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Chunk #67 — METHODS — FinnGen

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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.
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A GWAS for depression was conducted in FinnGen22 release 6 samples containing 28098 cases (ICD-10/9: F32 or F33) and 228817 controls without manic episodes (ICD10 F30), bipolar affective disorder (ICD-10: F31, ICD-9: 296[2-7], ICD8: 296), persistent mood disorders (ICD10: F34) or other or unspecified mood disorder (ICD10: F38, F39, ICD-8: 29699). Mood (affective) disorders (ICD-10 F30-F39) from FinnGen release 2 was included in the latest depression GWAS meta-analysis by Levey et al. 24, but the current study includes depression cases (ICD-10 F32-F33) from FinnGen release 6 for the first time.