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Chunk #15 — Results — Multivariate regression analyses using CTQ subtypes

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Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders.
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No significant result was observed when studying physical neglect, physical abuse and emotional abuse. We found an interaction between emotional neglect and ‘SS’ genotype on the AAO (p = 0.009) with a trend for an interaction also between emotional neglect and ‘LS’ genotype on the AAO (p = 0.09) in the same model (see Table 2). We found an association between sexual abuse on the AAO (p = 0.02) with no interaction between this subtype of trauma and genotypes (data not shown).