Public domain SNP databases, such as dbSNP (19) and widely used SNP searching tools such as SNPper (27) contain well-organized catalogs of SNPs and provide entry portals to search for fundamental information about SNPs. However, searching for the information necessary to prioritize SNPs requires specialized Web servers, such as PupaSNP Finder (28), Wjst's system (29), PolyMAPr (30) and SNPselector (31). These servers usually integrate information from a variety of databases and analytical tools.
