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Chunk #38 — Discussion

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Dipole source analysis of auditory P300 response in depressive and anxiety disorders.
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Patients with depressive disorder displayed the weakest temporal advantage among all three groups. Dominating reduction of temporal activity pronounced in right hemisphere suggested a right-hemispheric temporal cortex hypofunction, as well as a right-hemispheric inferior prefrontal cortex hypofunction, which may represent impaired arousal and vigilance mechanisms in depression.