Chunk #40 — Main Text — The Contribution of Rare Variants to Disease Risk

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The genetics of major depression.

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yes

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spectrum 520Pittsburgh families811,24251.63SADS-LD1S16092.7chr1:243,965,857-244,166,112–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD2S4272.77chr2:232,106,263-232,306,614–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD5S15033.32chr5:98,071,660-98,272,056–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD5S15053.74chr5:119,001,596-119,201,988–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD8S14771.74chr8:31,966,957-32,167,504–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD10S12213.01chr10:57,429,886-57,630,151–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD10S24702.61chr10:92,264,596-92,464,872–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD11S19844.2chr11:1,466,686-1,667,029–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD11S20022.1chr11:79,865,382-80,065,662–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD15S10121.96chr15:38,907,527-39,107,917–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD18S8582.93chr18:54796986-54997312–RMD 375 pairs; MD 520 pairs; mood disorder 610 pairs; depression spectrum 520Pittsburgh families811,24251.63SADS-LD19S5862.49chr19:9,704,793-9,905,143–Abkevich et al., 2003RMD 784; MD 161; BPD 162Utah families1101,35768.98BPSD12S16006chr12:99,200,748-99,401,155MaleCamp et al., 2005RMD 1,513; anxiety 1,141, of which only 718 usedUtah families87NANA–D3S17523.81chr3:97,645,283-97,845,588–RMD 1,513; anxiety 1,141, of which only 718 usedUtah families87NANA–D7S5172.89chr7:4,397,915-4,598,292–RMD 1,513; anxiety 1,141, of which only 718 usedUtah families87NANA–D18S12703.75chr18:61,292,502-61,492,816–RMD 1,513; anxiety 1,141, of which only 718 usedUtah families87NANA–D15S5152.88chr15:43,497,354-43,697,543MaleRMD 1,513; anxiety 1,141, of which only