Baclofen (R-(+)-β-(aminomethyl)-4-chlorobenzenepropanoic acid hydrochloride), adenosine, CGP54626, kynurenic acid, and picrotoxin were purchased from Sigma-Aldrich (St. Louis, MO). (R)-(+)-8-OH-DPAT hydrobromide and WAY100635 maleate were purchased from Tocris (Bristol, UK). ML297 was synthesized in the Vanderbilt Center for Neuroscience Drug Discovery.
