Data are from the COGA study, which has been described in detail elsewhere (Begleiter et al., 1999; Nurnberger and Wiegand, 2011). To date, COGA has assessed data on alcohol use frequency, AUD symptom counts, and diagnoses for approximately 17,762 individuals belonging to 2,255 families. COGA’s sample is well-suited for undertaking a systematic comparison of FH measures as its multiplex family data allows for use of the same subjects’ familial information to compute and compare the utility of the two types of FH measures. Also, given that the sample size is large and ethnically diverse, a systematic comparison of the FH measures across gender and race/ethnicity is feasible.
