Chunk #14 — Results — Multivariate regression analyses using CTQ subtypes

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Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders.

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Since not all subtypes of trauma are supposed to have equal effects on the AAO with emotional and sexual trauma having possibly a preferential effect13, we tested the following model AAO transformed ~ Genotypes(LLvsLSvsSS) + CTQ subtype + Genotypes × CTQ subtype for each trauma subtype. Transformed AAO (1/sqrt(AAO)) fulfilled the normality assumption (Shapiro-Wilk W = 0.24; p > 0.05).