activity and enhance processing of extrinsic task-based stimuli. This latter view derives from the cognitive enhancing effects observed in nicotine-naïve populations (Heishman et al., 2010) as well as evidence that nicotine suppresses the DMN activity in non-smokers (Tanabe et al., 2011). Accordingly, a shift away from an insula-DMN biased pattern of rsFC and towards an insula-ECN pattern may be observed in both smokers and non-smokers, accompanied by enhanced attentional performance.
