METAL: fast and efficient meta-analysis of genomewide association scans.
paper
Cited
Public
- Authors
- Willer, Cristen J; Li, Yun; Abecasis, Gonçalo R
- Year
- 2010
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 20616382
- DOI
- 10.1093/bioinformatics/btq340
- PMCID
- PMC2922887
SUMMARY: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies. METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats. AVAILABILITY AND IMPLEMENTATION: METAL, including source code, documentation, examples, and executables, is available at http://www.sph.umich.edu/csg/abecasis/metal/.
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| # | Section | Preview |
|---|---|---|
| 0 | 1 INTRODUCTION | Meta-analysis is becoming an increasingly important tool in genome-wide association studies (GWAS)β¦ |
| 1 | 1 INTRODUCTION | Meta-analysis of genome-wide association summary statistics, in contrast to direct analysis of⦠|
| 2 | 2 METHODS | The basic principle of meta-analysis is to combine the evidence for association from individual⦠|
| 3 | 2 METHODS | very flexible and allows results to be combined even when effect size estimates are not available or⦠|
| 4 | 3 RESULTS β 3.1 Implementation | In implementing our software for meta-analysis, a primary consideration was to facilitateβ¦ |
| 5 | 3 RESULTS β 3.2 Usage | METAL has been used extensively by many groups since its initial release in January 2008. This fieldβ¦ |
| 6 | 3 RESULTS β 3.2 Usage | option to estimate a genomic control parameter (Devlin and Roeder, 1999) for each input file andβ¦ |
| 7 | 3 RESULTS β 3.3 Performance | METAL was written in C++ and is freely available for download. METAL compiles and runs on most Unixβ¦ |
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| Cross-Phenotype Genome-Wide Association Study on the Shared Genetic Susceptibility to Systemic Sclerosis and Primary Biliary Cholangitis. | Luo Y et al. | β | 2025 | β |
| Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation. | Yuan S et al. | β | 2025 | β |
| Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations. | Kho PF et al. | β | 2025 | β |
| Data simulation to optimize frameworks for genome-wide association studies in diverse populations. | Mugo JW et al. | β | 2025 | β |
| Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing. | Pottier C et al. | β | 2025 | β |
| Deciphering gene-smoking interactions in age-related macular degeneration through cross-biobank genomic integration. | Guo J et al. | β | 2025 | β |
| Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization. | Xia C et al. | β | 2025 | β |
| Decomposing the genetic background of chronic back pain. | Elgaeva EE et al. | β | 2025 | β |
| Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations. | Onyenobi E et al. | β | 2025 | β |
| Differences and similarities between the genetic architecture of lifetime substance use across different substances. | Bright U et al. | β | 2025 | β |
| Discovery of obesity genes through cross-ancestry analysis. | Banerjee D et al. | β | 2025 | β |
| Dissecting the Genetic Architecture of Intracranial Aneurysms. | Adkar SS et al. | β | 2025 | β |
| Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease. | Trenkwalder T et al. | β | 2025 | β |
| Diversity and longitudinal records: Genetic architecture of disease associations and polygenic risk in the Taiwanese Han population. | Liu TY et al. | β | 2025 | β |
| Divide and conquer approach for genome-wide association studies. | Γzkaraca MΔ° et al. | β | 2025 | β |
| DNA methylation landscapes of HIV controllers: an epigenome-wide association study. | Gupta MK et al. | β | 2025 | β |
| Early lipid genetics: identification of common and rare genetic variants for lipid traits in Indian adolescents. | Nair JM et al. | β | 2025 | β |
| Effects of Genetic Risk and Lifestyle Habits on Gout: A Korean Cohort Study. | Kim H et al. | β | 2025 | β |
| Elucidation and application of the neuroimmune axis between depression and autoimmune diseases: A genome wide and cohort study. | Sun F et al. | β | 2025 | β |
| Enhancer of TRPS1 rs12549956 Influences Hair Thickness in Chinese Populations. | Qian Q et al. | β | 2025 | β |
| EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis. | Wang L et al. | β | 2025 | β |
| Epigenome-Wide Analysis Identifies Pollution-Sensitive Loci in Fibrotic Interstitial Lung Disease. | Goobie GC et al. | β | 2025 | β |
| Epigenome-wide association study of cerebrospinal fluid-based biomarkers of Alzheimer's disease in cognitively normal individuals. | HΓΌls A et al. | β | 2025 | β |
| Epigenome-wide association study of objectively measured physical activity in peripheral blood leukocytes. | Fragoso-Bargas N et al. | β | 2025 | β |
| Evaluating metabolome-wide causal effects on risk for psychiatric and neurodegenerative disorders. | Gilchrist L et al. | β | 2025 | β |
| Evaluating multi-ancestry genome-wide association methods: Statistical power, population structure, and practical implications. | Dias JA et al. | β | 2025 | β |
| Exome and Genome Sequencing Reveals Novel Variants for Severe Diabetic Retinopathy in Type 1 Diabetes. | Vuori N et al. | β | 2025 | β |
| Exploring the genomic and transcriptomic profiles of glycemic traits and drug repurposing. | Lin MR et al. | β | 2025 | β |
| Exploring the role of circulating proteins in multiple myeloma risk: a Mendelian randomization study. | Lee MA et al. | β | 2025 | β |
| Exploring the Role of Glycine Metabolism in Coronary Artery Disease: Insights from Human Genetics and Mouse Models. | Biswas S et al. | β | 2025 | β |
| fastMETA: a fast and efficient tool for multivariate meta-analysis of GWAS. | Manios GA et al. | β | 2025 | β |
| Fine-mapping genomic loci refines bipolar disorder risk genes. | Koromina M et al. | β | 2025 | β |
| FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries. | Wonkam A et al. | β | 2025 | β |
| Functional variant at 19q13.3 confers nonsyndromic cleft palate susceptibility by regulating <i>HIF3A</i>. | Lou S et al. | β | 2025 | β |
| Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer. | Prizment A et al. | β | 2025 | β |
| GDBIG: A Pioneering Birth Cohort Genomic Platform Facilitating Intergenerational Genetic Research. | Huang S et al. | β | 2025 | β |
| Gene-Smoking Interaction in Insulin Sensitivity and Ξ²-Cell Function Among Normal Glucose Tolerance Individuals. | Gu P et al. | β | 2025 | β |
| Genetic analyses of eight complex diseases using predicted continuous representations of disease. | Chen R et al. | β | 2025 | β |
| Genetic analysis in African ancestry populations reveals genetic contributors to lung cancer susceptibility. | Betti MJ et al. | β | 2025 | β |
| Genetic and epidemiologic assessment of mandibular cortical indices and bone mineral density in peripubertal children: the Generation R study. | Prijatelj V et al. | β | 2025 | β |
| Genetic and neural mechanisms shared by schizophrenia and depression. | Xie Y et al. | β | 2025 | β |
| Genetic architecture and risk prediction of gestational diabetes mellitus in Chinese pregnancies. | Gu Y et al. | β | 2025 | β |
| Genetic Architecture of Cerebral White Matter Hyperintensities in Diverse Hispanic/Latino Adults. | Fornage M et al. | β | 2025 | β |
| Genetic associations between orexin genes and phenotypes related to behavioral regulation in humans, including substance use. | Aliev F et al. | β | 2025 | β |
| Genetic association studies using disease liabilities from deep neural networks. | Yang L et al. | β | 2025 | β |
| Genetic associations with educational fields. | Cheesman R et al. | β | 2025 | β |
| Genetic characterization of preschool wheeze phenotypes. | Fischer-Rasmussen K et al. | β | 2025 | β |
| Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases. | Sadler MC et al. | β | 2025 | β |
| Genetic Discovery and Risk Prediction for Type 1 Diabetes in Individuals Without High-Risk HLA-DR3/DR4 Haplotypes. | McGrail C et al. | β | 2025 | β |
| Genetic effects on gestational diabetes mellitus and their interactions with environmental factors among Japanese women. | Kawahara T et al. | β | 2025 | β |
| Genetic insights into cardiac conduction disorders from genome-wide association studies. | Li B et al. | β | 2025 | β |
| Genetic insights into CRP levels in Indian adolescents: confirming adult genetic associations. | Nair JM et al. | β | 2025 | β |
| Genetic insights into cytokine-thrombosis cross-talk: an integrated multi-omics network analysis. | Zhou W et al. | β | 2025 | β |
| Genetic liability to psoriasis predicts severe disease outcomes. | Saklatvala JR et al. | β | 2025 | β |
| Genetic Links Between Subcortical Brain Morphometry and Suicide Attempt Risk in Children and Adults. | Ceja Z et al. | β | 2025 | β |
| Genetic mapping of a chickpea (Cicer arietinum L.) diversity panel for mineral biofortification towards human nutrition. | Salaria S et al. | β | 2025 | β |
| Genetic mapping of serum metabolome to chronic diseases among Han Chinese. | Cheng C et al. | β | 2025 | β |
| Genetic modifiers of asthma response to air pollution in children: An African ancestry GWAS and PM<sub>2.5</sub> polygenic risk score study. | Kelchtermans J et al. | β | 2025 | β |
| Genetic modulation of lncPSMB1 confers non-syndromic cleft lip with or without cleft palate susceptibility by promoting cell apoptosis. | Li X et al. | β | 2025 | β |
| Genetic relationship between epilepsy and mental disorders: A comprehensive GWAS analysis. | Abudusalamu R et al. | β | 2025 | β |
| Genetic relationships between systemic lupus erythematosus and a positive antinuclear antibody test in the absence of autoimmune disease. | Khan A et al. | β | 2025 | β |
| Genetic risk for alcohol use disorder in relation to individual symptom criteria: Do polygenic indices provide unique information for understanding severity and heterogeneity? | Sarles YM et al. | β | 2025 | β |
| Genetic risk for trait aggression and alcohol use predict unique facets of alcohol-related aggression. | Spychala KM et al. | β | 2025 | β |
| Genetic Risk Variants for Multiple Sclerosis and Other Loci Linked to Intrathecal Immunoglobulin G Synthesis. | Pukaj A et al. | β | 2025 | β |
| Genetics of Childhood-Onset Systemic Lupus Erythematosus. | Carlomagno R et al. | β | 2025 | β |
| Genetics of C-Peptide and Age at Diagnosis in Type 1 Diabetes. | Roshandel D et al. | β | 2025 | β |
| Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes. | Assary E et al. | β | 2025 | β |
| Genetic study of intrahepatic cholestasis of pregnancy in Chinese women unveils East Asian etiology linked to historic HBV epidemic. | Liu Y et al. | β | 2025 | β |
| Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities. | Chami N et al. | β | 2025 | β |
| Genetic susceptibility to cerebral palsy involves complement system-mediated neuronal development and plasticity pathway. | Kun H et al. | β | 2025 | β |
| Genetic Susceptibility to Neurodevelopmental Conditions Is Associated With Neonatal DNA Methylation Patterns in the General Population: An Individual Participant Data Meta-Analysis. | Schuurmans IK et al. | β | 2025 | β |
| Genetic variants associated with chronic postsurgical pain: evidence from the China Surgery and Anaesthesia Cohort study. | Song J et al. | β | 2025 | β |
| Genetic Variants Associated With the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis. | Best CM et al. | β | 2025 | β |
| Genetic variants predisposing to an increased risk of kidney stone disease. | Lovegrove CE et al. | β | 2025 | β |
| Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum. | Venkatesh SS et al. | β | 2025 | β |
| Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder. | Strom NI et al. | β | 2025 | β |
| Genome-wide analysis identifies susceptibility loci for heart failure and nonischemic cardiomyopathy subtype in the East Asian populations. | Han Y et al. | β | 2025 | β |
| Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health. | Jawinski P et al. | β | 2025 | β |
| Genome-wide association analyses identify candidate loci for amyloid imaging and plasma biomarkers in adults with Down syndrome. | Aslam MM et al. | β | 2025 | β |
| Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression. | Shorter JR et al. | β | 2025 | β |
| Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations. | Underwood MI et al. | β | 2025 | β |
| Genome-wide association and multi-omics analyses provide insights into the disease mechanisms of central serous chorioretinopathy. | Mori Y et al. | β | 2025 | β |
| Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets. | Ricci A et al. | β | 2025 | β |
| Genome-wide association meta-analysis and rare copy number variant analysis of treatment-resistant depression. | Xiong Y et al. | β | 2025 | β |
| Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry. | Gui A et al. | β | 2025 | β |
| Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants. | FΓΆrster F et al. | β | 2025 | β |
| Genome-wide association, single-cell, and spatial transcriptomics analyses reveal the role of the STK24-expressing positive cells in LUAD progression and the tumor microenvironment, identifying STK24 as a potential therapeutic target. | Liu J et al. | β | 2025 | β |
| Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures. | Jee YH et al. | β | 2025 | β |
| Genome-wide association studies of Alzheimer's disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans. | Sherva R et al. | β | 2025 | β |
| Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B. | Godrich D et al. | β | 2025 | β |
| Genome-wide association study and HLA genotyping for beryllium disease susceptibility in a European descent population. | Liao SY et al. | β | 2025 | β |
| Genome-wide association study and Mendelian randomization analyses reveal insights into bladder cancer etiology. | Larsson SC et al. | β | 2025 | β |
| Genome-Wide Association Study and Meta-Analysis Uncovers Key Candidate Genes for Body Weight Traits in Chickens. | Wen J et al. | β | 2025 | β |
| Genome-wide association study and polygenic risk prediction of hypothyroidism. | Rand SA et al. | β | 2025 | β |
| Genome Wide Association Study (GWAS) Identifies Novel Genetic Loci for Second-Generation Antipsychotics (SGA)-Induced Metabolic Syndrome (MetS). | El Rouby N et al. | β | 2025 | β |
| Genome-wide association study identifies common variants associated with breast cancer in South African Black women. | Hayat M et al. | β | 2025 | β |
| Genome-wide association study identifies <i>ABCG1</i> as a susceptibility locus for tick-borne encephalitis. | Gampawar PG et al. | β | 2025 | β |
| Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. | Strom NI et al. | β | 2025 | β |
| Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes. | Henry A et al. | β | 2025 | β |
| Genome-wide association study meta-analysis uncovers novel genetic variants associated with olfactory dysfunction. | Imtiaz MA et al. | β | 2025 | β |
| Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer. | Barnes DR et al. | β | 2025 | β |
| Genome-wide association study of Asian women identifies putative mammographic density-associated loci. | Mariapun S et al. | β | 2025 | β |
| Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci. | Im C et al. | β | 2025 | β |
| Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium. | Dong M et al. | β | 2025 | β |
| Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program. | Raghavan S et al. | β | 2025 | β |
| Genome-Wide Association Study of Intraocular Pressure in Population-Based Cohorts in Japan: The Tohoku Medical Megabank Organization Eye Study. | Fuse N et al. | β | 2025 | β |
| Genome-Wide Association Study of Plasma Sodium Concentrations with and without Exposure to Thiazide Diuretics. | Andersson NW et al. | β | 2025 | β |
| Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups. | Hoffmann TJ et al. | β | 2025 | β |
| Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci. | Cole JB et al. | β | 2025 | β |
| Genome-wide association study of REM sleep behavior disorder in Parkinson's disease. | Sosero YL et al. | β | 2025 | β |
| Genome-wide association study of susceptibility to acute respiratory distress syndrome. | Guillen-Guio B et al. | β | 2025 | β |
| Genome-Wide Association Study of Temporomandibular Disorder-Related Pain in Finnish Populations. | Leppilahti JM et al. | β | 2025 | β |
| Genome-Wide Association Study of Varenicline-Aided Smoking Cessation. | Coley K et al. | β | 2025 | β |
| Genome-wide association study provides insights into the genetic basis of Lewy body dementia. | Zhu P et al. | β | 2025 | β |
| Genome-wide association study provides novel insight into the genetic architecture of severe obesity. | Krishnan M et al. | β | 2025 | β |
| Genome-Wide Association Study Reveals a Causal Relationship Between Allergic Rhinitis and Hazelnut Allergy. | Sun Y et al. | β | 2025 | β |
| Genome-wide association study reveals shared and distinct genetic architecture of fatty acids and oxylipins in the Hispanic Community Health Study/Study of Latinos. | Downie CG et al. | β | 2025 | β |
| Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function. | Valo E et al. | β | 2025 | β |
| Genome-Wide Meta-Analysis Identifies Five Single-Nucleotide Polymorphisms Associated With Both Vitiligo and Freckles in the Chinese Han Population. | Lu J et al. | β | 2025 | β |
| Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups. | Kim J et al. | β | 2025 | β |
| Genome-wide meta-analysis of heavy menstrual bleeding reveals 36 risk loci. | Thibord F et al. | β | 2025 | β |
| Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures. | Kang M et al. | β | 2025 | β |
| Genome-Wide Scan of Fifth Finger Clinodactyly. | Lee MK et al. | β | 2025 | β |
| Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood. | Jakubek YA et al. | β | 2025 | β |
| Genomic data-driven framework for drug target discovery in atrial fibrillation. | Tao Y et al. | β | 2025 | β |
| Genomic determinants of biological age estimated by deep learning applied to retinal images. | Huang Y et al. | β | 2025 | β |
| Genomic loci and molecular genetic mechanisms for hidradenitis suppurativa. | Broadaway KA et al. | β | 2025 | β |
| Genomics of chronic dry cough unravels neurological pathways. | Coley K et al. | β | 2025 | β |
| Genotype-by-sex interaction analyses for alcohol use disorder across biobanks. | Zhou H et al. | β | 2025 | β |
| Germline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity. | Sonehara K et al. | β | 2025 | β |
| GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology. | Luben RN et al. | β | 2025 | β |
| GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis. | Yuan S et al. | β | 2025 | β |
| GWAS meta-analysis identifies five susceptibility loci for endometrial cancer. | Ramachandran D et al. | β | 2025 | β |
| GWAS Meta-Analysis Identifies Susceptibility Loci for Keloids and Hypertrophic Scarring in Europeans. | Dand N et al. | β | 2025 | β |
| GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets. | Dand N et al. | β | 2025 | β |
| GWAS meta-analysis using a graph-based pan-genome enhanced gene mining efficiency for agronomic traits in rice. | Yang L et al. | β | 2025 | β |
| GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study. | Magavern EF et al. | β | 2025 | β |
| Host Genetic Variants Associated With Helicobacter pylori Infection: A Meta-Analysis Combined With Functional Annotation. | Zhao WJ et al. | β | 2025 | β |
| HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement. | Farashi S et al. | β | 2025 | β |
| Human CD33 deficiency is associated with mild alteration of circulating white blood cell counts. | Dominy J et al. | β | 2025 | β |
| Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases. | Bhak Y et al. | β | 2025 | β |
| Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses. | Willett JDS et al. | β | 2025 | β |
| Identification of 1q25.2 as a novel shared locus between schizophrenia and major depressive disorder in east Asians by integrative analyses. | Guo X et al. | β | 2025 | β |
| Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia. | Cabrera-Serrano AJ et al. | β | 2025 | β |
| Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging. | Jiang X et al. | β | 2025 | β |
| Identification of Endometriosis Pathophysiologic-Related Genes Based on Meta-Analysis and Bayesian Approach. | Kang J et al. | β | 2025 | β |
| Identification of genetic loci enriched in obese or lean T2D cases in the Korean population. | Lim EB et al. | β | 2025 | β |
| Identification of potential susceptibility loci for non-small cell lung cancer through whole genome sequencing in circadian rhythm genes. | Xu X et al. | β | 2025 | β |
| Identification of risk variants and cross-disorder pleiotropy through multi-ancestry genome-wide analysis of alcohol use disorder. | Icick R et al. | β | 2025 | β |
| Identification of therapeutic targets for insomnia through genetic and plasma proteomic approaches. | Wang X et al. | β | 2025 | β |
| Identified genetic locus for longitudinal disease activity in adults with systemic lupus erythematosus. | Misztal MC et al. | β | 2025 | β |
| Identifying common genetic etiologies between iridocyclitis and related immune-mediated diseases. | Liu Z et al. | β | 2025 | β |
| Immune and metabolic disturbance as a function of genetic risk and phase of illness in major depression. | Howard DM et al. | β | 2025 | β |
| Immune cell-based transcriptomic Mendelian randomization and colocalization study on type 1 diabetes. | Sklar J et al. | β | 2025 | β |
| Improved Annotation of Asthma Gene Variants with Cell Type Deconvolution of Nasal and Lung Expression Quantitative Trait Loci. | El-Husseini ZW et al. | β | 2025 | β |
| Improving reproducibility of differentially expressed genes in single-cell transcriptomic studies of neurodegenerative diseases through meta-analysis. | Nakatsuka N et al. | β | 2025 | β |
| Insights Into Chronic Low Back Pain Etiology: Population-Based Genome-Wide Association Study Identifies 18 Risk Loci. | Martinsen AE et al. | β | 2025 | β |
| Integrated genome-wide association studies, meta-analysis, and Bayesian fine mapping reveal novel quantitative trait loci's and functional candidate genes for vulva traits in large white pigs. | Zhou J et al. | β | 2025 | β |
| Integrated multi-omics analysis reveals AKR1C1 as a key mediator of intervertebral disc degeneration: protecting against ferroptosis via PI3K/AKT signaling. | Feng J et al. | β | 2025 | β |
| Integrating eQTL and genome-wide association studies to uncover additive and dominant regulatory circuits in pig uterine capacity. | Xu Z et al. | β | 2025 | β |
| Integrating exosome wide associations study and Mendelian randomization identified causal miRNAs for type 2 diabetes mellitus and its complications. | Li DL et al. | β | 2025 | β |
| Integrating genome-wide and epigenome-wide associations for antipsychotic induced extrapyramidal side effects. | Yao K et al. | β | 2025 | β |
| Integrating genome-wide information and wearable device data to explore the link of anxiety and antidepressants with pulse rate variability. | Friligkou E et al. | β | 2025 | β |
| Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of 232 complex traits in pigs. | Xu Z et al. | β | 2025 | β |
| Integrating multi-ancestry genomic and proteomic data to identify blood risk biomarkers and target proteins for breast cancer genetic risk loci. | Jia G et al. | β | 2025 | β |
| Integration of transcriptome-wide association study and gene-based association analysis identifies candidate genes for Hodgkin lymphoma. | Jia WH et al. | β | 2025 | β |
| Integrative Approaches Identify Genetic Determinants of Levodopa Induced Dyskinesia. | Wan Y et al. | β | 2025 | β |
| Integrative bioinformatics frameworks for abdominal aortic aneurysm using GWAS meta-analysis, biological network construction, and structural modeling. | Sagulkoo P et al. | β | 2025 | β |
| Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS. | Dong ZY et al. | β | 2025 | β |
| Integrative genome-wide analysis unveils the genetic landscape of gallstone disease and highlights novel loci with therapeutic potential. | Chen H et al. | β | 2025 | β |
| Integrative Genome-wide Association Meta-analysis of Aortic Aneurysm and Dissection Identifies Five Novel Genes. | Du Y et al. | β | 2025 | β |
| Interactions of genes with alcohol consumption affect insulin sensitivity and beta cell function. | Fu Q et al. | β | 2025 | β |
| Interactive effects of genotype with prenatal stress on DNA methylation at birth. | Mulder RH et al. | β | 2025 | β |
| Investigating the causal role of the gut microbiome in Kawasaki disease: mediating effects of immune cells. | Fan Y et al. | β | 2025 | β |
| Investigating the Contribution of Coding Variants in Alcohol Use Disorder Using Whole-Exome Sequencing Across Ancestries. | Wang L et al. | β | 2025 | β |
| Investigating the potential causal link between BPA and ovarian carcinogenesis: a network toxicology and mendelian randomization study on the CTRC/PRDX1/SKP1 pathway. | Shi Z et al. | β | 2025 | β |
| Investigating the shared genetic architecture between obesity and depression: a large-scale genomewide cross-trait analysis. | Yuan L et al. | β | 2025 | β |
| Is sex at birth a biological coin toss? Insights from a longitudinal and GWAS analysis. | Wang S et al. | β | 2025 | β |
| JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation. | Xu L et al. | β | 2025 | β |
| Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants. | Liu H et al. | β | 2025 | β |
| Large-scale exome sequencing identified 18 novel genes for neuroticism in 394,005 UK-based individuals. | Wu XR et al. | β | 2025 | β |
| Large-scale genome-wide analyses of stuttering. | Polikowsky HG et al. | β | 2025 | β |
| Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty. | Mak JKL et al. | β | 2025 | β |
| Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy. | Tadros R et al. | β | 2025 | β |
| Large-scale multi-trait genome-wide analysis for inflammatory bowel disease reveals new insights into its molecular mechanisms and emphasizes the roles of systemic immune regulation. | Zhu Z et al. | β | 2025 | β |
| Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain. | Jajoo A et al. | β | 2025 | β |
| Limited overlap between genetic effects on disease susceptibility and disease survival. | Yang Z et al. | β | 2025 | β |
| Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO. | Puerta R et al. | β | 2025 | β |
| Local ancestry-informed GWAS of warfarin dose requirement in African Americans identifies a CYP2C19 splicing QTL. | Singh A et al. | β | 2025 | β |
| Logica: A likelihood framework for cross-ancestry local genetic correlation estimation using summary statistics. | Gao B et al. | β | 2025 | β |
| <i>APOE</i> Genotype-Stratified Meta-Analysis of Cognitive Decline Reveals Novel Loci for Language and Global Cognitive Function in Older Adults. | Acharya V et al. | β | 2025 | β |
| <i>CR1</i> variants contribute to FSGS susceptibility across multiple populations. | Skitchenko R et al. | β | 2025 | β |
| Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response. | Chen J et al. | β | 2025 | β |
| Mapping the landscape of childhood obesity: genomic insights and socioeconomic status in Indian school-going children. | Nair JM et al. | β | 2025 | β |
| Maternal asthma and newborn DNA methylation. | Pedersen CT et al. | β | 2025 | β |
| Maternal parity modifies the association of birthweight polygenic score with fetal growth. | Wijesiriwardhana P et al. | β | 2025 | β |
| Mendelian randomisation to uncover causal associations between conformation, metabolism, and production as potential exposure to reproduction in German Holstein dairy cattle. | Schwarz L et al. | β | 2025 | β |
| Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity. | Villaplana-Velasco A et al. | β | 2025 | β |
| Merging metabolomics and genomics provides a catalog of genetic factors that influence molecular phenotypes in pigs linking relevant metabolic pathways. | Bovo S et al. | β | 2025 | β |
| Meta-analyses of clozapine, norclozapine levels and their ratio across three genome wide association studies. | Rask SM et al. | β | 2025 | β |
| Meta-analysis of urinary metabolite GWAS studies identifies novel genome-wide significant loci. | Zaki JK et al. | β | 2025 | β |
| Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity. | Mies G et al. | β | 2025 | β |
| Metabolic variation reflects dietary exposure in a multi-ethnic Asian population. | Low DY et al. | β | 2025 | β |
| Metabolomics profiling in multi-ancestral individuals with type 2 diabetes in Singapore identified metabolites associated with renal function decline. | Chen Y et al. | β | 2025 | β |
| metaGE: Investigating genotype x environment interactions through GWAS meta-analysis. | De Walsche A et al. | β | 2025 | β |
| Methods for multiancestry genome-wide association study meta-analysis. | Yap CF et al. | β | 2025 | β |
| Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants. | Hu Y et al. | β | 2025 | β |
| Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomization. | Zhao SS et al. | β | 2025 | β |
| Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration. | Jacques M et al. | β | 2025 | β |
| Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. | Johnson EC et al. | β | 2025 | β |
| Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study. | Kuang A et al. | β | 2025 | β |
| Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids. | Bentley AR et al. | β | 2025 | β |
| Multi-ancestry genome-wide association analyses of polycystic ovary syndrome. | Zhao H et al. | β | 2025 | β |
| Multi-ancestry genome-wide association meta-analysis identifies candidate genes for computed tomography-based carcass composition traits in pigs. | Han H et al. | β | 2025 | β |
| Multi-ancestry genome-wide association meta-analysis identifies novel associations and informs genetic risk prediction for Hirschsprung disease. | Zhong Y et al. | β | 2025 | β |
| Multi-ancestry genome-wide association meta-analysis of buprenorphine treatment response. | Davis CN et al. | β | 2025 | β |
| Multi-ancestry genome-wide association study of topiramate's effects on heavy alcohol use. | Davis CN et al. | β | 2025 | β |
| Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. | Rajabli F et al. | β | 2025 | β |
| Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis. | Zhang M et al. | β | 2025 | β |
| Multi-ancestry investigation of the genomics of erectile dysfunction. | Bright U et al. | β | 2025 | β |
| Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain. | Stanaway IB et al. | β | 2025 | β |
| Multi-ancestry meta-analysis of keloids uncovers novel susceptibility loci in diverse populations. | Greene CA et al. | β | 2025 | β |
| Multi-ancestry sequencing-based genome-wide association study of C-reactive protein in 513,273 genomes. | Li H et al. | β | 2025 | β |
| Multi-ancestry whole genome sequencing analysis of lean body mass. | Zhang X et al. | β | 2025 | β |
| Multimodal analysis stratifies genetic susceptibility and reveals the pathogenic mechanism of kidney injury in diabetic nephropathy. | Jiang S et al. | β | 2025 | β |
| Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores. | O'Neill N et al. | β | 2025 | β |
| Multi-omic insights into mitochondrial dysfunction and prostatic disease: evidence from transcriptomics, proteomics, and methylomics. | Gong B et al. | β | 2025 | β |
| Multi-omics analysis identifies SNP-associated immune-related signatures by integrating Mendelian randomization and machine learning in hepatocellular carcinoma. | Kou Q et al. | β | 2025 | β |
| Multi-omics and Mendelian randomization study explores potential therapeutic targets for meningiomas. | Li Y et al. | β | 2025 | β |
| Multi-omics integration reveals Chr1 associated QTL mediating backfat thickness in pigs. | Yu N et al. | β | 2025 | β |
| Multi-omics integrative analysis reveals novel genetic loci and candidate genes for ischemic stroke. | Wang M et al. | β | 2025 | β |
| Multi-phase, multi-ethnic GWAS uncovers putative loci in predisposition to elite sprint and power performance, health and disease. | Wang G et al. | β | 2025 | β |
| Multiple association studies identify 3 novel candidate genes for teat number trait in Danish Landrace and Large White pigs: BRINP3, LIN52, and UBE3B. | Qiu Z et al. | β | 2025 | β |
| Multitrait genome-wide association best linear unbiased prediction of genetic values. | Meuwissen T et al. | β | 2025 | β |
| Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease. | Geng J et al. | β | 2025 | β |
| Neurogenomic and behavioral principles shape freezing dynamics and synergistic performance in Drosophila melanogaster. | Sato DX et al. | β | 2025 | β |
| Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a vicious cycle. | Jin Y et al. | β | 2025 | β |
| Newborn blood DNA methylation and childhood asthma: findings from the ECHO program. | Li Y et al. | β | 2025 | β |
| New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a fieldΒ trial European network. | Montardit-Tarda F et al. | β | 2025 | β |
| Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese. | Zhou D et al. | β | 2025 | β |
| Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian cohorts. | Santin A et al. | β | 2025 | β |
| Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer. | Simoes AR et al. | β | 2025 | β |
| Novel genetic associations with childhood adipocytokines in Indian adolescents. | Nair JM et al. | β | 2025 | β |
| Novel Genetic Loci for Nontuberculous Mycobacterial Pulmonary Disease and Potential Protective Effect of Body Mass Index. | Park K et al. | β | 2025 | β |
| Novel Genetic Loci in Early-Onset Gout Derived From Whole-Genome Sequencing of an Adolescent Gout Cohort. | Ji A et al. | β | 2025 | β |
| Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD. | Wilson AC et al. | β | 2025 | β |
| Nuanced HEXACO: A Meta-Analysis of HEXACO Cross-Rater Agreement, Heritability, and Rank-Order Stability. | Henry S et al. | β | 2025 | β |
| Optimization of multi-ancestry polygenic risk score disease prediction models. | Lerga-Jaso J et al. | β | 2025 | β |
| Optimized summary-statistic-based single-cell eQTL meta-analysis. | Korshevniuk M et al. | β | 2025 | β |
| Patient stratification by genetic risk in Alzheimer's disease is only effective in the presence of phenotypic heterogeneity. | Euesden J et al. | β | 2025 | β |
| Plasma Circulating Metabolites Associated With Steatotic Liver Disease and Liver Enzymes: A Multiplatform Population-Based Study. | Abozaid YJ et al. | β | 2025 | β |
| Plasma proteomic associations with Alzheimer's disease endophenotypes. | Afshar S et al. | β | 2025 | β |
| Polygenic enrichment analysis in multi-omics levels identifies cell/tissue specific associations with schizophrenia based on single-cell RNA sequencing data. | Cheng B et al. | β | 2025 | β |
| Polygenic risk score prediction accuracy convergence. | Henches L et al. | β | 2025 | β |
| Polygenic score analysis identifies distinct genetic risk profiles in Alzheimer's disease comorbidities. | HernΓ‘ndez CF et al. | β | 2025 | β |
| Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study. | Douville NJ et al. | β | 2025 | β |
| Polygenic scores contribution to Parkinson's disease comorbidities. | HernΓ‘ndez CF et al. | β | 2025 | β |
| Polygenic scores for dizygotic twinning: insights into the genetic architecture of female fertility. | Hubers N et al. | β | 2025 | β |
| Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization. | GΓ‘lvez-Montosa F et al. | β | 2025 | β |
| Potential Causal Relationship Between Chronic Obstructive Pulmonary Disease and Diabetes: A Bidirectional Two-Sample Mendelian Randomization Study. | Wang X et al. | β | 2025 | β |
| Predicting Lung Cancer in Korean Never-Smokers With Polygenic Risk Scores. | Kim J et al. | β | 2025 | β |
| Prenatal organophosphate ester exposure and epigenetic changes at birth: a characterization of the methylome in the ECHO cohort. | Schrott R et al. | β | 2025 | β |
| Prenatal per- and polyfluoroalkyl substance exposures and DNA methylation among newborns in the Environmental influences on Child Health Outcomes program. | Schrott R et al. | β | 2025 | β |
| Prevalence of pendrin defects in sudanese families with congenital hypothyroidism. | Islam MS et al. | β | 2025 | β |
| Prioritizing Parkinson's disease risk genes in genome-wide association loci. | Lange LM et al. | β | 2025 | β |
| Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease. | Caro I et al. | β | 2025 | β |
| Proteome-wide association study of prostate cancer risk across populations. | Zhong H et al. | β | 2025 | β |
| Proteome-wide Mendelian randomization identifies causal plasma proteins in prostate cancer development. | Wu J et al. | β | 2025 | β |
| Proteomic biomarkers of emphysema-predominant and non-emphysema-predominant chronic obstructive pulmonary disease. | Zhang YH et al. | β | 2025 | β |
| Reassessing the link between adiposity and head and neck cancer: a Mendelian randomization study. | Morales Berstein F et al. | β | 2025 | β |
| Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions. | Jia G et al. | β | 2025 | β |
| Revealing the genetic architectures underlying organ-specific aging based on proteomic data. | Zhu RJ et al. | β | 2025 | β |
| rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population. | Park K et al. | β | 2025 | β |
| Schizophrenia is associated with altered DNA methylation variance. | Kiltschewskij DJ et al. | β | 2025 | β |
| Secure and federated quantitative trait loci mapping with privateQTL. | Choi YA et al. | β | 2025 | β |
| Sequence-based genome-wide association study and fine-mapping in German Holstein reveal new quantitative trait loci for health traits. | KriΕΎanac AM et al. | β | 2025 | β |
| Sequence-based GWAS in 180,000 German Holstein cattle reveals new candidate variants for milk production traits. | KriΕΎanac AM et al. | β | 2025 | β |
| Sequence-based GWAS reveals genes and variants associated with predicted methane emissions in French dairy cows. | Fresco S et al. | β | 2025 | β |
| Sex-stratified genome-wide association meta-analysis of major depressive disorder. | Thomas JT et al. | β | 2025 | β |
| Sex-stratified genome-wide meta-analysis identifies novel loci for cognitive decline in older adults. | Acharya V et al. | β | 2025 | β |
| Shared genetic architecture and bidirectional clinical risks within the psycho-metabolic nexus. | Guo X et al. | β | 2025 | β |
| Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses. | Shen J et al. | β | 2025 | β |
| Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits. | Wilson EP et al. | β | 2025 | β |
| SLCO1B1 Functional Variants, Bilirubin, Statin-Induced Myotoxicity, and Recent Sub-Saharan African Ancestry: A Precision Medicine Health Equity Study. | Haldar T et al. | β | 2025 | β |
| Specific plasma lipid species in children are causally associated with kawasaki disease: a mendelian randomization analysis. | Zhen C et al. | β | 2025 | β |
| Striking convergent selection history of wheat and barley and its potential for breeding. | Sow MD et al. | β | 2025 | β |
| Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects. | Wang H et al. | β | 2025 | β |
| Systematic review and meta-analysis of bulk RNAseq studies in human Alzheimer's disease brain tissue. | Aguzzoli Heberle B et al. | β | 2025 | β |
| Targeting specific kinase substrates rescues increased colitis severity induced by the Crohn's disease-linked LRRK2-N2081D variant. | Heaton GR et al. | β | 2025 | β |
| The brief resilience scale: a genome-wide association study in the UK Biobank. | Cornelis MC et al. | β | 2025 | β |
| The candidate gene OLFML2A possibly contributed to the variation of total number of teats in Meishan and Erhualian pigs by influencing the formation of mammary placodes. | Liu CX et al. | β | 2025 | β |
| The causal effects of remnant cholesterol on increased risk of cardiovascular diseases in East Asians. | Lin C et al. | β | 2025 | β |
| The genetic architecture of brainstem structures. | Xue H et al. | β | 2025 | β |
| The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture. | Faber BG et al. | β | 2025 | β |
| The Genetic Architecture of the Human Corpus Callosum and its Subregions. | Bhatt RR et al. | β | 2025 | β |
| The Genetic Associations Between Kidney Stones, Obesity, Type 2 Diabetes, and Hypertension. | Zhou LT et al. | β | 2025 | β |
| The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases. | Konieczny MJ et al. | β | 2025 | β |
| The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation at the NAV3 and UNC5C loci. | Huang J et al. | β | 2025 | β |
| The impact of common and rare genetic variants on bradyarrhythmia development. | Weng LC et al. | β | 2025 | β |
| The Interrelationship between Preconception Folate Nutritional Intake and Child Genetic Liability in the Risk of Childhood Acute Lymphoblastic Leukemia. | Xiang Y et al. | β | 2025 | β |
| The Neurodegenerative Disease Knowledge Portal: Propelling Discovery Through the Sharing of Neurodegenerative Disease Genomic Resources. | Dilliott AA et al. | β | 2025 | β |
| The Non-Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism. | Maiorino T et al. | β | 2025 | β |
| The phenotypic and genetic association between endometriosis and immunological diseases. | Shigesi N et al. | β | 2025 | β |
| TidyGWAS: a scalable approach for standardized cleaning of genome-wide association study summary statistics. | Harder A et al. | β | 2025 | β |
| Towards clinical applicability of fMRI via systematic filtering. | Koten JW et al. | β | 2025 | β |
| Trans-ancestral rare variant association study with machine learning-based phenotyping for metabolic dysfunction-associated steatotic liver disease. | Chen R et al. | β | 2025 | β |
| Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects. | Downie CG et al. | β | 2025 | β |
| Trans-ancestry GWAS identifies 59 loci and improves risk prediction and fine-mapping for kidney stone disease. | Cao X et al. | β | 2025 | β |
| Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer. | Wang L et al. | β | 2025 | β |
| Transcriptome analysis of early- and late-onset Alzheimer's disease in Korean cohorts. | Han SW et al. | β | 2025 | β |
| Transcriptome-wide association study revealed novel causal genes of renal-biopsy proven diabetic nephropathy. | Ma Z et al. | β | 2025 | β |
| Transethnic analysis identifies SORL1 variants and haplotypes protective against Alzheimer's disease. | Zhou X et al. | β | 2025 | β |
| Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations. | Nicolas A et al. | β | 2025 | β |
| Translational genomics of osteoarthritis in 1,962,069 individuals. | Hatzikotoulas K et al. | β | 2025 | β |
| TTN and BAG3 in Cancer Therapy-Related Cardiomyopathy Among Long-Term Survivors of Childhood Cancer. | Neupane A et al. | β | 2025 | β |
| Type 2 Diabetes Polygenic Risk Score Interactions with Lifestyle Risk Factors in Black Americans. | Scadden AW et al. | β | 2025 | β |
| Uncovering causal gene-tissue pairs and variants through a multivariate TWAS controlling for infinitesimal effects. | Yang Y et al. | β | 2025 | β |
| Unraveling the causal impact of smoking and its DNA methylation signatures on cardiovascular disease: Mendelian randomization and colocalization analysis. | Cao S et al. | β | 2025 | β |
| Unraveling the genetic landscape of susceptibility to multiple primary cancers. | Middha P et al. | β | 2025 | β |
| Unraveling the genetics of gulf war illness in diverse participants enrolled in the million veteran program. | Pathak GA et al. | β | 2025 | β |
| Unraveling the genetic susceptibility of irritable bowel syndrome: integrative genome-wide analyses in 845Β 492 individuals: a diagnostic study. | Huang W et al. | β | 2025 | β |
| Unveiling circulating targets in pancreatic cancer: Insights from proteogenomic evidence and clinical cohorts. | Feng H et al. | β | 2025 | β |
| Unveiling CTRB2, RSPO3, KLOTB, and ROR1 as obesity-pancreatic disease association proteins: a comprehensive Mendelian randomization study. | Zhou C et al. | β | 2025 | β |
| Unveiling genetic and biological links: exploring the intersection of autoimmune and psychiatric disorders. | Liwayiding A et al. | β | 2025 | β |
| Using genotype imputation to integrate Canola populations for genome-wide association and genomic prediction of blackleg resistance. | Zhao H et al. | β | 2025 | β |
| Variants in CALD1, ESRP1, and RBFOX1 are associated with orofacial cleft risk. | Carlson JC et al. | β | 2025 | β |
| Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants. | Wang L et al. | β | 2025 | β |
| Whole-genome sequencing analyses suggest novel genetic factors associated with Alzheimer's disease and a cumulative effects model for risk liability. | Kim JP et al. | β | 2025 | β |
| Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. | Zhang X et al. | β | 2025 | β |
| Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene. | Sonehara K et al. | β | 2025 | β |
| X-chromosome association study reveals genetic susceptibility loci of hypospadias in southern Chinese population. | Liu Y et al. | β | 2025 | β |
| X-chromosome-wide association study for Alzheimer's disease. | Le Borgne J et al. | β | 2025 | β |
| 25-Hydroxyvitamin D, Vitamin D Binding Protein and Gestational Diabetes Mellitus: A Two-Sample Mendelian Randomization Study. | Qiu Y et al. | β | 2024 | β |
| Acetate enables metabolic fitness and cognitive performance during sleep disruption. | He Q et al. | β | 2024 | β |
| A compendium of genetic regulatory effects across pig tissues. | Teng J et al. | β | 2024 | β |
| A comprehensive map of the aging blood methylome in humans. | Seale K et al. | β | 2024 | β |
| Adaptive selection at G6PD and disparities in diabetes complications. | Breeyear JH et al. | β | 2024 | β |
| Addressing overlapping sample challenges in genome-wide association studies: Meta-reductive approach. | Rajabli F et al. | β | 2024 | β |
| Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. | Zhao S et al. | β | 2024 | β |
| Advancing crop improvement through GWAS and beyond in mung bean. | Ahmed SR et al. | β | 2024 | β |
| A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels. | de Vries PS et al. | β | 2024 | β |
| A genome-wide association analysis reveals new pathogenic pathways in gout. | Major TJ et al. | β | 2024 | β |
| A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease. | Riesmeijer SA et al. | β | 2024 | β |
| A genome-wide association meta-analysis of all-cause and vascular dementia. | Mega Vascular Cognitive Impairment and Dementia (MEGAVCID) consortium | β | 2024 | β |
| A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits. | Zhu Y et al. | β | 2024 | β |
| A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals. | Ito S et al. | β | 2024 | β |
| A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort. | Chen SP et al. | β | 2024 | β |
| A genome-wide association study of hand eczema identifies locus 20q13.33 and reveals genetic overlap with atopic dermatitis. | Rosenberg FM et al. | β | 2024 | β |
| A genome-wide association study of neonatal metabolites. | He Q et al. | β | 2024 | β |
| A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis. | Constantinescu AE et al. | β | 2024 | β |
| A genome-wide association study of social trust in 33,882 Danish blood donors. | Sequeros CB et al. | β | 2024 | β |
| A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. | Flatby HM et al. | β | 2024 | β |
| A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans. | Moksnes MR et al. | β | 2024 | β |
| A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology. | Gupta P et al. | β | 2024 | β |
| A genome-wide meta-analysis of palmoplantar pustulosis implicates T<sub>H</sub>2 responses and cigarette smoking in disease pathogenesis. | Hernandez-Cordero A et al. | β | 2024 | β |
| A GWAS for grip strength in cohorts of children-Advantages of analysing young participants for this trait. | Abbondanza F et al. | β | 2024 | β |
| A large-scale microRNA transcriptome-wide association study identifies two susceptibility microRNAs, miR-1307-5p and miR-192-3p, for colorectal cancer risk. | Chen Z et al. | β | 2024 | β |
| Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex. | White JD et al. | β | 2024 | β |
| Alcohol Use Disorder Polygenic Score Compared With Family History and ADH1B. | Lai D et al. | β | 2024 | β |
| Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores. | Szczerbinski L et al. | β | 2024 | β |
| A multi-ancestry genetic study of pain intensity in 598,339 veterans. | Toikumo S et al. | β | 2024 | β |
| A multi-ancestry genome-wide association study in type 1 diabetes. | Michalek DA et al. | β | 2024 | β |
| A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer. | Gao G et al. | β | 2024 | β |
| A multi-trait epigenome-wide association study identified DNA methylation signature of inflammation among men with HIV. | Chen J et al. | β | 2024 | β |
| Analysis of rare Parkinson's disease variants in millions of people. | Pitz V et al. | β | 2024 | β |
| Ancestry-independent risk of venous thromboembolism in individuals with sickle cell trait vs factor V Leiden. | Lin KH et al. | β | 2024 | β |
| Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium. | El Sharkawy M et al. | β | 2024 | β |
| A novel GWAS locus influences microvascular response to mental stress and predicts adverse cardiovascular events. | Almuwaqqat Z et al. | β | 2024 | β |
| A novel statistical framework for meta-analysis of total mediation effect with high-dimensional omics mediators in large-scale genomic consortia. | Xu Z et al. | β | 2024 | β |
| A phenome-wide association study of methylated GC-rich repeats identifies a GCC repeat expansion in AFF3 associated with intellectual disability. | Jadhav B et al. | β | 2024 | β |
| A phenome-wide association study of tandem repeat variation in 168,554 individuals from the UK Biobank. | Manigbas CA et al. | β | 2024 | β |
| A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry. | Schwantes-An TH et al. | β | 2024 | β |
| A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation. | Li S et al. | β | 2024 | β |
| Assessing the Role of Cortisol in Anxiety, Major Depression, and Neuroticism: A Mendelian Randomization Study Using <i>SERPINA6</i>/<i>SERPINA1</i> Variants. | Chan II et al. | β | 2024 | β |
| Assessment of circulating proteins in thyroid cancer: Proteome-wide Mendelian randomization and colocalization analysis. | Fan Q et al. | β | 2024 | β |
| Association between biological ageing and periodontitis: Evidence from a cross-sectional survey and multi-omics Mendelian randomization analysis. | Huang Z et al. | β | 2024 | β |
| Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis. | Yarmolinsky J et al. | β | 2024 | β |
| Association between physical frailty and cortical structure in middle-aged and elderly people: a Mendelian randomization study. | Zhang X et al. | β | 2024 | β |
| Association of common genetic variants with chronic axonal polyneuropathy in the general population: a genome-wide association study. | Taams NE et al. | β | 2024 | β |
| Association of genetic variation in <i>COL11A1</i> with adolescent idiopathic scoliosis. | Yu H et al. | β | 2024 | β |
| Association of genetic variation on X chromosome with systemic lupus erythematosus in both Thai and Chinese populations. | Tangtanatakul P et al. | β | 2024 | β |
| Association of oxidative stress and inflammatory metabolites with Alzheimer's disease cerebrospinal fluid biomarkers in mild cognitive impairment. | Ahmad S et al. | β | 2024 | β |
| Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis. | Guillen-Guio B et al. | β | 2024 | β |
| A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. | Ferrell M et al. | β | 2024 | β |
| Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses. | Leblanc FJA et al. | β | 2024 | β |
| Better together against genetic heterogeneity: A sex-combined joint main and interaction analysis of 290 quantitative traits in the UK Biobank. | Lin B et al. | β | 2024 | β |
| Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes. | Yan D et al. | β | 2024 | β |
| Biofortification of Triticum species: a stepping stone to combat malnutrition. | Kumar J et al. | β | 2024 | β |
| Body mass index stratification optimizes polygenic prediction of type 2 diabetes in cross-biobank analyses. | Ojima T et al. | β | 2024 | β |
| Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry. | Burns K et al. | β | 2024 | β |
| Bone health index in the assessment of bone health: The Generation R Study. | Prijatelj V et al. | β | 2024 | β |
| Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics. | Yap CX et al. | β | 2024 | β |
| Causal association between plasma metabolites and diverse autoimmune diseases: a two-sample bidirectional mendelian randomization study. | Yuan X et al. | β | 2024 | β |
| Causal relationship between beta-2 microglobulin and B-cell malignancies: genome-wide meta-analysis and a bidirectional two-sample Mendelian randomization study. | Li J et al. | β | 2024 | β |
| Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults. | Pozarickij A et al. | β | 2024 | β |
| Cellular communities reveal trajectories of brain ageing and Alzheimer's disease. | Green GS et al. | β | 2024 | β |
| Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer's disease in a European population. | Simmonds E et al. | β | 2024 | β |
| Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study. | Wei Z et al. | β | 2024 | β |
| Clinical and genetic risk factors for progressive fibrosis in metabolic dysfunction-associated steatotic liver disease. | Kaplan DE et al. | β | 2024 | β |
| Clinical Application of Polygenic Risk Score in IgA Nephropathy. | Xu L et al. | β | 2024 | β |
| Clinical spectrum of Transthyretin amyloidogenic mutations among diverse population origins. | De Lillo A et al. | β | 2024 | β |
| Combined Genetic Association and Differed Expression Analysis of <i>UBE2L3</i> Uncovers a Genetic Regulatory Role of (Immuno)proteasome in IgA Nephropathy. | Xu LL et al. | β | 2024 | β |
| Common variants increase risk for congenital diaphragmatic hernia within the context of de novo variants. | Qiao L et al. | β | 2024 | β |
| Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome. | Hicks EM et al. | β | 2024 | β |
| Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. | Hoang TT et al. | β | 2024 | β |
| Comprehensive genetic study of the insulin resistance marker TG:HDL-C in the UK Biobank. | Oliveri A et al. | β | 2024 | β |
| Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts. | Zhang X et al. | β | 2024 | β |
| Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder. | Bigdeli TB et al. | β | 2024 | β |
| Critical genes in genitourinary embryogenesis are related to the development of adult hydrocele. | Roberson JL et al. | β | 2024 | β |
| Cross-ancestry analysis of brain QTLs enhances interpretation of schizophrenia genome-wide association studies. | Chen Y et al. | β | 2024 | β |
| Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking. | Johnson EC et al. | β | 2024 | β |
| Cross-Sectional Associations between Prenatal Per- and Poly-Fluoroalkyl Substances and Bioactive Lipids in Three Environmental Influences on Child Health Outcomes (ECHO) Cohorts. | Suthar H et al. | β | 2024 | β |
| CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET. | Nho K et al. | β | 2024 | β |
| Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies. | Tian J et al. | β | 2024 | β |
| Differential effects of environmental exposures on clinically relevant endophenotypes between sexes. | GonzΓ‘lez Zarzar T et al. | β | 2024 | β |
| Directional integration and pathway enrichment analysis for multi-omics data. | Slobodyanyuk M et al. | β | 2024 | β |
| Discovery and prioritization of genetic determinants of kidney function in 297,355 individuals from Taiwan and Japan. | Chen HL et al. | β | 2024 | β |
| Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses. | Bocher O et al. | β | 2024 | β |
| Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. | Verma A et al. | β | 2024 | β |
| DNA methylation and stroke prognosis: an epigenome-wide association study. | JimΓ©nez-Balado J et al. | β | 2024 | β |
| DNA methylation-estimated phenotypes, telomere length and risk of ischemic stroke: epigenetic age acceleration of screening and a Mendelian randomization study. | Maimaiti A et al. | β | 2024 | β |
| DNA methylation risk score for type 2 diabetes is associated with gestational diabetes. | Linares-Pineda TM et al. | β | 2024 | β |
| Does Thrombosis Play a Causal Role in Lacunar Stroke and Cerebral Small Vessel Disease? | Koohi F et al. | β | 2024 | β |
| Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan. | Debban CL et al. | β | 2024 | β |
| Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes. | Alcalde-Herraiz M et al. | β | 2024 | β |
| Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study. | Calzari L et al. | β | 2024 | β |
| Epigenome-wide association study of dietary fatty acid intake. | Lange de Luna J et al. | β | 2024 | β |
| Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain. | Opsahl JO et al. | β | 2024 | β |
| Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts. | Huang BZ et al. | β | 2024 | β |
| Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease. | Lafontaine N et al. | β | 2024 | β |
| Evaluating three strategies of genome-wide association analysis for integrating data from multiple populations. | Zhong Z et al. | β | 2024 | β |
| Examining the role of common variants in rare neurodevelopmental conditions. | Huang QQ et al. | β | 2024 | β |
| Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease. | Petrazzini BO et al. | β | 2024 | β |
| Exome-wide analysis implicates rare protein-altering variants in human handedness. | Schijven D et al. | β | 2024 | β |
| Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function. | Seo J et al. | β | 2024 | β |
| Exploring the complexities of epigenetics in multiple sclerosis: A study involving meta-analysis of DNA methylation profiles, epigenetic drift, and rare epivariations. | Baldrighi GN et al. | β | 2024 | β |
| Exploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts. | GarzΓ³n RodrΓguez N et al. | β | 2024 | β |
| Expression- and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status. | McClellan JC et al. | β | 2024 | β |
| Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry. | Ray NR et al. | β | 2024 | β |
| Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. | Yuan K et al. | β | 2024 | β |
| Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes. | Chen Z et al. | β | 2024 | β |
| Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study. | Friligkou E et al. | β | 2024 | β |
| Gene-environment interactions in human health. | Herrera-Luis E et al. | β | 2024 | β |
| Genetically defined causal effects of natural killer cells related traits in risk of infection: a Mendelian randomization study. | Lin Y et al. | β | 2024 | β |
| Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genes. | Du Z et al. | β | 2024 | β |
| Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity. | Tervi A et al. | β | 2024 | β |
| Genetic architecture and biology of youth-onset type 2 diabetes. | Kwak SH et al. | β | 2024 | β |
| Genetic architecture and socio-environmental risk factors for major depressive disorder in Nepal. | Choi KW et al. | β | 2024 | β |
| Genetic architecture distinguishes tinnitus from hearing loss. | Clifford RE et al. | β | 2024 | β |
| Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people. | Koyanagi YN et al. | β | 2024 | β |
| Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits. | Wang C et al. | β | 2024 | β |
| Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in <i>CD46</i> and other loci. | Grodstein F et al. | β | 2024 | β |
| Genetic Architecture of Neurological Disorders and Their Endophenotypes: Insights from Genetic Association Studies. | Sargurupremraj M | β | 2024 | β |
| Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology. | Madsen AL et al. | β | 2024 | β |
| Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences. | Burren OS et al. | β | 2024 | β |
| Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets. | Gagnon E et al. | β | 2024 | β |
| Genetic association analysis of human median voice pitch identifies a common locus for tonal and non-tonal languages. | Di Y et al. | β | 2024 | β |
| Genetic association of the gut microbiota with epigenetic clocks mediated by inflammatory cytokines: a Mendelian randomization analysis. | Tian S et al. | β | 2024 | β |
| Genetic associations of protein-coding variants in venous thromboembolism. | He XY et al. | β | 2024 | β |
| Genetic associations with dementia-related proteinopathy: Application of item response theory. | Katsumata Y et al. | β | 2024 | β |
| Genetic associations with psychosis and affective disturbance in Alzheimer's disease. | Antonsdottir IM et al. | β | 2024 | β |
| Genetic basis of pregnancy-associated decreased platelet counts and gestational thrombocytopenia. | Yang Z et al. | β | 2024 | β |
| Genetic determinants of obesity in Korean populations: exploring genome-wide associations and polygenic risk scores. | Jo J et al. | β | 2024 | β |
| Genetic drivers and cellular selection of female mosaic X chromosome loss. | Liu A et al. | β | 2024 | β |
| Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. | Suzuki K et al. | β | 2024 | β |
| Genetic drivers of human plasma metabolites that determine mortality in heart failure patients with reduced ejection fraction. | Revathi Venkateswaran V et al. | β | 2024 | β |
| Genetic evidence for serum amyloid PΒ component as a drug target in neurodegenerative disorders. | Schmidt AF et al. | β | 2024 | β |
| Genetic evidence for the causal effects of C-reactive protein on self-reported habitual sleep duration. | Iakunchykova O et al. | β | 2024 | β |
| Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression. | Zhukovsky P et al. | β | 2024 | β |
| Genetic insight into the relationship between inflammatory bowel disease and <i>Clostridioides difficile</i> infection. | Cushing-Damm KC et al. | β | 2024 | β |
| Genetic liability estimated from large-scale family data improves genetic prediction, risk score profiling, and gene mapping for major depression. | Dybdahl Krebs M et al. | β | 2024 | β |
| Genetic risk factors for Mesoamerican nephropathy. | Friedman DJ et al. | β | 2024 | β |
| Genetic risk factors underlying white matter hyperintensities and cortical atrophy. | Patel Y et al. | β | 2024 | β |
| Genetics of sleep medication purchases suggests causality from sleep problems to psychiatric traits. | Broberg M et al. | β | 2024 | β |
| Genetic Susceptibility to Astrovirus Diarrhea in Bangladeshi Infants. | Chen L et al. | β | 2024 | β |
| Genetic Variance in Heparan Sulfation Is Associated With Salt Sensitivity. | Oppelaar JJ et al. | β | 2024 | β |
| Genetic variants affecting mitochondrial function provide further insights for kidney disease. | CaΓ±adas-Garre M et al. | β | 2024 | β |
| Genetic Variants Associated with Sweat Gland Phenotypes in 6210 Han Chinese Individuals. | Chen W et al. | β | 2024 | β |
| Genetic Variants Associated with the Risk of Stroke in Sickle Cell Anemia: Systematic Review and Meta-Analysis. | Kumari A et al. | β | 2024 | β |
| Genetic variants for head size share genes and pathways with cancer. | Knol MJ et al. | β | 2024 | β |
| Genetic variation in circadian regulator gene <i>BMAL1</i> in psychiatric, psychological and cardiometabolic traits: a trans-ancestry UK Biobank study. | Daudali H et al. | β | 2024 | β |
| Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism. | SolΓ©-Navais P et al. | β | 2024 | β |
| Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia. | Manzoni C et al. | β | 2024 | β |
| Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. | Keaton JM et al. | β | 2024 | β |
| Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. | Nievergelt CM et al. | β | 2024 | β |
| Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. | Gorman BR et al. | β | 2024 | β |
| Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. | Jia G et al. | β | 2024 | β |
| Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. | Zheng SL et al. | β | 2024 | β |
| Genome-wide association meta-analysis identifies two novel loci associated with dental caries. | Nogawa S et al. | β | 2024 | β |
| Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer. | Laskar RS et al. | β | 2024 | β |
| Genome-wide association studies for pelvic organ prolapse in the Japanese population. | Matsunami M et al. | β | 2024 | β |
| Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects. | Broberg M et al. | β | 2024 | β |
| Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations. | Thorpe HHA et al. | β | 2024 | β |
| Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies. | Wei Y et al. | β | 2024 | β |
| Genome-wide association studies reveal differences in genetic susceptibility between single events vs. recurrent events of atrial fibrillation and myocardial infarction: the HUNT study. | Hall M et al. | β | 2024 | β |
| Genome wide association study and meta-analysis identified multiple new risk loci for freckles in 4813 Chinese individuals. | Luo S et al. | β | 2024 | β |
| Genome-wide association study and polygenic risk score analysis for schizophrenia in a Korean population. | Lee D et al. | β | 2024 | β |
| Genomeβwide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan. | Yang JS et al. | β | 2024 | β |
| Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus. | Elashi AA et al. | β | 2024 | β |
| Genome-Wide Association Study Identifies Genes for Hair Growth and Patterning are Associated With Pilonidal Disease. | Roberson JL et al. | β | 2024 | β |
| Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever. | Kotliar D et al. | β | 2024 | β |
| Genome-Wide Association Study Identifies Pharmacogenomic Variants Associated With Metformin Glycemic Response in African American Patients With Type 2 Diabetes. | Wu B et al. | β | 2024 | β |
| Genome-wide association study implicates lipid pathway dysfunction in antipsychotic-induced weight gain: multi-ancestry validation. | Liao Y et al. | β | 2024 | β |
| Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population. | Park K et al. | β | 2024 | β |
| Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration. | Ahmad S et al. | β | 2024 | β |
| Genome-wide association study of hospitalized patients and acute kidney injury. | Siew ED et al. | β | 2024 | β |
| Genome-wide association study of maternal plasma metabolites during pregnancy. | Liu S et al. | β | 2024 | β |
| Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. | Yonezawa Y et al. | β | 2024 | β |
| Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population. | Strom NI et al. | β | 2024 | β |
| Genome-wide Association Study of Susceptibility to Respiratory Syncytial Virus Hospitalization in Young Children <5 Years of age. | Egeskov-Cavling AM et al. | β | 2024 | β |
| Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations. | Gelernter J et al. | β | 2024 | β |
| Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits. | Kang J et al. | β | 2024 | β |
| Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience. | Jurgens SJ et al. | β | 2024 | β |
| Genome-wide characterization of circulating metabolic biomarkers. | Karjalainen MK et al. | β | 2024 | β |
| Genome-wide determinants of mortality and motor progression in Parkinson's disease. | Tan MMX et al. | β | 2024 | β |
| Genome-wide DNA methylation analysis of cannabis use disorder in a veteran cohort enriched for posttraumatic stress disorder. | Garrett ME et al. | β | 2024 | β |
| Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125β393 Participants. | Young WJ et al. | β | 2024 | β |
| Genome-wide investigation of exogenous female hormones, genetic variation, and venous thromboembolism risk. | Hasser EK et al. | β | 2024 | β |
| Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis. | Sysojev AΓ et al. | β | 2024 | β |
| Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction. | Schormair B et al. | β | 2024 | β |
| Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma. | Diaz-Torres S et al. | β | 2024 | β |
| Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease. | Ge YJ et al. | β | 2024 | β |
| Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction. | Braun A et al. | β | 2024 | β |
| Genome-wide study identifies novel genes associated with bone toxicities in children with acute lymphoblastic leukaemia. | Zhu Q et al. | β | 2024 | β |
| Genome-wide transcriptome analysis of AΞ² deposition on PET in a Korean cohort. | Park T et al. | β | 2024 | β |
| Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome. | AkΓ§imen F et al. | β | 2024 | β |
| Germline genetic regulation of the colorectal tumor immune microenvironment. | Schmit SL et al. | β | 2024 | β |
| Green space exposure and blood DNA methylation at birth and in childhood - A multi-cohort study. | Aguilar-LacasaΓ±a S et al. | β | 2024 | β |
| Gut microbial and human genetic signatures of inflammatory bowel disease increase risk of comorbid mental disorders. | Lee J et al. | β | 2024 | β |
| GWAS Meta-analysis of Kidney Function Traits in Japanese Populations. | Hishida A et al. | β | 2024 | β |
| GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. | Shade LMP et al. | β | 2024 | β |
| Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa. | Janivara R et al. | β | 2024 | β |
| High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene. | Rahimov F et al. | β | 2024 | β |
| HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis. | Peris Sempere V et al. | β | 2024 | β |
| Host genetic regulation of human gut microbial structural variation. | Zhernakova DV et al. | β | 2024 | β |
| Human Leukocyte Antigen Signatures as Pathophysiological Discriminants of Microscopic Colitis Subtypes. | Zheng T et al. | β | 2024 | β |
| Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children. | Ambalavanan A et al. | β | 2024 | β |
| Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags. | Tanigawa Y et al. | β | 2024 | β |
| Identification and characterization of human GDF15 knockouts. | Gurtan AM et al. | β | 2024 | β |
| Identification and validation of supervariants reveal novel loci associated with human white matter microstructure. | Wang S et al. | β | 2024 | β |
| Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts. | Lyu J et al. | β | 2024 | β |
| Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders. | Tesfaye M et al. | β | 2024 | β |
| Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations. | Liu S et al. | β | 2024 | β |
| Identification of risk loci for postpartum depression in a genome-wide association study. | Li X et al. | β | 2024 | β |
| Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis. | Li M et al. | β | 2024 | β |
| Identification of Sweetness Preference-Related Single-Nucleotide Polymorphisms for Polygenic Risk Scores Associated with Obesity. | Bae JH et al. | β | 2024 | β |
| Identification of the VLDLR locus associated with giant cell arteritis and the possible causal role of low-density lipoprotein cholesterol in its pathogenesis. | Iwasaki T et al. | β | 2024 | β |
| Identifying Common Genetic Etiologies Between Inflammatory Bowel Disease and Related Immune-Mediated Diseases. | Liu X et al. | β | 2024 | β |
| Identifying key genes in COPD risk via multiple population data integration and gene prioritization. | Zainab A et al. | β | 2024 | β |
| Impact of COVID-19, lockdowns and vaccination on immune responses in a HIV cohort in the Netherlands. | Otten T et al. | β | 2024 | β |
| Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis. | Dashti HS et al. | β | 2024 | β |
| Insights from immunomics and metabolomics on the associations between prostatic diseases and coronavirus disease 2019. | Yang F et al. | β | 2024 | β |
| Integrated Germline and Somatic Features Reveal Divergent Immune Pathways Driving Response to Immune Checkpoint Blockade. | Sears TJ et al. | β | 2024 | β |
| Integrating GWAS and transcriptomics to identify candidate genes conferring relative growth rate trait in white-feathered broiler. | Liu P et al. | β | 2024 | β |
| Integrating multi-layered biological priors to improve genomic prediction accuracy in beef cattle. | Zhao Z et al. | β | 2024 | β |
| Integrating muti-omics data to identify tissue-specific DNA methylation biomarkers for cancer risk. | Yang Y et al. | β | 2024 | β |
| Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment. | Xin J et al. | β | 2024 | β |
| Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis. | Ghouse J et al. | β | 2024 | β |
| Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation. | ThΓ©riault S et al. | β | 2024 | β |
| Investigating the Epigenetic Landscape of Major Depressive Disorder: A Genome-Wide Meta-Analysis of DNA Methylation Data, Including New Insights into Stochastic Epigenetic Mutations and Epivariations. | Baldrighi GN et al. | β | 2024 | β |
| Investigating the Protective Role of the Mitochondrial 2158βTβ>βC Variant in Parkinson's Disease. | AkΓ§imen F et al. | β | 2024 | β |
| Investigating the Shared Genetic Etiology Between Parkinson's Disease and Depression. | Reyes-PΓ©rez P et al. | β | 2024 | β |
| Investigation of the genetic aetiology of Lewy body diseases with and without dementia. | Wu LY et al. | β | 2024 | β |
| Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection. | Marchal A et al. | β | 2024 | β |
| Large-scale cross-ancestry genome-wide meta-analysis of serum urate. | Cho C et al. | β | 2024 | β |
| Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits. | Broadaway KA et al. | β | 2024 | β |
| Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals. | Romero Villela PN et al. | β | 2024 | β |
| Longitudinal analysis of epigenome-wide DNA methylation reveals novel loci associated with BMI change in East Asians. | Li W et al. | β | 2024 | β |
| Longitudinal Analysis of Sweet Taste Preference Through Genetic and Phenotypic Data Integration. | Bae JH et al. | β | 2024 | β |
| Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers. | Zeng H et al. | β | 2024 | β |
| Low-frequency variants in genes involved in glutamic acid metabolism and Ξ³-glutamyl cycle and risk of coronary artery disease in type 2 diabetes. | Giuffrida FMA et al. | β | 2024 | β |
| Machine learning reveals heterogeneous associations between environmental factors and cardiometabolic diseases across polygenic risk scores. | Naito T et al. | β | 2024 | β |
| Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color. | Kim B et al. | β | 2024 | β |
| Mendelian randomization study of the relationship between blood and urine biomarkers and schizophrenia in the UK Biobank cohort. | Cheng B et al. | β | 2024 | β |
| MESuSiE enables scalable and powerful multi-ancestry fine-mapping of causal variants in genome-wide association studies. | Gao B et al. | β | 2024 | β |
| Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus. | Mathey CM et al. | β | 2024 | β |
| Meta-analysis of Epstein-Barr virus genomes in Southern Chinese identifies genetic variants and high risk viral lineage associated with nasopharyngeal carcinoma. | Wong KW et al. | β | 2024 | β |
| Meta-analysis of genome-wide association studies for cancer therapy-related cardiovascular dysfunction and functional mapping highlight an intergenic region close to TP63. | MartΓnez-Campelo L et al. | β | 2024 | β |
| Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry. | Asiimwe IG et al. | β | 2024 | β |
| Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias. | Weng LC et al. | β | 2024 | β |
| Meta-analysis of six dairy cattle breeds reveals biologically relevant candidate genes for mastitis resistance. | Cai Z et al. | β | 2024 | β |
| metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia. | Rodriguez-Hernandez Z et al. | β | 2024 | β |
| Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations. | Lundin JI et al. | β | 2024 | β |
| Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. | Purdue MP et al. | β | 2024 | β |
| Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference. | Meng X et al. | β | 2024 | β |
| Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk. | Gorman BR et al. | β | 2024 | β |
| Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. | Toikumo S et al. | β | 2024 | β |
| Multiomic integration analysis identifies atherogenic metabolites mediating between novel immune genes and cardiovascular risk. | Carreras-Torres R et al. | β | 2024 | β |
| Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance. | Mei H et al. | β | 2024 | β |
| Multi-omics insight into the metabolic and cellular characteristics in the pathogenesis of hypothyroidism. | Zheng S et al. | β | 2024 | β |
| Multivariate genomic analysis of 5βmillion people elucidates the genetic architecture of shared components of the metabolic syndrome. | Park S et al. | β | 2024 | β |
| NetActivity enhances transcriptional signals by combining gene expression into robust gene set activity scores through interpretable autoencoders. | Ruiz-Arenas C et al. | β | 2024 | β |
| Neurogenetic and multi-omic sources of overlap among sensation seeking, alcohol consumption, and alcohol use disorder. | Miller AP et al. | β | 2024 | β |
| New insights into the genetic loci related to egg weight and age at first egg traits in broiler breeder. | Ma X et al. | β | 2024 | β |
| Nightmares share genetic risk factors with sleep and psychiatric traits. | Ollila HM et al. | β | 2024 | β |
| Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia. | Ochs-Balcom HM et al. | β | 2024 | β |
| Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans. | Akinyemi RO et al. | β | 2024 | β |
| Novel genetic insight for psoriasis: integrative genome-wide analyses in 863Β 080 individuals and proteome-wide Mendelian randomization. | Liu S et al. | β | 2024 | β |
| Novel genetic loci of inhibitory control in ADHD and healthy children and genetic correlations with ADHD. | Pang T et al. | β | 2024 | β |
| Novel insights into causal effects of serum lipids and lipid-modifying targets on cholelithiasis. | Chen L et al. | β | 2024 | β |
| Novel risk loci for COVID-19 hospitalization among admixed American populations. | Diz-de Almeida S et al. | β | 2024 | β |
| Nuclear and mitochondrial genetic variants associated with mitochondrial DNA copy number. | Koller A et al. | β | 2024 | β |
| Omics approaches in asthma research: Challenges and opportunities. | Yue M et al. | β | 2024 | β |
| Optimizing and benchmarking polygenic risk scores with GWAS summary statistics. | Zhao Z et al. | β | 2024 | β |
| Pervasive biases in proxy genome-wide association studies based on parental history of Alzheimer's disease. | Wu Y et al. | β | 2024 | β |
| Phenotypic and genetic characteristics of retinal vascular parameters and their association with diseases. | OrtΓn Vela S et al. | β | 2024 | β |
| Pleiotropic Associations with Alzheimer's Disease and Physical Activity: Sex Differences and the Effects of Environment. | Loika Y et al. | β | 2024 | β |
| Polygenic Risk Score Assessment for Coronary Artery Disease in Asian Indians. | Rout M et al. | β | 2024 | β |
| Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study. | Mandla R et al. | β | 2024 | β |
| Population-specific putative causal variants shape quantitative traits. | Koyama S et al. | β | 2024 | β |
| Potential drug targets for osteoporosis identified: A Mendelian randomization study. | Zhao G et al. | β | 2024 | β |
| Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease. | Long H et al. | β | 2024 | β |
| Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank. | Elmore AR et al. | β | 2024 | β |
| Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans. | Tahir UA et al. | β | 2024 | β |
| Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease. | Western D et al. | β | 2024 | β |
| Proteogenomic network analysis reveals dysregulated mechanisms and potential mediators in Parkinson's disease. | Doostparast Torshizi A et al. | β | 2024 | β |
| Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. | Wang L et al. | β | 2024 | β |
| Protocol for genome-wide association study of human blood metabolites. | Iwasaki T et al. | β | 2024 | β |
| Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing. | Sadeghi-Alavijeh O et al. | β | 2024 | β |
| Rare MED12L Variants Are Associated with Susceptibility to Guttate Psoriasis in the Han Chinese Population. | Wu K et al. | β | 2024 | β |
| Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes. | Huerta-Chagoya A et al. | β | 2024 | β |
| Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study. | Rossi N et al. | β | 2024 | β |
| Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders. | Hwang HM et al. | β | 2024 | β |
| Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma. | Alpen K et al. | β | 2024 | β |
| Regulatory elements in <i>SEM1-DLX5-DLX6</i> (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits. | Nicoletti P et al. | β | 2024 | β |
| Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses. | Larsson SC et al. | β | 2024 | β |
| Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory. | Ohseto H et al. | β | 2024 | β |
| Rome III Criteria Capture Higher Irritable Bowel Syndrome SNP-Heritability and Highlight a Novel Genetic Link With Cardiovascular Traits. | Camargo Tavares L et al. | β | 2024 | β |
| Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis. | Bang S et al. | β | 2024 | β |
| SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi-omics research and cohort validation. | Wang S et al. | β | 2024 | β |
| SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease. | Strausz S et al. | β | 2024 | β |
| SEAD reference panel with 22,134 haplotypes boosts rare variant imputation and genome-wide association analysis in Asian populations. | Yang MY et al. | β | 2024 | β |
| Selection scan in Native Americans of Mexico identifies <i>FADS2</i> rs174616: Evidence of gene-diet interactions affecting lipid levels and Delta-6-desaturase activity. | Romero-Hidalgo S et al. | β | 2024 | β |
| Sex-biased genetic regulation of inflammatory proteins in the Dutch population. | Boahen CK et al. | β | 2024 | β |
| Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis. | Czamara D et al. | β | 2024 | β |
| Sex differences in shared genetic determinants between severe mental disorders and metabolic traits. | Pisanu C et al. | β | 2024 | β |
| Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease. | Nordeidet AN et al. | β | 2024 | β |
| Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis. | Liu X et al. | β | 2024 | β |
| Shared genetic architectures of educational attainment in East Asian and European populations. | Chen TT et al. | β | 2024 | β |
| Shared genetics and causal association between plasma levels of SARS-CoV-2 entry receptor ACE2 and Alzheimer's disease. | Zhang Y et al. | β | 2024 | β |
| Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease. | Lee SHT et al. | β | 2024 | β |
| Stratified analyses refine association between TLR7 rare variants and severe COVID-19. | Boos J et al. | β | 2024 | β |
| Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population. | Vanneste M et al. | β | 2024 | β |
| Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. | Daskalakis NP et al. | β | 2024 | β |
| The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome. | Xicota L et al. | β | 2024 | β |
| The genetic architecture of age at menarche and its causal effects on other traits. | Feng GJ et al. | β | 2024 | β |
| The genetic architecture of dog ownership: large-scale genome-wide association study in 97,552 European-ancestry individuals. | Gong T et al. | β | 2024 | β |
| The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders. | Chen SD et al. | β | 2024 | β |
| The genetic architecture of youth anxiety: a study protocol. | McAusland L et al. | β | 2024 | β |
| The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria. | Ojewunmi OO et al. | β | 2024 | β |
| The genetic landscape of neuro-related proteins in human plasma. | Repetto L et al. | β | 2024 | β |
| The goldmine of GWAS summary statistics: a systematic review of methods and tools. | Kontou PI et al. | β | 2024 | β |
| The potential and translational application of infant genetic research. | Ronald A et al. | β | 2024 | β |
| The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study. | Liu J et al. | β | 2024 | β |
| The role of genetically predicted serum iron levels on neurodegenerative and cardiovascular traits. | Belbellaj W et al. | β | 2024 | β |
| Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes. | Kwak SH et al. | β | 2024 | β |
| Translational toxicoepigenetic Meta-Analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead exposure in mouse and human offspring. | Petroff RL et al. | β | 2024 | β |
| Uncovering genetic loci and biological pathways associated with age-related cataracts through GWAS meta-analysis. | Diaz-Torres S et al. | β | 2024 | β |
| Uncovering novel regulatory variants in carbohydrate metabolism: a comprehensive multi-omics study of glycemic traits in the Indian population. | Nair JM et al. | β | 2024 | β |
| Understanding the genetic complexity of puberty timing across the allele frequency spectrum. | Kentistou KA et al. | β | 2024 | β |
| Unraveling interindividual variation of trimethylamine <i>N</i>-oxide and its precursors at the population level. | Andreu-SΓ‘nchez S et al. | β | 2024 | β |
| Unsupervised deep representation learning enables phenotype discovery for genetic association studies of brain imaging. | Patel K et al. | β | 2024 | β |
| Unveiling the Mechanism of Retinoic Acid Therapy for Cutaneous Warts: Insights from Multi-Omics Integration. | Dong ZY et al. | β | 2024 | β |
| Urinary concentrations of phthalate and phthalate alternative metabolites and sperm DNA methylation: A multi-cohort and meta-analysis of men in preconception studies. | Nowak K et al. | β | 2024 | β |
| Using expression data to fine map QTL associated with fertility in dairy cattle. | van den Berg I et al. | β | 2024 | β |
| Valid inference for machine learning-assisted genome-wide association studies. | Miao J et al. | β | 2024 | β |
| Vitamin B<sub>12</sub> protects necrosis of acinar cells in pancreatic tissues with acute pancreatitis. | Chen Y et al. | β | 2024 | β |
| Whole-exome and whole-genome sequencing of 1064 individuals with type 1 diabetes reveals novel genes for diabetic kidney disease. | Haukka JK et al. | β | 2024 | β |
| Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes. | Antikainen AA et al. | β | 2024 | β |
| Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease. | Kang M et al. | β | 2024 | β |
| X-linked genetic associations in sporadic thoracic aortic dissection. | Musfee FI et al. | β | 2024 | β |
| Examining interactions between polygenic scores and interpersonal trauma exposure on alcohol consumption and use disorder in an ancestrally diverse college cohort. | Sheerin CM et al. | β | 2023 | β |