Chunk #4 — Introduction

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Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum.

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The aim of the present study was to investigate differential gene expression associated with AUD status in the ventral and dorsal striatum, relate these to GWAS findings, and to integrate the findings with DNA-methylation data using a network approach (WGCNA) in order to identify functionally relevant molecular mechanisms in AUD.