the Nav1.6 voltage-gated sodium channel to the neuronal membrane which could impact action potential firing rates (O’Brien et al. 2012). As the Map1b gene and protein was significantly upregulated and contained 16 differentially expressed phosphopeptides in the DS of HAP relative to LAP mice, these alterations in Map1b across lines could contribute to the enhanced excitability in HAP MSNs reported in our prior study (Fritz et al. 2019).