The present findings demonstrated that temporal dipole activities possess stronger P300 activity compared with frontal dipoles in all groups, which is consistent with the target scalp P300 trait of parietal advantage. The primary interest of the present study was to determine whether the advantage of temporal dipole over frontal dipole could be used to differentiate between anxiety disorder and depressive disorder patients. Because the anxiety disorder patients displayed the strongest temporal advantage, enhanced activity in temporal dipole was compared with the frontal dipole, which suggested that these patients might attempt to enhance posterior dipole activity during target discrimination processing to compensate for deficits in frontal cortex processing.
