive Function and Brain Structure in Schizophrenia and Major Depressive Disorder: A Pilot Study.	Ma M et al.	—	2021	→
Comorbid major depression in first-episode drug-naïve patients with schizophrenia: Analysis of the Depression in Schizophrenia in China (DISC) study.	Li Z et al.	—	2021	→
Comprehensive Integrative Analyses Identify TIGD5 rs75547282 as a Risk Variant for Autism Spectrum Disorder.	Xie X et al.	—	2021	→
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.	Byrne EM et al.	—	2021	→
Contextualizing genetic risk score for disease screening and rare variant discovery.	Zhou D et al.	—	2021	→
Convergence and Divergence in the Genetics of Psychiatric Disorders From Pathways to Developmental Stages.	Shohat S et al.	—	2021	→
Corpus callosum morphology in major mental disorders: a magnetic resonance imaging study.	Piras F et al.	—	2021	→
Correlation between cortical gene expression and resting-state functional network centrality in healthy young adults.	Zhu D et al.	—	2021	→
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures.	Li J et al.	—	2021	→
Cytokine Imbalance in Schizophrenia. From Research to Clinic: Potential Implications for Treatment.	Reale M et al.	—	2021	→
Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5.	Liu L et al.	—	2021	→
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders.	Akula N et al.	—	2021	→
Detecting local genetic correlations with scan statistics.	Guo H et al.	—	2021	→
Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity.	Clifton NE et al.	—	2021	→
Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy.	Verhoef E et al.	—	2021	→
Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons.	Runge K et al.	—	2021	→
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics.	Buch AM et al.	—	2021	→
DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia.	Hannon E et al.	—	2021	→
Dynamic Functional Connectivity Alterations and Their Associated Gene Expression Pattern in Autism Spectrum Disorders.	Ma L et al.	—	2021	→
Epigenome-wide study of brain DNA methylation following acute opioid intoxication.	Shu C et al.	—	2021	→
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder.	Valstad M et al.	—	2021	→
Exploring the biological role of postzygotic and germinal de novo mutations in ASD.	Alonso-Gonzalez A et al.	—	2021	→
Expression of the adult ADHD-associated gene <i>ADGRL3</i> is dysregulated by risk variants and environmental risk factors.	McNeill RV et al.	—	2021	→
Extra-synaptic modulation of GABA<sub>A</sub> and efficacy in bipolar disorder.	El-Mallakh RS et al.	—	2021	→
Family-based association study identifies SNAP25 as a susceptibility gene for autism in the Han Chinese population.	Wang Z et al.	—	2021	→
Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample.	Kendler KS et al.	—	2021	→
Functional patient-derived cellular models for neuropsychiatric drug discovery.	Lago SG et al.	—	2021	→
Future directions in personality pathology.	Fonagy P et al.	—	2021	→
Gender Differences in Misdiagnosis and Delayed Diagnosis among Adults with Autism Spectrum Disorder with No Language or Intellectual Disability.	Gesi C et al.	—	2021	→
Gene × environment interaction in major depressive disorder.	Zhao MZ et al.	—	2021	→
Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD.	Olde Loohuis LM et al.	—	2021	→
Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci.	Qu HQ et al.	—	2021	→
Genetic architectures of proximal and distal colorectal cancer are partly distinct.	Huyghe JR et al.	—	2021	→
Genetic factors influencing a neurobiological substrate for psychiatric disorders.	Andlauer TFM et al.	—	2021	→
Genetic neuroimaging of bipolar disorder: a systematic 2017-2020 update.	Janiri D et al.	—	2021	→
[Genetic risk factors and their influence on neural development in autism spectrum disorders].	Freitag CM et al.	—	2021	→
Genetics of eating disorders in the genome-wide era.	Watson HJ et al.	—	2021	→
Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene.	Gonda X et al.	—	2021	→
Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function.	Rathje M et al.	—	2021	→
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders.	Eum S et al.	—	2021	→
Genome-wide DNA methylation patterns associated with general psychopathology in children.	Rijlaarsdam J et al.	—	2021	→
Global Brain Flexibility During Working Memory Is Reduced in a High-Genetic-Risk Group for Schizophrenia.	Dimitriadis SI et al.	—	2021	→
Gut Microbiota, Probiotic Interventions, and Cognitive Function in the Elderly: A Review of Current Knowledge.	Białecka-Dębek A et al.	—	2021	→
Identification of a Risk Locus at 7p22.3 for Schizophrenia and Bipolar Disorder in East Asian Populations.	Li W et al.	—	2021	→
Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence.	Sun Y et al.	—	2021	→
Identification of Rare Mutations of Two Presynaptic Cytomatrix Genes <i>BSN</i> and <i>PCLO</i> in Schizophrenia and Bipolar Disorder.	Chen CH et al.	—	2021	→
Identifying and validating subtypes within major psychiatric disorders based on frontal-posterior functional imbalance via deep learning.	Chang M et al.	—	2021	→
<i>DRD1</i> and <i>DRD2</i> Receptor Polymorphisms: Genetic Neuromodulation of the Dopaminergic System as a Risk Factor for ASD, ADHD and ASD/ADHD Overlap.	Mariggiò MA et al.	—	2021	→
Increased Risk of ADHD at Short and Long Interpregnancy Intervals in a National Birth Cohort.	Cheslack-Postava K et al.	—	2021	→
Increased schizophrenia family history burden and reduced premorbid IQ in treatment-resistant schizophrenia: a Swedish National Register and Genomic Study.	Kowalec K et al.	—	2021	→
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.	Novikova G et al.	—	2021	→
Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Yao X et al.	—	2021	→
Interactions with PDZ proteins diversify voltage-gated calcium channel signaling.	Wang S et al.	—	2021	→
Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum.	Yang Z et al.	—	2021	→
Investigation of genetic loci shared between bipolar disorder and risk-taking propensity: potential implications for pharmacological interventions.	Pisanu C et al.	—	2021	→
Involvement of Rare Mutations of SCN9A, DPP4, ABCA13, and SYT14 in Schizophrenia and Bipolar Disorder.	Chen CH et al.	—	2021	→
Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders.	Searles Quick VB et al.	—	2021	→
Machine learning analysis of pregnancy data enables early identification of a subpopulation of newborns with ASD.	Caly H et al.	—	2021	→
Magnitude of Mendelian versus complex inheritance of rare disorders.	Chakravarti A	—	2021	→
Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders.	Ames JL et al.	—	2021	→
Mental distress through the prism of predictive processing theory.	Van de Cruys S et al.	—	2021	→
Metabolic Aspects of Adenosine Functions in the Brain.	Garcia-Gil M et al.	—	2021	→
Methodological and clinical challenges associated with biomarkers for psychiatric disease: A scoping review.	Kirkpatrick RH et al.	—	2021	→
Modeling human neuronal migration deficits in 3D.	Reiner O et al.	—	2021	→
mRNA Expression of the CUB and Sushi Multiple Domains 1 (<i>CSMD1</i>) and Its Serum Protein Level as Predictors for Psychosis in the Familial High-Risk Children and Young Adults.	Abd El Gayed EM et al.	—	2021	→
Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization.	Liu L et al.	—	2021	→
Mutations in DISC1 alter IP<sub>3</sub>R and voltage-gated Ca<sup>2+</sup> channel functioning, implications for major mental illness.	Rittenhouse AR et al.	—	2021	→
Neurobiological substrates of major psychiatry disorders: transdiagnostic associations between white matter abnormalities, neuregulin 1 and clinical manifestation.	Duan J et al.	—	2021	→
Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets.	Ľupták M et al.	—	2021	→
Origin of Sex-Biased Mental Disorders: An Evolutionary Perspective.	Singh RS et al.	—	2021	→
Oxidative Stress and the Pathophysiology and Symptom Profile of Schizophrenia Spectrum Disorders.	Murray AJ et al.	—	2021	→
Patterns of cilia gene dysregulations in major psychiatric disorders.	Alhassen W et al.	—	2021	→
Pleiotropic genetic influence on birth weight and childhood obesity.	Chatterjee S et al.	—	2021	→
Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders.	Lee PH et al.	—	2021	→
Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis.	Strom NI et al.	—	2021	→
Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals.	Kember RL et al.	—	2021	→
Polygenic Score for Smoking is associated with Externalizing Psychopathology and Disinhibited Personality Traits but not Internalizing Psychopathology in Adolescence.	Hicks BM et al.	—	2021	→
Preliminary evidence for timing abnormalities in the CNTNAP2 knockout rat.	Poulin CJ et al.	—	2021	→
Progress in mechanistically novel treatments for schizophrenia.	Neef J et al.	—	2021	→
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms.	Inserra A et al.	—	2021	→
Psychedelic Therapy's Transdiagnostic Effects: A Research Domain Criteria (RDoC) Perspective.	Kelly JR et al.	—	2021	→
Psychiatric Neural Networks and Precision Therapeutics by Machine Learning.	Komatsu H et al.	—	2021	→
Quantifying the contribution of Neanderthal introgression to the heritability of complex traits.	McArthur E et al.	—	2021	→
Quantitative Proteomic Approach for Discriminating Major Depressive Disorder and Bipolar Disorder by Multiple Reaction Monitoring-Mass Spectrometry.	Shin D et al.	—	2021	→
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder.	Wolfers T et al.	—	2021	→
Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas.	Arango C et al.	—	2021	→
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder.	Demontis D et al.	—	2021	→
Role of Ash1l in Tourette syndrome and other neurodevelopmental disorders.	Zhang C et al.	—	2021	→
Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications.	Wolking S et al.	—	2021	→
scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks.	Jin T et al.	—	2021	→
SERINC2 increases the risk of bipolar disorder in the Chinese population.	Yang D et al.	—	2021	→
Sex Difference in Comorbid Depression in First-Episode and Drug-Naive Patients With Schizophrenia: Baseline Results From the Depression in Schizophrenia in China Study.	Li Z et al.	—	2021	→
Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation.	Moore SR et al.	—	2021	→
Shared genetic architecture across psychiatric disorders.	Grotzinger AD	—	2021	→
Similarities and dissimilarities between psychiatric cluster disorders.	Smail MA et al.	—	2021	→
SNX29, a new susceptibility gene shared with major mental disorders in Han Chinese population.	Chen JH et al.	—	2021	→
Spatial Expression Pattern of ZNF391 Gene in the Brains of Patients With Schizophrenia, Bipolar Disorders or Major Depressive Disorder Identifies New Cross-Disorder Biotypes: A Trans-Diagnostic, Top-Down Approach.	Ren H et al.	—	2021	→
Stress impacts corticoamygdalar connectivity in an age-dependent manner.	Uliana DL et al.	—	2021	→
Targeting microglia L-type voltage-dependent calcium channels for the treatment of central nervous system disorders.	Hopp SC	—	2021	→
Targeting synaptic plasticity in schizophrenia: insights from genomic studies.	Mould AW et al.	—	2021	→
Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents.	Manfro AG et al.	—	2021	→
The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders.	Malhi GS et al.	—	2021	→
The Auditory Steady-State Response: Electrophysiological Index for Sensory Processing Dysfunction in Psychiatric Disorders.	Sugiyama S et al.	—	2021	→
The clinical characterization of the patient with primary psychosis aimed at personalization of management.	Maj M et al.	—	2021	→
The conserved ASTN2/BRINP1 locus at 9q33.1-33.2 is associated with major psychiatric disorders in a large pedigree from Southern Spain.	Pol-Fuster J et al.	—	2021	→
The Endocannabinoid System as Modulator of Exercise Benefits in Mental Health.	Amatriain-Fernández S et al.	—	2021	→
The Habenula in the Link Between ADHD and Mood Disorder.	Lee YA et al.	—	2021	→
The Importance of Common Currency Tasks in Translational Psychiatry.	Pike AC et al.	—	2021	→
Topologically associating domain boundaries that are stable across diverse cell types are evolutionarily constrained and enriched for heritability.	McArthur E et al.	—	2021	→
Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder.	Shephard E et al.	—	2021	→
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Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context.	Tamouza R et al.	—	2021	→
Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.	Cao X et al.	—	2021	→
Zebrafish Larvae Carrying a Splice Variant Mutation in cacna1d: A New Model for Schizophrenia-Like Behaviours?	Banono NS et al.	—	2021	→
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Abnormal information flow in postpartum depression: A resting-state functional magnetic resonance imaging study.	Mao N et al.	—	2020	→
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Alterations in Task-Related Brain Activation in Children, Adolescents and Young Adults at Familial High-Risk for Schizophrenia or Bipolar Disorder - A Systematic Review.	Johnsen LK et al.	—	2020	→
Altered hippocampal centrality and dynamic anatomical covariance of intracortical microstructure in first episode psychosis.	Makowski C et al.	—	2020	→
Analysis of KCNH2 and CACNA1C schizophrenia risk genes on EEG functional network modulation during an auditory odd-ball task.	Lubeiro A et al.	—	2020	→
An atlas of genetic correlations between psychiatric disorders and human blood plasma proteome.	Cheng S et al.	—	2020	→
[A new look at the genetics of neurocognitive deficits in schizophrenia].	Fedorenko OY et al.	—	2020	→
Antipsychotic <b>E</b>ffects on <b>C</b>ortical Morphology in <b>S</b>chizophrenia and <b>B</b>ipolar <b>D</b>isorders.	Feng R et al.	—	2020	→
A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between Type 2 Diabetes and Prostate Cancer.	Ray D et al.	—	2020	→
A process-based approach to psychological diagnosis and treatment:The conceptual and treatment utility of an extended evolutionary meta model.	Hayes SC et al.	—	2020	→
A review on neural network models of schizophrenia and autism spectrum disorder.	Lanillos P et al.	—	2020	→
Are youths with disruptive mood dysregulation disorder different from youths with major depressive disorder or persistent depressive disorder?	Benarous X et al.	—	2020	→
A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram.	Pedrazzoli M et al.	—	2020	→
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Associations of cigarette smoking with psychiatric disorders: evidence from a two-sample Mendelian randomization study.	Yuan S et al.	—	2020	→
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Attention-deficit hyperactivity disorder in school-age children in Gaborone, Botswana: Comorbidity and risk factors.	Olashore AA et al.	—	2020	→
Atypical lateralization in neurodevelopmental and psychiatric disorders: What is the role of stress?	Berretz G et al.	—	2020	→
Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology.	Cheroni C et al.	—	2020	→
Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease.	Hollander JA et al.	—	2020	→
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.	Amare AT et al.	—	2020	→
Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders.	Greene C et al.	—	2020	→
Brain Structure and Subclinical Symptoms: A Dimensional Perspective of Psychopathology in the Depression and Anxiety Spectrum.	Besteher B et al.	—	2020	→
Cacna1c Hemizygosity Results in Aberrant Fear Conditioning to Neutral Stimuli.	Moon AL et al.	—	2020	→
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Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders.	Dai Y et al.	—	2020	→
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Common neural and transcriptional correlates of inhibitory control underlie emotion regulation and memory control.	Liu W et al.	—	2020	→
Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese.	Jian X et al.	—	2020	→
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Computational Psychiatry Research Map (CPSYMAP): A New Database for Visualizing Research Papers.	Kato A et al.	—	2020	→
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Does single gene expression omnibus data mining analysis apply for only tumors and not mental illness? A preliminary study on bipolar disorder based on bioinformatics methodology.	You X et al.	—	2020	→
Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits.	Ghoshal A et al.	—	2020	→
Efficacy of cognitive-behavioral group therapy in patients at risk for serious mental illness presenting with subthreshold bipolar symptoms: Results from a prespecified interim analysis of a multicenter, randomized, controlled study.	Leopold K et al.	—	2020	→
Electrophysiological signatures of visual statistical learning in 3-month-old infants at familial and low risk for autism spectrum disorder.	Marin A et al.	—	2020	→
Evaluating the Impact of Nonrandom Mating: Psychiatric Outcomes Among the Offspring of Pairs Diagnosed With Schizophrenia and Bipolar Disorder.	Nordsletten AE et al.	—	2020	→
Evaluation of the relationships of the WBP1L gene with schizophrenia and the general psychopathology scale based on a case-control study.	Guan F et al.	—	2020	→
Evidence for a Cross-Talk Between Cytosolic 5'-Nucleotidases and AMP-Activated Protein Kinase.	Camici M et al.	—	2020	→
Evolutionary Ecological Model of Defence Activation Disorders Via the Marginal Value Theorem.	Park H	—	2020	→
Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks.	Lago SG et al.	—	2020	→
Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease.	Wamsley B et al.	—	2020	→
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Gene Regulatory Network of Dorsolateral Prefrontal Cortex: a Master Regulator Analysis of Major Psychiatric Disorders.	Bristot G et al.	—	2020	→
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Genetic and environmental factors of schizophrenia and autism spectrum disorder: insights from twin studies.	Imamura A et al.	—	2020	→
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Genome-wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders.	Price KM et al.	—	2020	→
Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort.	Osborne AJ et al.	—	2020	→
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.	Coleman JRI et al.	—	2020	→
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.	Zhou H et al.	—	2020	→
GWAS SNPs Impact Shared Regulatory Pathways Amongst Multimorbid Psychiatric Disorders and Cognitive Functioning.	Golovina E et al.	—	2020	→
High polygenic burden is associated with blood DNA methylation changes in individuals with suicidal behavior.	Cabrera-Mendoza B et al.	—	2020	→
Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors.	Ma Y et al.	—	2020	→
Identifying psychiatric disorder-associated gut microbiota using microbiota-related gene set enrichment analysis.	Cheng S et al.	—	2020	→
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Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update.	Gambardella J et al.	—	2020	→
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Lowering costs for large-scale screening in psychosis: a systematic review and meta-analysis of performance and value of information for speech-based psychiatric evaluation.	Argolo F et al.	—	2020	→
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Mapping associations between polygenic risks for childhood neuropsychiatric disorders, symptoms of attention deficit hyperactivity disorder, cognition, and the brain.	Sudre G et al.	—	2020	→
Maternal antenatal depression and child mental health: Moderation by genomic risk for attention-deficit/hyperactivity disorder.	Chen LM et al.	—	2020	→
Mental health dished up-the use of iPSC models in neuropsychiatric research.	McNeill RV et al.	—	2020	→
Meta-analysis of auditory P50 sensory gating in schizophrenia and bipolar disorder.	Atagun MI et al.	—	2020	→
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders.	Steen NE et al.	—	2020	→
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Minimal phenotyping yields genome-wide association signals of low specificity for major depression.	Cai N et al.	—	2020	→
Molecular linkage between post-traumatic stress disorder and cognitive impairment: a targeted proteomics study of World Trade Center responders.	Kuan PF et al.	—	2020	→
Morphometry and gyrification in bipolar disorder and schizophrenia: A comparative MRI study.	Madeira N et al.	—	2020	→
MR-LDP: a two-sample Mendelian randomization for GWAS summary statistics accounting for linkage disequilibrium and horizontal pleiotropy.	Cheng Q et al.	—	2020	→
Neurobiological commonalities and distinctions among 3 major psychiatric disorders: a graph theoretical analysis of the structural connectome	Wang S et al.	—	2020	→
Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings.	Scaini G et al.	—	2020	→
Neurobiology of maternal mental illness.	Maguire J et al.	—	2020	→
Neurological Disorders and Risk of Arrhythmia.	Bernardi J et al.	—	2020	→
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.	Khan TA et al.	—	2020	→
Neuronal α<sub>2</sub>δ proteins and brain disorders.	Ablinger C et al.	—	2020	→
One Single Nucleotide Polymorphism of the <i>TRPM2</i> Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population.	Mahmuda NA et al.	—	2020	→
On the diagnostic and neurobiological origins of bipolar disorder.	Charney AW et al.	—	2020	→
Ontogeny of inter-alpha inhibitor protein (IAIP) expression in human brain.	Kim B et al.	—	2020	→
Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity.	Yoshihara Y et al.	—	2020	→
Oxidative stress, metabolic and mitochondrial abnormalities associated with autism spectrum disorder.	Thorsen M	—	2020	→
Pilot study to establish a prospective neonatal cohort: Study of Preterm Infants and Neurodevelopmental Genes (SPRING).	Wong HS et al.	—	2020	→
Polygenetic Risk Scores for Major Psychiatric Disorders Among Schizophrenia Patients, Their First-Degree Relatives, and Healthy Participants.	Ohi K et al.	—	2020	→
Polygenic Risk Scores for Developmental Disorders, Neuromotor Functioning During Infancy, and Autistic Traits in Childhood.	Serdarevic F et al.	—	2020	→
Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits.	Gleason KJ et al.	—	2020	→
Psychiatric co-morbidities and factors associated with psychogenic non-epileptic seizures: a case-control study.	Gupta R et al.	—	2020	→
Rare variants and biological pathways identified in treatment-refractory depression.	McClain LL et al.	—	2020	→
Recent Advances in Understanding the Genetic Architecture of Autism.	Dias CM et al.	—	2020	→
Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.	Waszczuk MA et al.	—	2020	→
Replicated risk <i>CACNA1C</i> variants for major psychiatric disorders may serve as potential therapeutic targets for the shared depressive endophenotype.	Guo X et al.	—	2020	→
Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis.	Andersson A et al.	—	2020	→
Retinal function anomalies in young offspring at genetic risk of schizophrenia and mood disorder: The meaning for the illness pathophysiology.	Gagné AM et al.	—	2020	→
Schizophrenia research in the era of Team Science and big data.	Senthil G et al.	—	2020	→
Sensitivity and specificity of information criteria.	Dziak JJ et al.	—	2020	→
Sex-dependent effects of Cacna1c haploinsufficiency on behavioral inhibition evoked by conspecific alarm signals in rats.	Wöhr M et al.	—	2020	→
Sex-dependent effects of Cacna1c haploinsufficiency on juvenile social play behavior and pro-social 50-kHz ultrasonic communication in rats.	Kisko TM et al.	—	2020	→
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Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide.	Ruderfer DM et al.	—	2020	→
Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus.	Bakulski KM et al.	—	2020	→
Social withdrawal: An initially adaptive behavior that becomes maladaptive when expressed excessively.	Ike KGO et al.	—	2020	→
Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders.	Hammerschlag AR et al.	—	2020	→
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The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing.	Bogari NM et al.	—	2020	→
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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.	Coleman JRI et al.	—	2020	→
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The social neuroscience of psychosis: From neurobiology to neurotherapeutics.	Mehta UM	—	2020	→
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder.	Kathuria A et al.	—	2020	→
Transcriptomic abnormalities in peripheral blood in bipolar disorder, and discrimination of the major psychoses.	Hess JL et al.	—	2020	→
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia.	Kathuria A et al.	—	2020	→
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Transdiagnostic Prediction of Affective, Cognitive, and Social Function Through Brain Reward Anticipation in Schizophrenia, Bipolar Disorder, Major Depression, and Autism Spectrum Diagnoses.	Schwarz K et al.	—	2020	→
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Two Thalamic Regions Screened Using Laser Capture Microdissection with Whole Human Genome Microarray in Schizophrenia Postmortem Samples.	Bakshi K et al.	—	2020	→
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Using Two-Step Cluster Analysis and Latent Class Cluster Analysis to Classify the Cognitive Heterogeneity of Cross-Diagnostic Psychiatric Inpatients.	Benassi M et al.	—	2020	→
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A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data.	Wang Q et al.	—	2019	→
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A critical review of zebrafish schizophrenia models: Time for validation?	Gawel K et al.	—	2019	→
A Cross-Species Systems Genetics Analysis Links APBB1IP as a Candidate for Schizophrenia and Prepulse Inhibition.	Ashbrook DG et al.	—	2019	→
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A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression.	Shimanoe C et al.	—	2019	→
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.	Demontis D et al.	—	2019	→
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Examining overlap and homogeneity in ASD, ADHD, and OCD: a data-driven, diagnosis-agnostic approach.	Kushki A et al.	—	2019	→
Examining sex differences in pleiotropic effects for depression and smoking using polygenic and gene-region aggregation techniques.	Schmitz LL et al.	—	2019	→
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease.	Creese B et al.	—	2019	→
Family-based association study of ZNF804A polymorphisms and autism in a Han Chinese population.	Wang Z et al.	—	2019	→
Family History of Mental and Neurological Disorders and Risk of Autism.	Xie S et al.	—	2019	→
First episode psychosis and comorbid ADHD, autism and intellectual disability.	Strålin P et al.	—	2019	→
Gene-based analysis of ADHD using PASCAL: a biological insight into the novel associated genes.	Alonso-Gonzalez A et al.	—	2019	→
Gene-Environment Interactions in Psychiatry: Recent Evidence and Clinical Implications.	Musci RJ et al.	—	2019	→
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.	Huckins LM et al.	—	2019	→
Genes, biomarkers, and clinical features associated with the course of bipolar disorder.	Smedler E et al.	—	2019	→
Genes with High Network Connectivity Are Enriched for Disease Heritability.	Kim SS et al.	—	2019	→
Genetic Associations between Voltage-Gated Calcium Channels and Psychiatric Disorders.	Andrade A et al.	—	2019	→
Genetic Causes and Modifiers of Autism Spectrum Disorder.	Rylaarsdam L et al.	—	2019	→
Genetic risk for bipolar disorder and psychopathology from childhood to early adulthood.	Mistry S et al.	—	2019	→
Genetic risk for schizophrenia is associated with substance use in emerging adulthood: an event-level polygenic prediction model.	Mallard TT et al.	—	2019	→
Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders.	Bauer AE et al.	—	2019	→
Genetics and genetic counseling in psychiatry: Results from an opinion survey of professionals and users.	Martorell L et al.	—	2019	→
Genetics of Anxiety Disorders.	Meier SM et al.	—	2019	→
Genetics of attention deficit hyperactivity disorder.	Faraone SV et al.	—	2019	→
Genetics of Eating Disorders: What the Clinician Needs to Know.	Bulik CM et al.	—	2019	→
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.	Jones SE et al.	—	2019	→
Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study.	Meier SM et al.	—	2019	→
Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species.	Sykes L et al.	—	2019	→
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.	Jones SE et al.	—	2019	→
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.	Ikeda M et al.	—	2019	→
Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population.	Koshimizu H et al.	—	2019	→
Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans.	Gelernter J et al.	—	2019	→
Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples.	Fabbri C et al.	—	2019	→
Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders	Cross-Disorder Group of the Psychiatric Genomics Consortium et al.	—	2019	—
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.	Howard DM et al.	—	2019	→
Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women.	Montalvo-Ortiz JL et al.	—	2019	→
Genome-Wide Variants Shared Between Smoking Quantity and Schizophrenia on 15q25 Are Associated With CHRNA5 Expression in the Brain.	Ohi K et al.	—	2019	→
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.	Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu et al.	—	2019	→
GWAS of Behavioral Traits.	Mehta D et al.	—	2019	→
HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases.	Jordan DM et al.	—	2019	→
Human brain arousal in the resting state: a genome-wide association study.	Jawinski P et al.	—	2019	→
<i>CACNB2</i> Is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.	Vuori N et al.	—	2019	→
Identification of Common Thalamocortical Dysconnectivity in Four Major Psychiatric Disorders.	Tu PC et al.	—	2019	→
Identification of genes related to mental disorders by text mining.	Wu Y et al.	—	2019	→
Imaging Genetics Towards a Refined Diagnosis of Schizophrenia.	Jiang W et al.	—	2019	→
Impact of major depression on cardiovascular outcomes for individuals with hypertension: prospective survival analysis in UK Biobank.	Graham N et al.	—	2019	→
Increased Ca<sup>2+</sup> signaling in <i>NRXN1α</i><sup><i>+/-</i></sup> neurons derived from ASD induced pluripotent stem cells.	Avazzadeh S et al.	—	2019	→
Increased risk of ADHD in families with ASD.	Septier M et al.	—	2019	→
Indicators of mental disorders in UK Biobank-A comparison of approaches.	Davis KAS et al.	—	2019	→
Influence of genetic factors on long-term treatment related neurocognitive complications, and on anxiety and depression in survivors of childhood acute lymphoblastic leukemia: The Petale study.	Petrykey K et al.	—	2019	→
In search of disorders: internalizing symptom networks in a large clinical sample.	McElroy E et al.	—	2019	→
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.	Czamara D et al.	—	2019	→
Integrating predicted transcriptome from multiple tissues improves association detection.	Barbeira AN et al.	—	2019	→
Integrating proteomic, sociodemographic and clinical data to predict future depression diagnosis in subthreshold symptomatic individuals.	Han SYS et al.	—	2019	→
Interaction of the Psychiatric Risk Gene <i>Cacna1c</i> With Post-weaning Social Isolation or Environmental Enrichment Does Not Affect Brain Mitochondrial Bioenergetics in Rats.	Michels S et al.	—	2019	→
Inter-α-inhibitor deficiency in the mouse is associated with alterations in anxiety-like behavior, exploration and social approach.	Goulding DR et al.	—	2019	→
Investigating associations between genetic risk for bipolar disorder and cognitive functioning in childhood.	Mistry S et al.	—	2019	→
Is aberrant affective cognition an endophenotype for affective disorders? - A monozygotic twin study.	Meluken I et al.	—	2019	→
Joint analysis of individual-level and summary-level GWAS data by leveraging pleiotropy.	Dai M et al.	—	2019	→
Large-Scale Population-Based Assessment of Psychiatric Comorbidities in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder.	Turner TN	—	2019	→
Longitudinal trajectory of early functional recovery in patients with first episode psychosis.	Hall MH et al.	—	2019	→
Maternal antenatal daytime sleepiness and child neuropsychiatric and neurocognitive development.	Lahti-Pulkkinen M et al.	—	2019	→
MeCP2 Dysfunction in Rett Syndrome and Neuropsychiatric Disorders.	Chin EWM et al.	—	2019	→
Microduplications at the 15q11.2 BP1-BP2 locus are enriched in patients with anorexia nervosa.	Chang X et al.	—	2019	→
Missing a beat: assessment of circadian rhythm abnormalities in bipolar disorder in the genomic era.	McCarthy MJ	—	2019	→
Mitochondria, Metabolism, and Redox Mechanisms in Psychiatric Disorders.	Kim Y et al.	—	2019	→
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients.	Ma L et al.	—	2019	→
Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA.	Jia X et al.	—	2019	→
National Institute on Drug Abuse genomics consortium white paper: Coordinating efforts between human and animal addiction studies.	Cates HM et al.	—	2019	→
Neonatal amygdalae and hippocampi are influenced by genotype and prenatal environment, and reflected in the neonatal DNA methylome.	Ong ML et al.	—	2019	→
Neurobiology of the major psychoses: a translational perspective on brain structure and function-the FOR2107 consortium.	Kircher T et al.	—	2019	→
Neuroimaging Markers of Risk, Disease Expression, and Resilience to Bipolar Disorder.	Frangou S	—	2019	→
Neuroimaging Studies in Patients With Mental Disorder and Co-occurring Substance Use Disorder: Summary of Findings.	Stoychev KR	—	2019	→
Neuronal Antibodies and Associated Syndromes.	Arneth BM	—	2019	→
Novel Gene-Based Analysis of ASD GWAS: Insight Into the Biological Role of Associated Genes.	Alonso-Gonzalez A et al.	—	2019	→
NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis.	Alliey-Rodriguez N et al.	—	2019	→
Objective and biological markers in bipolar spectrum presentations.	Chakrabarty T et al.	—	2019	→
On the Specificity of Continuous Cognitive Decline in Schizophrenia.	Kahn RS	—	2019	→
Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.	Zheutlin AB et al.	—	2019	→
Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions.	Thyme SB et al.	—	2019	→
Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development.	Cullen H et al.	—	2019	→
Polygenic risk for psychiatric disorder and singleness in patients with severe mental illness and controls.	Hjorthøj C et al.	—	2019	→
Polygenic risk for psychiatric disorders correlates with executive function in typical development.	Schork AJ et al.	—	2019	→
Polygenic risk for schizophrenia and associated brain structural changes: A systematic review.	van der Merwe C et al.	—	2019	→
Polygenic risk scoring and prediction of mental health outcomes.	Anderson JS et al.	—	2019	→
Prediction of Response to Drug Therapy in Psychiatric Disorders.	Stern S et al.	—	2019	→
Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage.	Lee C et al.	—	2019	→
Psychiatrists are experts when it comes to missing boats. Will prevention be the next one?	Arango C	—	2019	→
Putative contributions of the sex chromosome proteins SOX3 and SRY to neurodevelopmental disorders.	Tahira AC et al.	—	2019	→
Reasoning bias, working memory performance and a transdiagnostic phenotype of affective disturbances and psychotic experiences in the general population.	Reininghaus U et al.	—	2019	→
Recent Advances in the Genetics of Fractures in Osteoporosis.	Koromani F et al.	—	2019	→
Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research.	Szczepek AJ et al.	—	2019	→
Rediscovering the value of families for psychiatric genetics research.	Glahn DC et al.	—	2019	→
Relationships between substance abuse/dependence and psychiatric disorders based on polygenic scores.	Gurriarán X et al.	—	2019	→
Remitted affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota.	Vinberg M et al.	—	2019	→
Replication of previous GWAS hits suggests the association between rs4307059 near MSNP1AS and autism in a Chinese Han population.	Wang Z et al.	—	2019	→
Research Domain Criteria: Strengths, Weaknesses, and Potential Alternatives for Future Psychiatric Research.	Ross CA et al.	—	2019	→
Risk and coaggregation of major psychiatric disorders among first-degree relatives of patients with bipolar disorder: a nationwide population-based study.	Chen MH et al.	—	2019	→
Risk of non-affective psychotic disorder or bipolar disorder in autism spectrum disorder: a longitudinal register-based study in the Netherlands.	Schalbroeck R et al.	—	2019	→
Schizophrenia liability shares common molecular genetic risk factors with sleep duration and nightmares in childhood.	Reed ZE et al.	—	2019	→
Shared and Distinct Functional Architectures of Brain Networks Across Psychiatric Disorders.	Xia M et al.	—	2019	→
Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness.	Jiang X et al.	—	2019	→
Spontaneous low-frequency fluctuations in the neural system for emotional perception in major psychiatric disorders: amplitude similarities and differences across frequency bands	Chang M et al.	—	2019	→
Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases.	Asimit JL et al.	—	2019	→
Stress during critical periods of development and risk for schizophrenia.	Gomes FV et al.	—	2019	→
Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes.	Zimmermann CA et al.	—	2019	→
Symptom-based patient stratification in mental illness using clinical notes.	Liu Q et al.	—	2019	→
Target Genes of Autism Risk Loci in Brain Frontal Cortex.	Sun Y et al.	—	2019	→
The bidirectional causal relationships of insomnia with five major psychiatric disorders: A Mendelian randomization study.	Gao X et al.	—	2019	→
The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study.	D'Ambrosio E et al.	—	2019	→
The ethics of global psychiatric genomics: Multilayered challenges to integrating genomics in global mental health and disability-A position paper of the Oxford Global Initiative in Neuropsychiatric GenEthics (NeuroGenE).	Kong C et al.	—	2019	→
The Genetics of Treatment-Resistant Depression: A Critical Review and Future Perspectives.	Fabbri C et al.	—	2019	→
The Heterogeneity Problem: Approaches to Identify Psychiatric Subtypes.	Feczko E et al.	—	2019	→
The <i>ANKS1B</i> gene and its associated phenotypes: focus on CNS drug response.	Younis RM et al.	—	2019	→
The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.	Duarte RRR et al.	—	2019	→
The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia.	Rammos A et al.	—	2019	→
The schizophrenia and bipolar twin study in Sweden (STAR).	Johansson V et al.	—	2019	→
The Translational Potential of Neuroimaging Genomic Analyses To Diagnosis And Treatment In The Mental Disorders.	Chen J et al.	—	2019	→
Toward a Better Understanding of Neuronal Migration Deficits in Autism Spectrum Disorders.	Pan YH et al.	—	2019	→
Translational bioinformatics in mental health: open access data sources and computational biomarker discovery.	Tenenbaum JD et al.	—	2019	→
Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus.	Yu Z et al.	—	2019	→
Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort.	O'Connell KS et al.	—	2019	→
Whole Exome Sequencing Identifies a Novel Predisposing Gene, MAPKAP1, for Familial Mixed Mood Disorder.	Yang C et al.	—	2019	→
A Critical Neurodevelopmental Role for L-Type Voltage-Gated Calcium Channels in Neurite Extension and Radial Migration.	Kamijo S et al.	—	2018	→
Additional common variants associated with type 2 diabetes and coronary artery disease detected using a pleiotropic cFDR method.	Zhang Q et al.	—	2018	→
Advances in our understanding of the genetics of childhood neurodevelopmental disorders.	Doherty J et al.	—	2018	→
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.	Zhu Z et al.	—	2018	→
A large-scale integrative analysis of GWAS and common meQTLs across whole life course identifies genes, pathways and tissue/cell types for three major psychiatric disorders.	Zhao Y et al.	—	2018	→
A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia.	Li W et al.	—	2018	→
A polygenic p factor for major psychiatric disorders.	Selzam S et al.	—	2018	→
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.	de Jong S et al.	—	2018	→
A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity.	Yamashita M et al.	—	2018	→
A retrospective analysis of the development of seizure frequency in patients with seizures during a period of military conflict.	Appel S et al.	—	2018	→
Assessment of Cognition and Personality as Potential Endophenotypes in the Western Australian Family Study of Schizophrenia.	McCarthy NS et al.	—	2018	→
Association Between Autism Spectrum Disorders With or Without Intellectual Disability and Depression in Young Adulthood.	Rai D et al.	—	2018	→
Association between family history of mental disorders and outcome in psychotic disorders.	Käkelä J et al.	—	2018	→
Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder.	Markota M et al.	—	2018	→
Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition.	Ranlund S et al.	—	2018	→
A systematic review of genome-wide research on psychotic experiences and negative symptom traits: new revelations and implications for psychiatry.	Ronald A et al.	—	2018	→
Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood.	Meier SM et al.	—	2018	→
Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology.	Georgieff MK et al.	—	2018	→
Autism throughout genetics: Perusal of the implication of ion channels.	Daghsni M et al.	—	2018	→
Biomarkers for Depression: Recent Insights, Current Challenges and Future Prospects.	Strawbridge R et al.	—	2018	→
Ca2+ Channels in Anterior Pituitary Somatotrophs: A Therapeutic Perspective.	Nussinovitch I	—	2018	→
CACNA1C: Association With Psychiatric Disorders, Behavior, and Neurogenesis.	Moon AL et al.	—	2018	→
Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia.	Song JHT et al.	—	2018	→
Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells.	Hoffmann A et al.	—	2018	→
Clozapine Pharmacogenetic Studies in Schizophrenia: Efficacy and Agranulocytosis.	Numata S et al.	—	2018	→
Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network.	Jia P et al.	—	2018	→
Cross-genetic determination of maternal and neonatal immune mediators during pregnancy.	Traglia M et al.	—	2018	→
Dimensional thinking in psychiatry in the era of the Research Domain Criteria (RDoC).	Kelly JR et al.	—	2018	→
Discoveries on the Genetics of ADHD in the 21st Century: New Findings and Their Implications.	Thapar A	—	2018	→
Downregulation of the psychiatric susceptibility gene <i>Cacna1c</i> promotes mitochondrial resilience to oxidative stress in neuronal cells.	Michels S et al.	—	2018	→
Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia.	Konopaske GT et al.	—	2018	→
Expanding the clinical relevance of the 5'-nucleotidase cN-II/NT5C2.	Jordheim LP	—	2018	→
Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.	Guo W et al.	—	2018	→
Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children.	Taylor AE et al.	—	2018	→
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.	Barbeira AN et al.	—	2018	→
Finding associated variants in genome-wide association studies on multiple traits.	Gai L et al.	—	2018	→
Fractional anisotropy of the uncinate fasciculus and cingulum in bipolar disorder type I, type II, unaffected siblings and healthy controls.	Foley SF et al.	—	2018	→
FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications.	Backenroth D et al.	—	2018	→
Further Evidence of an Association between <i>NCAN</i> rs1064395 and Bipolar Disorder.	Wang L et al.	—	2018	→
Gene × Environment Interaction in Developmental Disorders: Where Do We Stand and What's Next?	Esposito G et al.	—	2018	→
Gene-level associations in suicide attempter families show overrepresentation of synaptic genes and genes differentially expressed in brain development.	Sokolowski M et al.	—	2018	→
Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).	Ren H et al.	—	2018	→
Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.	Tylee DS et al.	—	2018	→
Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.	Bansal V et al.	—	2018	→
Genome-wide association study reveals novel genetic locus associated with intra-individual variability in response time.	Pinar A et al.	—	2018	→
Genomic variants in an inbred mouse model predict mania-like behaviors.	Saul MC et al.	—	2018	→
Genotype-phenotype correlations in Darier disease: A focus on the neuropsychiatric phenotype.	Gordon-Smith K et al.	—	2018	→
Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.	Qi G et al.	—	2018	→
Heritability of obsessive-compulsive trait dimensions in youth from the general population.	Burton CL et al.	—	2018	→
Higher Polygenetic Predisposition for Asthma in Cow's Milk Allergic Children.	Jansen PR et al.	—	2018	→
HLA-class II haplotypes and Autism Spectrum Disorders.	Bennabi M et al.	—	2018	→
Hypomethylation of LINE-1 elements in schizophrenia and bipolar disorder.	Li S et al.	—	2018	→
<i>Cacna1c</i> haploinsufficiency leads to pro-social 50-kHz ultrasonic communication deficits in rats.	Kisko TM et al.	—	2018	→
Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.	Bhalala OG et al.	—	2018	→
Increased Risk for Neurodevelopmental Disorders in Children With Orofacial Clefts.	Tillman KK et al.	—	2018	→
Individual, programmatic and systemic indicators of the quality of mental health care using a large health administrative database: an avenue for preventing suicide mortality.	Thibodeau L et al.	—	2018	→
Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data.	Burgess S et al.	—	2018	→
International Union of Basic and Clinical Pharmacology CIV: The Neurobiology of Treatment-resistant Depression: From Antidepressant Classifications to Novel Pharmacological Targets.	Caraci F et al.	—	2018	→
Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways.	Nguyen RL et al.	—	2018	→
Investigating the genetic architecture of general and specific psychopathology in adolescence.	Jones HJ et al.	—	2018	→
ITIH3 and ITIH4 polymorphisms and depressive symptoms during pregnancy in Japan: the Kyushu Okinawa Maternal and Child Health Study.	Miyake Y et al.	—	2018	→
<i>VRK2</i>, a Candidate Gene for Psychiatric and Neurological Disorders.	Li M et al.	—	2018	→
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals.	Zak N et al.	—	2018	→
LSMM: a statistical approach to integrating functional annotations with genome-wide association studies.	Ming J et al.	—	2018	→
Maternal depression and antidepressant use during pregnancy and the risk of autism spectrum disorder in offspring.	Hagberg KW et al.	—	2018	→
microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease.	Thomas KT et al.	—	2018	→
Mini-review: Update on the genetics of schizophrenia.	Coelewij L et al.	—	2018	→
Molecular genetic overlap between migraine and major depressive disorder.	Yang Y et al.	—	2018	→
Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample.	Calabrò M et al.	—	2018	→
Opportunities for an enhanced integration of neuroscience and genomics.	Moore AA et al.	—	2018	→
Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a.	Cheng Y et al.	—	2018	→
Pleiotropic mapping and annotation selection in genome-wide association studies with penalized Gaussian mixture models.	Zeng P et al.	—	2018	→
PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies.	Hecker J et al.	—	2018	→
Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.	Lin YF et al.	—	2018	→
Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences.	Bogdan R et al.	—	2018	→
Polygenic Risk Scores: What Are They Good For?	Zheutlin AB et al.	—	2018	→
Positive and balancing selection on <i>SLC18A1</i> gene associated with psychiatric disorders and human-unique personality traits.	Sato DX et al.	—	2018	→
Pre- and Perinatal Risk Factors for Serious Mental Disorders: Ethical Considerations in Prevention and Prediction Efforts.	Ellman LM et al.	—	2018	→
Precision pharmacotherapy: psychiatry's future direction in preventing, diagnosing, and treating mental disorders.	Menke A	—	2018	→
Prediction of response to drug therapy in psychiatric disorders.	Stern S et al.	—	2018	→
Presynaptic disorders: a clinical and pathophysiological approach focused on the synaptic vesicle.	Cortès-Saladelafont E et al.	—	2018	→
Promoter Polymorphisms of TNF-α Gene as a Risk Factor for Schizophrenia.	Suchanek-Raif R et al.	—	2018	→
Prosody abilities in a large sample of affective and non-affective first episode psychosis patients.	Caletti E et al.	—	2018	→
PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.	Chen LM et al.	—	2018	→
Psychiatric risk gene Cacna1c determines mitochondrial resilience against oxidative stress in neurons.	Michels S et al.	—	2018	→
Psychiatry and developmental psychopathology: Unifying themes and future directions.	Beauchaine TP et al.	—	2018	→
Recent developments in the genetics of attention-deficit hyperactivity disorder.	Grimm O et al.	—	2018	→
Recent Findings in the Genetics of Blood Pressure: How to Apply in Practice or Is a Moonshot Required?	Padmanabhan S et al.	—	2018	→
Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder.	Nishino J et al.	—	2018	→
Should Clinicians Split or Lump Psychiatric Symptoms? The Structure of Psychopathology in Two Large Pediatric Clinical Samples from England and Norway.	Fernández de la Cruz L et al.	—	2018	→
Stable <i>STIM1</i> Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation.	Gopurappilly R et al.	—	2018	→
Stem Cells, Genome Editing, and the Path to Translational Medicine.	Soldner F et al.	—	2018	→
Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease.	Brown J et al.	—	2018	→
Sub-circuit alterations in dorsal hippocampus structure and function after global neurodevelopmental insult.	O'Reilly KC et al.	—	2018	→
Sustained Attention and Interference Control Among 7-Year-Old Children With a Familial High Risk of Schizophrenia or Bipolar Disorder-A Nationwide Observational Cohort Study.	Burton BK et al.	—	2018	→
The "concept-reality mismatch" in the globalization era as a psychosocial stressor contributing to the occurrence of mental disorders.	Bou Khalil R	—	2018	→
The Emerging Immunogenetic Architecture of Schizophrenia.	Pouget JG	—	2018	→
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.	Willsey AJ et al.	—	2018	→
The role of genetics and genomics in clinical psychiatry.	Hoehe MR et al.	—	2018	→
Tracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells.	Ahmad R et al.	—	2018	→
Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders.	Calafato MS et al.	—	2018	→
Voltage-gated calcium channel activity and complex related genes and schizophrenia: A systematic investigation based on Han Chinese population.	Zhang T et al.	—	2018	→
Whole-genome sequencing in a family with twin boys with autism and intellectual disability suggests multimodal polygenic risk.	McKenna B et al.	—	2018	→