as determined by ChIP-seq regardless of cell type, mammalian organism or microarray platform. We then find the ranks of the perturbed TFs for each enrichment analysis scoring methods and plot their cumulative distributions. Our results demonstrate that the combined score and the Z-score methods recover more of the ‘correct’ terms compared with the other methods we tested (Figure 1A). This result is consistent with our results from 2013, presented in the original Enrichr publication.
