g:GOSt is the core tool for performing functional enrichment analysis on input gene list. It maps a user provided list of genes to known functional information sources and detects statistically significantly enriched biological processes, pathways, regulatory motifs and protein complexes. Main source of information about genes, identifier types and GO terms and associations is the Ensembl database (17). The Gene Ontology is the most comprehensive resource in g:GOSt covering 467 species and strains represented in Ensembl Genomes and fungi, plants or metazoa specific versions of Ensembl (17), and parasite specific data from WormBase (18).