From January 1994 through June of 2010, 1,148 persons agreed to annual detailed clinical evaluation and brain donation at the time of death. Of these, 1,139 have completed their baseline clinical evaluation: 68.9% were women; 88.0% were white, non-Hispanic; their mean age was 75.6 years; and mean education was 18.1 years. There were 287 cases of incident dementia and 273 cases of incident Alzheimer’s disease with or without a coexisting condition. Details of the clinical and pathologic methods have been previously reported 17.
