canSAR contains curated and uniformly assessed protein-protein interaction data that we compile from key interactome databases including the IMEx consortium (14), Phosphosite (15), DePOD (16), HuRI (17), Reactome pathways (18), Tfacts (19), TRRUST (20) and MSigDB (21) as well as key publications (e.g. 22–24). Moreover, we curate protein–protein interactions from the PDB and uniquely identify druggable protein–protein interactions interfaces (see below). In the latest version of canSAR, we have curated >990 000 protein–protein interactions for 18,680 human proteins in Swiss-Prot.
