Practical aspects of imputation-driven meta-analysis of genome-wide association studies.
paper
Cited
Public
Unavailable
- Authors
- de Bakker, Paul I W; Ferreira, Manuel A R; Jia, Xiaoming; Neale, Benjamin M; Raychaudhuri, Soumya; Voight, Benjamin F
- Year
- 2008
- Journal
- Human molecular genetics
- PMID
- 18852200
- DOI
- 10.1093/hmg/ddn288
- PMCID
- PMC2782358
Motivated by the overwhelming success of genome-wide association studies, droves of researchers are working vigorously to exchange and to combine genetic data to expediently discover genetic risk factors for common human traits. The primary tools that fuel these new efforts are imputation, allowing researchers who have collected data on a diversity of genotype platforms to share data in a uniformly exchangeable format, and meta-analysis for pooling statistical support for a genotype-phenotype association. As many groups are forming collaborations to engage in these efforts, this review collects a series of guidelines, practical detail and learned experiences from a variety of individuals who have contributed to the subject.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
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| Genetic risk factors modulate the association between physical activity and colorectal cancer. | Peoples AR et al. | β | 2026 | β |
| A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism. | Oh K et al. | β | 2025 | β |
| A meta-analysis of genome-wide association studies revealed significant QTL and candidate genes for loin muscle area in three breeding pigs. | Zhenyu W et al. | β | 2025 | β |
| A meta-analysis of genome-wide association studies to identify candidate genes associated with feed efficiency traits in pigs. | Silva MRGD et al. | β | 2025 | β |
| Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes. | Sierant MC et al. | β | 2025 | β |
| Integrative Gene-Centric Analysis Reveals Cellular Pathways Associated with Heritable Breast Cancer Predisposition. | Zucker R et al. | β | 2025 | β |
| Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies. | Wang S et al. | β | 2024 | β |
| Advancing human genotyping: The Infinium HTS iSelect Custom microarray panel (Rita) development study. | Pedroza Matute S et al. | β | 2024 | β |
| Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer. | Papadimitriou N et al. | β | 2024 | β |
| <i>TMEM132C</i> rs7296262 Single-Nucleotide Polymorphism Is Significantly Associated with Nausea Induced by Opioids Administered for Cancer Pain and Postoperative Pain. | Kang Y et al. | β | 2024 | β |
| SNP Genotype Imputation in Forensics-A Performance Study. | Tillmar A et al. | β | 2024 | β |
| Unveiling the predominance of Saccharum spontaneum alleles for resistance to orange rust in sugarcane using genome-wide association. | Dijoux J et al. | β | 2024 | β |
| A Study on South Korean College Students' Perceptions of Gratitude. | Lee N et al. | β | 2023 | β |
| Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. | Wang A et al. | β | 2023 | β |
| Evaluation of Genetic and Nongenetic Risk Factors for Degenerative Cervical Myelopathy. | Shlykov MA et al. | β | 2023 | β |
| Genetic Risk of Primary Aldosteronism and Its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies. | Naito T et al. | β | 2023 | β |
| Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank. | Sugawara Y et al. | β | 2023 | β |
| Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response. | Pagadala M et al. | β | 2023 | β |
| GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture. | International League Against Epilepsy Consortium on Complex Epilepsies | β | 2023 | β |
| Identification of Novel Genetic Markers for the Risk of Spinal Pathologies: A Genome-Wide Association Study of 2 Biobanks. | Bovonratwet P et al. | β | 2023 | β |
| Nuclear genetic control of mtDNA copy number and heteroplasmy in humans. | Gupta R et al. | β | 2023 | β |
| Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses. | Dimou N et al. | β | 2023 | β |
| Application of hyperglycemia/diabetes-derived polygenic risk scores on the risk of poor outcomes after an ischemic stroke. | Chen YL et al. | β | 2022 | β |
| Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms. | Schmidt AW et al. | β | 2022 | β |
| Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology. | Ahmed M et al. | β | 2022 | β |
| Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress. | Katrinli S et al. | β | 2022 | β |
| Genetics of Type 2 Diabetes: Past, Present, and Future. | Laakso M et al. | β | 2022 | β |
| Genetic susceptibility to autoimmunity-Current status and challenges. | Huang M et al. | β | 2022 | β |
| Genome-Wide Association Study Identifies Candidate Loci Associated with Opioid Analgesic Requirements in the Treatment of Cancer Pain. | Nishizawa D et al. | β | 2022 | β |
| Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health. | Wang G et al. | β | 2022 | β |
| MagicalRsq: Machine-learning-based genotype imputation quality calibration. | Sun Q et al. | β | 2022 | β |
| Mendelian Randomization and GWAS Meta Analysis Revealed the Risk-Increasing Effect of Schizophrenia on Cancers. | Yuan K et al. | β | 2022 | β |
| The BS variant of C4 protects against age-related loss of white matter microstructural integrity. | Traylor M et al. | β | 2022 | β |
| The Candidate Chromosomal Regions Responsible for Milk Yield of Cow: A GWAS Meta-Analysis. | Taherkhani L et al. | β | 2022 | β |
| A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. | Wightman DP et al. | β | 2021 | β |
| A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. | Choquet H et al. | β | 2021 | β |
| A meta-analysis of genome-wide association studies for average daily gain and lean meat percentage in two Duroc pig populations. | Zhou S et al. | β | 2021 | β |
| False positive findings during genome-wide association studies with imputation: influence of allele frequency and imputation accuracy. | Zhang Z et al. | β | 2021 | β |
| Genetically determined intelligence and coronary artery disease risk. | Li L et al. | β | 2021 | β |
| Identification of a Novel Genetic Marker for Risk of Degenerative Rotator Cuff Disease Surgery in the UK Biobank. | Yanik EL et al. | β | 2021 | β |
| Investigative genetic genealogy: Current methods, knowledge and practice. | Kling D et al. | β | 2021 | β |
| Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. | Nabais MF et al. | β | 2021 | β |
| Meta-Analysis of Joint Test of SNP and SNP-Environment Interaction with Heterogeneity. | Jin Q et al. | β | 2021 | β |
| Rostral middle frontal gyrus thickness mediates the relationship between genetic risk and neuroticism trait. | Song L et al. | β | 2021 | β |
| The genomics of heart failure: design and rationale of the HERMES consortium. | Lumbers RT et al. | β | 2021 | β |
| Trans-Ethnic Fine-Mapping of the Major Histocompatibility Complex Region Linked to Parkinson's Disease. | Naito T et al. | β | 2021 | β |
| Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. | Somineni HK et al. | β | 2021 | β |
| Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children. | Mateos MK et al. | β | 2020 | β |
| Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy. | Li M et al. | β | 2020 | β |
| Nordic OCD & Related Disorders Consortium: Rationale, design, and methods. | Mataix-Cols D et al. | β | 2020 | β |
| A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. | Chernus JM et al. | β | 2019 | β |
| A comparative analysis of cell-type adjustment methods for epigenome-wide association studies based on simulated and real data sets. | BrΓ€gelmann J et al. | β | 2019 | β |
| Association mapping in plants in the post-GWAS genomics era. | Gupta PK et al. | β | 2019 | β |
| Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. | Coleman JRI et al. | β | 2019 | β |
| Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. | Agha G et al. | β | 2019 | β |
| Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls. | Lutz SM et al. | β | 2019 | β |
| FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: The PACMAN study. | Karimi L et al. | β | 2019 | β |
| Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. | van Setten J et al. | β | 2019 | β |
| Genome-wide association studies of structural birth defects: A review and commentary. | Lupo PJ et al. | β | 2019 | β |
| Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease. | SΓ‘ez ME et al. | β | 2019 | β |
| Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. | Jansen IE et al. | β | 2019 | β |
| Genomic analyses in African populations identify novel risk loci for cleft palate. | Butali A et al. | β | 2019 | β |
| Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. | LindstrΓΆm S et al. | β | 2019 | β |
| Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population. | Low SK et al. | β | 2019 | β |
| Identifying markers for resistance to sugarcane orange rust (Puccinia kuehnii) via selective genotyping and capture sequencing | McCord P et al. | β | 2019 | β |
| Meta-analysis of genome-wide association studies provides insights into genetic control of tomato flavor. | Zhao J et al. | β | 2019 | β |
| Statistical methods for genome-wide association studies. | Wang MH et al. | β | 2019 | β |
| Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. | Onengut-Gumuscu S et al. | β | 2019 | β |
| A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. | Zhu Z et al. | β | 2018 | β |
| Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease. | Amininejad L et al. | β | 2018 | β |
| An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group. | Boedhoe PSW et al. | β | 2018 | β |
| Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. | Schumacher FR et al. | β | 2018 | β |
| Better ILP models for haplotype assembly. | Etemadi M et al. | β | 2018 | β |
| Causal associations between risk factors and common diseases inferred from GWAS summary data. | Zhu Z et al. | β | 2018 | β |
| Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese. | Okada Y et al. | β | 2018 | β |
| Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. | Bryois J et al. | β | 2018 | β |
| Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. | Yu H et al. | β | 2018 | β |
| Genetic associations with childhood brain growth, defined in two longitudinal cohorts. | Szekely E et al. | β | 2018 | β |
| Genome-wide association study identifies inversion in the <i>CTRB1-CTRB2</i> locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. | Rosendahl J et al. | β | 2018 | β |
| Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. | Vijayakrishnan J et al. | β | 2018 | β |
| Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. | Endo C et al. | β | 2018 | β |
| Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. | Khor SS et al. | β | 2018 | β |
| Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. | Li Y et al. | β | 2018 | β |
| Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. | International League Against Epilepsy Consortium on Complex Epilepsies | β | 2018 | β |
| Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. | Klein AP et al. | β | 2018 | β |
| Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference. | Lin Y et al. | β | 2018 | β |
| Mendelian randomisation study of the relationship between vitamin D and risk of glioma. | Takahashi H et al. | β | 2018 | β |
| Meta-Analysis of Common and Rare Variants. | Michailidou K | β | 2018 | β |
| PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. | van Setten J et al. | β | 2018 | β |
| Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD). | Holmans P et al. | β | 2018 | β |
| XPAT: a toolkit to conduct cross-platform association studies with heterogeneous sequencing datasets. | Yu Y et al. | β | 2018 | β |
| A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. | Vijayakrishnan J et al. | β | 2017 | β |
| A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis. | Ng M et al. | β | 2017 | β |
| A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. | Chang D et al. | β | 2017 | β |
| Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation. | Winkler TW et al. | β | 2017 | β |
| Circadian CLOCK gene polymorphisms in relation to sleep patterns and obesity in African Americans: findings from the Jackson heart study. | Riestra P et al. | β | 2017 | β |
| Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population. | Yu H et al. | β | 2017 | β |
| Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. | Hu Y et al. | β | 2017 | β |
| Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport. | Kunkle BW et al. | β | 2017 | β |
| Exome sequence genotype imputation in globally diverse hexaploid wheat accessions. | Shi F et al. | β | 2017 | β |
| Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders. | Holmans PA et al. | β | 2017 | β |
| Genetic variation at 16q24.2 is associated with small vessel stroke. | Traylor M et al. | β | 2017 | β |
| Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs. | Petros Z et al. | β | 2017 | β |
| Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. | Veenstra J et al. | β | 2017 | β |
| GWAR: robust analysis and meta-analysis of genome-wide association studies. | Dimou NL et al. | β | 2017 | β |
| Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects. | Lee CH et al. | β | 2017 | β |
| Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation. | Brynedal B et al. | β | 2017 | β |
| Linkage disequilibrium matches forensic genetic records to disjoint genomic marker sets. | Edge MD et al. | β | 2017 | β |
| Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. | Heilmann-Heimbach S et al. | β | 2017 | β |
| Meta-analysis of gene-environment interaction exploiting gene-environment independence across multiple case-control studies. | Estes JP et al. | β | 2017 | β |
| Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. | Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium | β | 2017 | β |
| Molecular Epidemiology of Heart Failure: Translational Challenges and Opportunities. | Smith JG | β | 2017 | β |
| A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. | Scarbrough PM et al. | β | 2016 | β |
| Adaptive gene- and pathway-trait association testing with GWAS summary statistics. | Kwak IY et al. | β | 2016 | β |
| A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping. | Han B et al. | β | 2016 | β |
| Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment. | Louwersheimer E et al. | β | 2016 | β |
| An Empirical Comparison of Joint and Stratified Frameworks for Studying G Γ E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group. | Sung YJ et al. | β | 2016 | β |
| Application of computational methods in genetic study of inflammatory bowel disease. | Li J et al. | β | 2016 | β |
| Ascertainment bias from imputation methods evaluation in wheat. | Brandariz SP et al. | β | 2016 | β |
| Common Genetic Variant in VIT Is Associated with Human Brain Asymmetry. | Tadayon SH et al. | β | 2016 | β |
| Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores. | Lee CH et al. | β | 2016 | β |
| Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set. | Kanai M et al. | β | 2016 | β |
| Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. | Hong J et al. | β | 2016 | β |
| Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations. | Wang X et al. | β | 2016 | β |
| ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. | Kang EY et al. | β | 2016 | β |
| Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. | Lesseur C et al. | β | 2016 | β |
| Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity. | Petros Z et al. | β | 2016 | β |
| Genome-wide association studies and resting heart rate. | KilpelΓ€inen TO | β | 2016 | β |
| Genome-wide association studies of growth traits in three dairy cattle breeds using whole-genome sequence data. | Mao X et al. | β | 2016 | β |
| Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. | Hou L et al. | β | 2016 | β |
| Genome-wide gene-environment interactions on quantitative traits using family data. | Sitlani CM et al. | β | 2016 | β |
| Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. | Traylor M et al. | β | 2016 | β |
| GWAS analysis implicates NF-ΞΊB-mediated induction of inflammatory T cells in multiple sclerosis. | Hussman JP et al. | β | 2016 | β |
| Identifying genetic loci affecting antidepressant drug response in depression using drug-gene interaction models. | Noordam R et al. | β | 2016 | β |
| Imputing Phenotypes for Genome-wide Association Studies. | Hormozdiari F et al. | β | 2016 | β |
| Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS. | Wang Y et al. | β | 2016 | β |
| Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. | NINDS Stroke Genetics Network (SiGN) et al. | β | 2016 | β |
| Meta-analysis for genome-wide association studies using case-control design: application and practice. | Shim S et al. | β | 2016 | β |
| Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. | Cook JP et al. | β | 2016 | β |
| Population genomics of divergence within an obligate pollination mutualism: Selection maintains differences between Joshua tree species. | Royer AM et al. | β | 2016 | β |
| Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray. | Coleman JR et al. | β | 2016 | β |
| Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. | van 't Hof FN et al. | β | 2016 | β |
| Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. | Zhang M et al. | β | 2016 | β |
| Type 2 diabetes: genetic data sharing to advance complex disease research. | Flannick J et al. | β | 2016 | β |
| Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. | Fall T et al. | β | 2015 | β |
| A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. | Hirokawa M et al. | β | 2015 | β |
| A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. | Cho MH et al. | β | 2015 | β |
| Association of ADIPOQ gene with type 2 diabetes and related phenotypes in African American men and women: the Jackson Heart Study. | Davis SK et al. | β | 2015 | β |
| Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study. | Medina-Gomez C et al. | β | 2015 | β |
| Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma. | Ye Z et al. | β | 2015 | β |
| Comparative genome-wide association studies of a depressive symptom phenotype in a repeated measures setting by race/ethnicity in the Multi-Ethnic Study of Atherosclerosis. | Ware EB et al. | β | 2015 | β |
| Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies. | Nyholt DR et al. | β | 2015 | β |
| Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort. | Riestra P et al. | β | 2015 | β |
| Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models. | Fan R et al. | β | 2015 | β |
| Generalized estimating equations for genome-wide association studies using longitudinal phenotype data. | Sitlani CM et al. | β | 2015 | β |
| Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. | Bentham J et al. | β | 2015 | β |
| Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration. | Lanktree MB et al. | β | 2015 | β |
| Genetics and brain morphology. | Strike LT et al. | β | 2015 | β |
| Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. | Hayes MG et al. | β | 2015 | β |
| Genome-wide association study of prostate cancer-specific survival. | Szulkin R et al. | β | 2015 | β |
| Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. | Law MH et al. | β | 2015 | β |
| Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. | Adkins DE et al. | β | 2015 | β |
| Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence. | St Pourcain B et al. | β | 2015 | β |
| Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study. | Noordam R et al. | β | 2015 | β |
| Impact of genetic similarity on imputation accuracy. | Roshyara NR et al. | β | 2015 | β |
| Improving accuracy of rare variant imputation with a two-step imputation approach. | Kreiner-MΓΈller E et al. | β | 2015 | β |
| IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. | Lee JH et al. | β | 2015 | β |
| Letter: PNPLA3 and alcoholic liver disease--an alert to methodological limitations. Authors' reply. | Chamorro AJ et al. | β | 2015 | β |
| Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. | Li YR et al. | β | 2015 | β |
| Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load. | McLaren PJ et al. | β | 2015 | β |
| Population-specific genotype imputations using minimac or IMPUTE2. | van Leeuwen EM et al. | β | 2015 | β |
| Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array. | Dankowski T et al. | β | 2015 | β |
| Systematic assessment of imputation performance using the 1000 Genomes reference panels. | Liu Q et al. | β | 2015 | β |
| Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function. | Luo XJ et al. | β | 2015 | β |
| Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases. | Lenz TL et al. | β | 2015 | β |
| Accounting for linkage disequilibrium in association analysis of diverse populations. | Charles BA et al. | β | 2014 | β |
| A genome-wide association study of renal cell carcinoma among African Americans. | Purdue MP et al. | β | 2014 | β |
| A joint analysis to identify loci underlying variation in nematode resistance in three European sheep populations. | Riggio V et al. | β | 2014 | β |
| An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions. | Sung YJ et al. | β | 2014 | β |
| Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. | Lundby A et al. | β | 2014 | β |
| Association mapping in crop plants: opportunities and challenges. | Gupta PK et al. | β | 2014 | β |
| Axonal guidance signaling pathway interacting with smoking in modifying the risk of pancreatic cancer: a gene- and pathway-based interaction analysis of GWAS data. | Tang H et al. | β | 2014 | β |
| C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. | Diekstra FP et al. | β | 2014 | β |
| DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. | Lee JH et al. | β | 2014 | β |
| fcGENE: a versatile tool for processing and transforming SNP datasets. | Roshyara NR et al. | β | 2014 | β |
| Gene-based rare allele analysis identified a risk gene of Alzheimer's disease. | Kim JH et al. | β | 2014 | β |
| Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. | Tragante V et al. | β | 2014 | β |
| Genes-environment interactions in obesity- and diabetes-associated pancreatic cancer: a GWAS data analysis. | Tang H et al. | β | 2014 | β |
| Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. | Lee JH et al. | β | 2014 | β |
| Genome-wide analysis of the heritability of amyotrophic lateral sclerosis. | Keller MF et al. | β | 2014 | β |
| Genome-wide association study identifies multiple loci associated with bladder cancer risk. | Figueroa JD et al. | β | 2014 | β |
| Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. | Wolpin BM et al. | β | 2014 | β |
| Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome. | Holliday EG et al. | β | 2014 | β |
| Genome-wide association study reveals two new risk loci for bipolar disorder. | MΓΌhleisen TW et al. | β | 2014 | β |
| Genome-wide association study using high-density single nucleotide polymorphism arrays and whole-genome sequences for clinical mastitis traits in dairy cattle. | Sahana G et al. | β | 2014 | β |
| Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. | Mayes MD et al. | β | 2014 | β |
| Impact of pre-imputation SNP-filtering on genotype imputation results. | Roshyara NR et al. | β | 2014 | β |
| InterPregGen: genetic studies of pre-eclampsia in three continents. | Morgan L et al. | β | 2014 | β |
| Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. | Nalls MA et al. | β | 2014 | β |
| Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12. | Kilarski LL et al. | β | 2014 | β |
| On individual genome-wide association studies and their meta-analysis. | Pei YF et al. | β | 2014 | β |
| PhenoMan: phenotypic data exploration, selection, management and quality control for association studies of rare and common variants. | Li B et al. | β | 2014 | β |
| Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. | Lee JH et al. | β | 2014 | β |
| Practical aspects of genome-wide association interaction analysis. | Gusareva ES et al. | β | 2014 | β |
| Prenatal and postnatal genetic influence on lung function development. | Kreiner-MΓΈller E et al. | β | 2014 | β |
| QCGWAS: A flexible R package for automated quality control of genome-wide association results. | van der Most PJ et al. | β | 2014 | β |
| Quality control and conduct of genome-wide association meta-analyses. | Winkler TW et al. | β | 2014 | β |
| Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. | Cho MH et al. | β | 2014 | β |
| SUCLG2 identified as both a determinator of CSF AΞ²1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. | Ramirez A et al. | β | 2014 | β |
| Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations. | Li YR et al. | β | 2014 | β |
| A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12. | Fernandez-Rozadilla C et al. | β | 2013 | β |
| A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility. | Meredith BK et al. | β | 2013 | β |
| A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. | Yamazaki K et al. | β | 2013 | β |
| A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12. | Shi Y et al. | β | 2013 | β |
| A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. | Lane J et al. | β | 2013 | β |
| A mega-analysis of genome-wide association studies for major depressive disorder. | Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium et al. | β | 2013 | β |
| Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology. | Heilmann S et al. | β | 2013 | β |
| Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis. | Zhao Z et al. | β | 2013 | β |
| Common variation contributes to the genetic architecture of social communication traits. | St Pourcain B et al. | β | 2013 | β |
| Development and application of genomic control methods for genome-wide association studies using non-additive models. | Tsepilov YA et al. | β | 2013 | β |
| Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches. | Sul JH et al. | β | 2013 | β |
| Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. | Hutter CM et al. | β | 2013 | β |
| Genetics and epigenetics of rheumatoid arthritis. | Viatte S et al. | β | 2013 | β |
| Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis. | Parry HM et al. | β | 2013 | β |
| Genome-wide association analysis identifies 13 new risk loci for schizophrenia. | Ripke S et al. | β | 2013 | β |
| Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. | Cui J et al. | β | 2013 | β |
| Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. | Chen DT et al. | β | 2013 | β |
| Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations. | Wheeler HE et al. | β | 2013 | β |
| Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D. | Adkins DE et al. | β | 2013 | β |
| GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. | Rietveld CA et al. | β | 2013 | β |
| Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. | Cross-Disorder Group of the Psychiatric Genomics Consortium | β | 2013 | β |
| Imputation-based meta-analysis of severe malaria in three African populations. | Band G et al. | β | 2013 | β |
| Imputation of coding variants in African Americans: better performance using data from the exome sequencing project. | Duan Q et al. | β | 2013 | β |
| Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. | Holliday EG et al. | β | 2013 | β |
| Inter-chromosomal level of genome organization and longevity-related phenotypes in humans. | Kulminski AM et al. | β | 2013 | β |
| Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies. | Joshi PK et al. | β | 2013 | β |
| Loci influencing blood pressure identified using a cardiovascular gene-centric array. | Ganesh SK et al. | β | 2013 | β |
| Meta-analysis methods for genome-wide association studies and beyond. | Evangelou E et al. | β | 2013 | β |
| Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1. | Stewart SE et al. | β | 2013 | β |
| Meta-analysis of gene-level associations for rare variants based on single-variant statistics. | Hu YJ et al. | β | 2013 | β |
| MetaSeq: privacy preserving meta-analysis of sequencing-based association studies. | Singh AP et al. | β | 2013 | β |
| Partial support for ZNF804A genotype-dependent alterations in prefrontal connectivity. | Paulus FM et al. | β | 2013 | β |
| Pleiotropy in complex traits: challenges and strategies. | Solovieff N et al. | β | 2013 | β |
| Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. | Diogo D et al. | β | 2013 | β |
| Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. | Vijai J et al. | β | 2013 | β |
| The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort. | Astermark J et al. | β | 2013 | β |
| The power of meta-analysis in genome-wide association studies. | Panagiotou OA et al. | β | 2013 | β |
| The role of 39 psoriasis risk variants on age of psoriasis onset. | Lu Y et al. | β | 2013 | β |
| The value of statistical or bioinformatics annotation for rare variant association with quantitative trait. | Byrnes AE et al. | β | 2013 | β |
| 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. | Huang J et al. | β | 2012 | β |
| A coalescent model for genotype imputation. | Jewett EM et al. | β | 2012 | β |
| A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. | Cho MH et al. | β | 2012 | β |
| Assessment of genotype imputation performance using 1000 Genomes in African American studies. | Hancock DB et al. | β | 2012 | β |
| Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. | MΓΌhleisen TW et al. | β | 2012 | β |
| Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. | Bakken TE et al. | β | 2012 | β |
| Association study of AGER gene polymorphism and hypertension in Han Chinese population. | Yang S et al. | β | 2012 | β |
| Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. | Ellinghaus D et al. | β | 2012 | β |
| Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. | Holliday EG et al. | β | 2012 | β |
| Comprehensive evaluation of imputation performance in African Americans. | Chanda P et al. | β | 2012 | β |
| Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs. | Krithika S et al. | β | 2012 | β |
| Follow-up study of the first genome-wide association scan in alopecia areata: IL13 and KIAA0350 as susceptibility loci supported with genome-wide significance. | Jagielska D et al. | β | 2012 | β |
| Genetic architectures of psychiatric disorders: the emerging picture and its implications. | Sullivan PF et al. | β | 2012 | β |
| Genetic origins of low birth weight. | Yaghootkar H et al. | β | 2012 | β |
| Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. | Lan Q et al. | β | 2012 | β |
| Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups. | Urayama KY et al. | β | 2012 | β |
| Genome-wide meta-analyses of smoking behaviors in African Americans. | David SP et al. | β | 2012 | β |
| Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects. | Sung YJ et al. | β | 2012 | β |
| Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative. | Liu EY et al. | β | 2012 | β |
| GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data. | Fuchsberger C et al. | β | 2012 | β |
| High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. | Eyre S et al. | β | 2012 | β |
| Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations. | Furlotte NA et al. | β | 2012 | β |
| Individual differences in amygdala-medial prefrontal anatomy link negative affect, impaired social functioning, and polygenic depression risk. | Holmes AJ et al. | β | 2012 | β |
| Insights into pancreatic cancer etiology from pathway analysis of genome-wide association study data. | Wei P et al. | β | 2012 | β |
| Interpreting meta-analyses of genome-wide association studies. | Han B et al. | β | 2012 | β |
| Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. | Asselbergs FW et al. | β | 2012 | β |
| Meta-analysis identifies common variants associated with body mass index in east Asians. | Wen W et al. | β | 2012 | β |
| Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. | Okada Y et al. | β | 2012 | β |
| Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. | Okada Y et al. | β | 2012 | β |
| Meta-analysis identifies six new susceptibility loci for atrial fibrillation. | Ellinor PT et al. | β | 2012 | β |
| Meta-analysis of untargeted metabolomic data from multiple profiling experiments. | Patti GJ et al. | β | 2012 | β |
| Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence. | GΓΆgele M et al. | β | 2012 | β |
| Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. | Lee PH et al. | β | 2012 | β |
| Multiple loci associated with renal function in African Americans. | Shriner D et al. | β | 2012 | β |
| Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. | Butler AM et al. | β | 2012 | β |
| Performance of genotype imputations using data from the 1000 Genomes Project. | Sung YJ et al. | β | 2012 | β |
| Polymorphisms of the SAMHD1 gene are not associated with the infection and natural control of HIV type 1 in Europeans and African-Americans. | Coon S et al. | β | 2012 | β |
| Population-based case-control association studies. | Hancock DB et al. | β | 2012 | β |
| Quick, "imputation-free" meta-analysis with proxy-SNPs. | Meesters C et al. | β | 2012 | β |
| Replication of a genome-wide association study of birth weight in preterm neonates. | Ryckman KK et al. | β | 2012 | β |
| The impact of imputation on meta-analysis of genome-wide association studies. | Li J et al. | β | 2012 | β |
| Travelling the world of gene-gene interactions. | Steen KV | β | 2012 | β |
| Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. | Kurreeman FA et al. | β | 2012 | β |
| A genome-wide association study of aging. | Walter S et al. | β | 2011 | β |
| A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. | Garcia-Closas M et al. | β | 2011 | β |
| A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region. | Png E et al. | β | 2011 | β |
| A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. | Surakka I et al. | β | 2011 | β |
| An empirical evaluation of imputation accuracy for association statistics reveals increased type-I error rates in genome-wide associations. | Almeida MA et al. | β | 2011 | β |
| Basic statistical analysis in genetic case-control studies. | Clarke GM et al. | β | 2011 | β |
| Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. | LindstrΓΆm S et al. | β | 2011 | β |
| Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. | Yu Y et al. | β | 2011 | β |
| Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles. | Chen PL et al. | β | 2011 | β |
| Converging evidence for an association of ATP2B2 allelic variants with autism in male subjects. | Carayol J et al. | β | 2011 | β |
| Fine mapping the TAGAP risk locus in rheumatoid arthritis. | Chen R et al. | β | 2011 | β |
| Gene- or region-based association study via kernel principal component analysis. | Gao Q et al. | β | 2011 | β |
| Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset. | Jin Y et al. | β | 2011 | β |
| Genome-wide association studies of antidepressant outcome: a brief review. | Laje G et al. | β | 2011 | β |
| Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. | Li YJ et al. | β | 2011 | β |
| Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. | Cichon S et al. | β | 2011 | β |
| Genome-wide association study identifies new prostate cancer susceptibility loci. | Schumacher FR et al. | β | 2011 | β |
| Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. | Purdue MP et al. | β | 2011 | β |
| Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. | Patsopoulos NA et al. | β | 2011 | β |
| Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. | Fan Q et al. | β | 2011 | β |
| Genotype imputation with thousands of genomes. | Howie B et al. | β | 2011 | β |
| GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma. | Smedby KE et al. | β | 2011 | β |
| Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. | Reilly MP et al. | β | 2011 | β |
| Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. | International Parkinson Disease Genomics Consortium et al. | β | 2011 | β |
| Lack of replication in polymorphisms reported to be associated with atrial fibrillation. | Sinner MF et al. | β | 2011 | β |
| Mapping rare and common causal alleles for complex human diseases. | Raychaudhuri S | β | 2011 | β |
| Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. | Hu X et al. | β | 2011 | β |
| Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. | Liu Y et al. | β | 2011 | β |
| Meta-analysis of genome-wide association for migraine in six population-based European cohorts. | Ligthart L et al. | β | 2011 | β |
| Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. | Zhernakova A et al. | β | 2011 | β |
| Methods for testing association between uncertain genotypes and quantitative traits. | Kutalik Z et al. | β | 2011 | β |
| Multi-ethnic studies in complex traits. | Fu J et al. | β | 2011 | β |
| Multilocus genetic analysis of brain images. | Hibar DP et al. | β | 2011 | β |
| Multiple loci are associated with white blood cell phenotypes. | Nalls MA et al. | β | 2011 | β |
| New IBD genetics: common pathways with other diseases. | Lees CW et al. | β | 2011 | β |
| Novel genetic variation in exon 28 of FBN1 gene is associated with essential hypertension. | Shen C et al. | β | 2011 | β |
| Optimal methods for meta-analysis of genome-wide association studies. | Zhou B et al. | β | 2011 | β |
| Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. | Bennett SN et al. | β | 2011 | β |
| Progress and promise of genome-wide association studies for human complex trait genetics. | Stranger BE et al. | β | 2011 | β |
| Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. | Han B et al. | β | 2011 | β |
| Strategies for genetic model specification in the screening of genome-wide meta-analysis signals for further replication. | Pereira TV et al. | β | 2011 | β |
| The meta-analysis of genome-wide association studies. | Thompson JR et al. | β | 2011 | β |
| The use of imputed values in the meta-analysis of genome-wide association studies. | Jiao S et al. | β | 2011 | β |
| A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. | Newman AB et al. | β | 2010 | β |
| A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. | Rothman N et al. | β | 2010 | β |
| A new statistic to evaluate imputation reliability. | Lin P et al. | β | 2010 | β |
| An extended IUPAC nomenclature code for polymorphic nucleic acids. | Johnson AD | β | 2010 | β |
| A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. | Abnet CC et al. | β | 2010 | β |
| Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. | Sotoodehnia N et al. | β | 2010 | β |
| Common variants in KCNN3 are associated with lone atrial fibrillation. | Ellinor PT et al. | β | 2010 | β |
| Dealing with missing values in large-scale studies: microarray data imputation and beyond. | Aittokallio T | β | 2010 | β |
| Evoker: a visualization tool for genotype intensity data. | Morris JA et al. | β | 2010 | β |
| FGF21 signalling pathway and metabolic traits - genetic association analysis. | Kaess BM et al. | β | 2010 | β |
| Genome-wide association analysis identifies multiple loci related to resting heart rate. | Eijgelsheim M et al. | β | 2010 | β |
| Genome-wide association analysis identifies three psoriasis susceptibility loci. | Stuart PE et al. | β | 2010 | β |
| Genome-wide association identifies multiple ulcerative colitis susceptibility loci. | McGovern DP et al. | β | 2010 | β |
| Genome-wide association studies: a primer. | Corvin A et al. | β | 2010 | β |
| Genome-wide association studies--data generation, storage, interpretation, and bioinformatics. | Pare G | β | 2010 | β |
| Genome-wide association studies in diverse populations. | Rosenberg NA et al. | β | 2010 | β |
| Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study. | Tang W et al. | β | 2010 | β |
| Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. | Stahl EA et al. | β | 2010 | β |
| Genome-wide association study of intracranial aneurysm identifies three new risk loci. | Yasuno K et al. | β | 2010 | β |
| Genome-wide meta-analyses identify multiple loci associated with smoking behavior. | Tobacco and Genetics Consortium | β | 2010 | β |
| Genome-wide meta-analysis of joint tests for genetic and gene-environment interaction effects. | Aschard H et al. | β | 2010 | β |
| Genotype imputation for genome-wide association studies. | Marchini J et al. | β | 2010 | β |
| GWAMA: software for genome-wide association meta-analysis. | MΓ€gi R et al. | β | 2010 | β |
| IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. | International Multiple Sclerosis Genetics Conssortium (IMSGC) | β | 2010 | β |
| Imputation aware meta-analysis of genome-wide association studies. | Zaitlen N et al. | β | 2010 | β |
| Introduction to linkage disequilibrium, the HapMap, and imputation. | Neale BM | β | 2010 | β |
| Meta-analysis and imputation refines the association of 15q25 with smoking quantity. | Liu JZ et al. | β | 2010 | β |
| Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. | Neale BM et al. | β | 2010 | β |
| METAL: fast and efficient meta-analysis of genomewide association scans. | Willer CJ et al. | β | 2010 | β |
| Pharmacogenetics of drug-induced liver injury. | Russmann S et al. | β | 2010 | β |
| Principal-component analysis for assessment of population stratification in mitochondrial medical genetics. | Biffi A et al. | β | 2010 | β |
| Prioritizing GWAS results: A review of statistical methods and recommendations for their application. | Cantor RM et al. | β | 2010 | β |
| Progress in the genetics of common obesity and type 2 diabetes. | Vimaleswaran KS et al. | β | 2010 | β |
| Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation. | Kim ST et al. | β | 2010 | β |
| Recent advances in the genetics of rheumatoid arthritis. | Raychaudhuri S | β | 2010 | β |
| Support of association between BRD1 and both schizophrenia and bipolar affective disorder. | Nyegaard M et al. | β | 2010 | β |
| The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. | Hsiung CA et al. | β | 2010 | β |
| The PCLO gene and depressive disorders: replication in a population-based study. | Hek K et al. | β | 2010 | β |
| The psychiatric GWAS consortium: big science comes to psychiatry. | Sullivan PF | β | 2010 | β |
| The pursuit of genome-wide association studies: where are we now? | Ku CS et al. | β | 2010 | β |
| To identify associations with rare variants, just WHaIT: Weighted haplotype and imputation-based tests. | Li Y et al. | β | 2010 | β |
| Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. | Freathy RM et al. | β | 2010 | β |
| A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. | Song H et al. | β | 2009 | β |
| A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. | Estrada K et al. | β | 2009 | β |
| A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. | Browning BL et al. | β | 2009 | β |
| Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. | Richards JB et al. | β | 2009 | β |
| Common genetic variants on 5p14.1 associate with autism spectrum disorders. | Wang K et al. | β | 2009 | β |
| Data integration in genetics and genomics: methods and challenges. | Hamid JS et al. | β | 2009 | β |
| Effects of normalization on quantitative traits in association test. | Goh L et al. | β | 2009 | β |
| FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. | Udler MS et al. | β | 2009 | β |
| Genetic structure of Europeans: a view from the North-East. | Nelis M et al. | β | 2009 | β |
| Genetic variation in NOS1AP is associated with sudden cardiac death: evidence from the Rotterdam Study. | Eijgelsheim M et al. | β | 2009 | β |
| Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. | Lindgren CM et al. | β | 2009 | β |
| Genome-wide association studies--a summary for the clinical gastroenterologist. | Melum E et al. | β | 2009 | β |
| Genome-wide association studies: quality control and population-based measures. | Ziegler A | β | 2009 | β |
| Genomewide association study for onset age in Parkinson disease. | Latourelle JC et al. | β | 2009 | β |
| Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. | van Es MA et al. | β | 2009 | β |
| Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. | Hancock DB et al. | β | 2009 | β |
| Genome-wide linkage and follow-up association study of postpartum mood symptoms. | Mahon PB et al. | β | 2009 | β |
| Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. | Hazra A et al. | β | 2009 | β |
| GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data. | Estrada K et al. | β | 2009 | β |
| HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. | Daly AK et al. | β | 2009 | β |
| IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis. | Li MX et al. | β | 2009 | β |
| Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. | De Jager PL et al. | β | 2009 | β |
| Meta-analysis of genome-wide association studies with overlapping subjects. | Lin DY et al. | β | 2009 | β |
| Recent progress in the genetics of common obesity. | Loos RJ | β | 2009 | β |
| Replication in genome-wide association studies. | Kraft P et al. | β | 2009 | β |
| Single-nucleotide polymorphism bioinformatics: a comprehensive review of resources. | Johnson AD | β | 2009 | β |
| The relationship between imputation error and statistical power in genetic association studies in diverse populations. | Huang L et al. | β | 2009 | β |
| Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. | Rivadeneira F et al. | β | 2009 | β |
| Validating, augmenting and refining genome-wide association signals. | Ioannidis JP et al. | β | 2009 | β |