The resulting PRS explains ~3% of the variance in predicting PTSD onset (Nagelkerke R2 of 2.96%, p = 0.0175). The corresponding AUC and C-index are 0.57 for both. For stratification, odds ratio for PTSD diagnosis between the highest and lowest quartiles is 4.5 (95% CI = −4.4–60.8), and between highest and lowest deciles is 12.6 (95% CI = 3.9–40.9). The difference in mean CAPS between the highest and lowest quartiles is 28.2 (95% CI = −4.4–60.8), and between the highest and lowest deciles is 53.6 (95% CI = 12.3–94.98).
