Examination of the chromosomal location of the genes that were significantly different between the ethanol and water groups in the CeA indicated that 75 genes were located within rat ethanol preference QTLs (see Supplemental Table D), and 4 genes (Capzb, Prdm2, Nmnat1, Panx3) that were located within both mouse and rat ethanol QTLs. Capzb is listed in two important GO BP categories (Table 2), i.e., ‘cell projection morphogenesis-neurite development’ and ‘cytoskeletal organization and biogenesis’. Both Capzb and Prdm2 are found in the general BP category of ‘biological regulation’. The highest number of genes that differed between the ethanol and water group in the CeA occurred in rat QTL Alc4 on chromosome 5 (21 genes) and QTL Alc17 on chromosome 6 (18 genes). Among the genes located within a rat ethanol preference QTL, only Usp18 was in common between the ethanol and water groups in both regions.
