The Norwegian Thematically Organized Psychosis (TOP) cohort was used for PGS analyses,41 including 2181 European participants (1,060 females, age: 33.1±11.8 years, nBIP=440, nSCZ=697, and ncontrols=1044). We also obtained information on recent cannabis use within 2 years prior to recruitment, and psychotic experience. Details are presented in the Supplementary Methods and Supplementary Table 1. All participants provided written informed consent and the study was approved by The Regional Committee for Medical and Health Research Ethics of South-East Norway.