Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
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- Authors
- Liu, Y; Blackwood, D H; Caesar, S; de Geus, E J C; Farmer, A; Ferreira, M A R; Ferrier, I N; Fraser, C; Gordon-Smith, K; Green, E K; Grozeva, D; Gurling, H M; Hamshere, M L; Heutink, P; Holmans, P A; Hoogendijk, W J; Hottenga, J J; Jones, L; Jones, I R; Kirov, G; Lin, D; McGuffin, P; Moskvina, V; Nolen, W A; Perlis, R H; Posthuma, D; Scolnick, E M; Smit, A B; Smit, J H; Smoller, J W; St Clair, D; van Dyck, R; Verhage, M; Willemsen, G; Young, A H; Zandbelt, T; Boomsma, D I; Craddock, N; O'Donovan, M C; Owen, M J; Penninx, B W J H; Purcell, S; Sklar, P; Sullivan, P F; Wellcome Trust Case-Control Consortium
- Year
- 2011
- Journal
- Molecular psychiatry
- PMID
- 20351715
- DOI
- 10.1038/mp.2009.107
- PMCID
- PMC3883627
Results of GWAS meta-analysis for BIP and MDD. A) Quantile-quantile plot of the meta-analytic results (observed × expected p-values on −log10 scale). B) Manhattan plot (−log10 of fixed-effects p-value × genomic position). C) The CACNA1C region (red diamonds indicate SNPs genotyped in both studies, gold SNPs genotyped in one study and imputed in the other, and gray SNPs imputed in both studies).
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