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Chunk #15 — Results — GWAS of PTSD

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Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders.
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No individual loci met the genome-wide significance criteria (p < 5 × 10−8) in the meta-analysis of PTSD (Supplementary Fig. 1). The 10 top SNPs, representing five independent loci, are listed in Supplementary Table 6. The lead SNP for each locus included: Follistatin Like 4 (FSTL4) upstream variant SNP rs2457174, located on chromosome 5 (p = 2.9 × 10−7), intronic Fibronectin Type III And Spry Domain Containing 1 Like (FSD1L) SNP rs9969773 on chromosome 9 (p = 4.0 × 10−7), Cillia And Flagella Associated Protein 54 (CFAP54) downstream variant SNP rs71439002 on chromosome 12 (p = 9.8 × 10−7), intergenic chromosome 4 SNP rs7668166 (p = 1.1 × 10−6), and intergenic chromosome 5 SNP rs67697853 (p = 1.4 × 10−6).