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Chunk #9 — Methods and Materials — Construction of PRSs

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High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk.
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PRS analyses were performed separately in AA subjects using PRSs derived from the MVP AA dataset. The relatively small number of subjects (4%) with non-EA, non-AA ancestries were not included in PRS analyses.