biologically related genes (appendix pp 14–16). We did eQTL enrichment analysis20 to assess whether SNPs associated with five psychiatric disorders were enriched for regulatory SNPs in post-mortem brain tissue samples compared with those with no association.21,22 To assess the specificity of this finding, we also examined eQTL datasets from three non-brain-tissue types: liver,23 skin,24 and lymphoblastoid cell lines25 (appendix pp 17–21).
