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Chunk #24 — Methods

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Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics.
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The biological correspondence of down-sampled univariate or multivariate GWAS can be evaluated by comparing the results from the Multi-marker analysis of genomic annotation (MAGMA) gene-property analyses in the SNP2GENE function of Functional Mapping and Annotation of Genome-Wide Association Studies (FUMA; Watanabe et al. 2017); version 1.5.0e) software using Spearman rank correlations of point estimates.