In New Zealand, participants were derived from the Dunedin Longitudinal Study [31] (N = 1037, assessed 14 times from birth to age 45 years). We tested nine phenotypes and found significant associations with the BroadABC-based PRS for two: childhood ASB and official-records of juvenile convictions. Although not surviving Bonferroni adjustment, we found nominal significant (p < 0.05) association with the BroadABC-based PRS for eight phenotypes. We did not find evidence for a PRS association with partner violence. Lastly, we compared individuals grouped into the following four distinct developmental trajectories of ASB using general growth mixture modeling: low ASB across childhood through adulthood, childhood-limited ASB, adolescent-onset ASB, and life-course persistent (LCP) ASB [32]. Individuals following the LCP antisocial trajectory were characterized by the highest levels of genetic risk (see Supplementary Fig. 2); the nominally significant higher PRS of the LCP trajectory group compared to the low ASB group (p = 0.032 and p = 0.049, for p value thresholds 0.05 and 0.1 respectively) did not survive Bonferroni adjustment. For a full report of the findings in the Dunedin cohort, see Supplementary Table 9 and Supplementary Note 8.
