The AAO and the CTQ total score were negatively correlated for the whole sample of patients (rho = − 0.16 p = 0.004). However, this correlation was mainly due to patients carrying the ‘SS’ genotype (rho’SS’ = − 0.32 p = 0.002) and the ‘LS’ genotype (rho’LS’ = − 0.17 p = 0.03) with no correlation observed for those patients carrying the ‘LL’ genotype (rho’LL’ = − 0.02 p = 0.88).