We then considered the effect of the absence/presence of any trauma sub-type (regardless of the subtype considered) on the AAO according to genotypes. AAO decreased in the presence of trauma (one or two and more trauma subtype(s)) in the ‘SS’ subgroup (Wilcoxon rank test: p = 0.001) and to a lesser extend in the ‘LS’ subgroup (p = 0.04) but not in the ‘LL’ subgroup (p = 0.44) (see Fig. 1 for details).
