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Chunk #42 — 4. Discussion

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Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.
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compared to the other regions may make it more vulnerable to ethanol. Another potential contributor to the difference among the regions is the different technology used to analyze those regions; the RNA sequencing used here may be more sensitive to changes. Technical differences cannot, however, be the primary reason because additional regions also examined by RNA sequencing showed many fewer alterations than the DRN (unpublished data).