Chunk #54 — Methods — PAU PRS in independent samples.

Source

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.

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We calculated PAU PRS in three independent samples, where we tested the association between PAU PRS and AD, corrected for age, sex, and 10 PCs. Ten p-value thresholds were applied in all samples.