Three-dimensional facial imaging used to detect the effects of prenatal alcohol exposure. Each case shows face and philtrum (ridge under nose) shape as well as heat maps indicating significant regions of difference from age- and sex-matched control subjects. The control case shows an unexposed individual with some flattening across the nasal bridge, a small jaw and a strongly grooved philtrum. The heavily exposed (HE) case is an individual with known exposure without clinically recognized fetal alcohol syndrome (FAS). The overall face size is average or larger and the upper part of philtrum is smooth. The FAS case shows a reduced face size and philtrum smoothness, best revealed in the philtrum heat map; red at outer canthi (outer edge of eye) identifies narrow palpebral fissures.
