Altogether, this study included 6,142 T2D cases and 7,403 controls (European American (533/1,006), African American (1,077/1,469), Latino (2,220/2,184), Japanese American (1,736/1,761) and Native Hawaiian (576/983)). Genotyping was conducted by the TaqMan allelic discrimination assay (Applied Biosystems, Foster City, CA) [30]. For all SNPs, genotype call rates were >95% among case and control groups in each population and HWE p-values among controls were >0.05 in at least 4 of the 5 ethnic groups and none of the values were <0.01 (Table S6). Subjects missing data for >5 SNPs (n = 82) were removed from the analysis.